Abnormal Blood and Semen Test Results Before Pregnancy - Obstetrics and Gynecology

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Health checkup


Hello doctor, my husband and I underwent pre-pregnancy check-ups after our marriage.
My report shows abnormal white blood cells: 5-10, negative for rubella, and negative for varicella antibodies.
My husband's report indicates abnormal white blood cells in his semen.
What do these results mean? How can we improve this situation? Do we need to seek medical attention immediately? Thank you!

Awei, 30~39 year old female. Ask Date: 2015/04/29

Dr. Cao Guotao reply Obstetrics and Gynecology


Hello, pre-pregnancy check-up after marriage: German measles (rubella): negative, chickenpox antibodies: negative, vaccination is recommended.
Your husband should see a urologist for examination.
Wishing you good health.

Reply Date: 2015/04/29

More Info


Understanding abnormal blood and semen test results before pregnancy is crucial for ensuring a healthy conception and pregnancy. Based on your report, there are a few key points to address regarding your blood test results and your husband's semen analysis.

1. Abnormal White Blood Cell Count: A white blood cell (WBC) count that is outside the normal range can indicate various conditions. In the context of pregnancy planning, it is essential to understand whether the elevated WBC count is due to an infection, inflammation, or another underlying health issue. Elevated WBC counts can sometimes suggest that the body is fighting an infection, which could potentially affect fertility or the health of a future pregnancy. It is advisable to consult with your healthcare provider to determine the cause of the abnormal count and whether any treatment is necessary.

2. Negative Rubella and Varicella Antibodies: The negative results for rubella (German measles) and varicella (chickenpox) antibodies indicate that you are not immune to these infections. This is significant because contracting rubella or varicella during pregnancy can lead to serious complications for the fetus, including congenital defects. It is recommended that you receive vaccinations for these diseases before attempting to conceive. The rubella vaccine is particularly important, as rubella infection during the first trimester can cause severe fetal anomalies.

3. Husband's Semen Analysis: The report indicating abnormal white blood cells in your husband's semen could suggest an infection or inflammation in the reproductive tract, which can affect sperm quality and fertility. High levels of white blood cells in semen (a condition known as leukocytospermia) can be associated with reduced fertility. It is crucial for your husband to consult a urologist or a fertility specialist to evaluate the cause of the abnormality and to discuss potential treatments. Improving lifestyle factors such as diet, exercise, and avoiding smoking or excessive alcohol can also help improve semen quality.

4. Next Steps: Given the findings from both your blood tests and your husband's semen analysis, it is advisable to schedule a follow-up appointment with your healthcare provider. They can provide a comprehensive evaluation and recommend any necessary treatments or lifestyle changes. If there are underlying infections or health issues, addressing them before conception can significantly improve your chances of a healthy pregnancy.

5. General Recommendations: In preparation for pregnancy, both partners should focus on maintaining a healthy lifestyle. This includes a balanced diet rich in fruits, vegetables, whole grains, and lean proteins, regular exercise, adequate sleep, and stress management. Additionally, both partners should avoid harmful substances, including tobacco and excessive alcohol, as these can negatively impact fertility and pregnancy outcomes.

In summary, while the results of your tests may raise some concerns, they also provide an opportunity for proactive health management. By addressing these issues with your healthcare provider, you can take important steps toward ensuring a healthy pregnancy in the future.

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