Does Generalized Anxiety Disorder Increase Cancer Risk? - Psychiatry

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Anxiety disorder issues?


I would like to ask the doctor: Recently, I saw reports stating that according to statistics, patients with generalized anxiety disorder have more than double the risk of developing cancer compared to the general population.
Is this true? As a patient, I feel a bit upset hearing this.
Thank you.

Steve, 40~49 year old female. Ask Date: 2015/05/01

Dr. Huang Weiqin reply Psychiatry


Dear Inquirer: Hello, regarding the relationship between anxiety disorder patients taking medication and the risk of developing cancer, the results are still inconclusive.
Please do not worry excessively.
It is recommended that you engage in regular exercise and health management, as this will significantly reduce the incidence of physical and mental illnesses, including cancer.
Thank you for your question.

Reply Date: 2015/05/01

More Info


Generalized Anxiety Disorder (GAD) is a common mental health condition characterized by excessive worry and anxiety about various aspects of life. The question of whether individuals with GAD have a higher risk of developing cancer is a complex one, and the current body of research provides mixed results.

Recent studies have suggested a potential link between chronic anxiety and an increased risk of various health issues, including cancer. However, it is essential to understand that correlation does not imply causation. While some studies indicate that individuals with anxiety disorders may have a higher incidence of certain types of cancer, the reasons for this association are not entirely clear. Factors such as lifestyle choices, stress levels, and the overall impact of anxiety on the immune system may play significant roles.

One of the primary concerns is that chronic anxiety can lead to prolonged stress, which has been shown to affect the immune system negatively. A weakened immune system may reduce the body's ability to fight off diseases, including cancer. However, it is crucial to note that having anxiety does not mean that one will inevitably develop cancer. Many individuals with anxiety disorders live healthy lives without ever developing cancer.

Moreover, the medications commonly prescribed for anxiety, such as selective serotonin reuptake inhibitors (SSRIs), have not been conclusively linked to an increased risk of cancer. For instance, Cymbalta (duloxetine), a medication often prescribed for anxiety, has not shown evidence of increasing cancer risk in humans, despite some animal studies suggesting otherwise. It is vital to discuss any concerns about medication side effects with a healthcare provider, as they can provide personalized advice based on individual health profiles.

Additionally, lifestyle factors associated with anxiety, such as poor diet, lack of exercise, and substance use (like smoking or excessive alcohol consumption), may contribute to an increased cancer risk. Therefore, managing anxiety through healthy lifestyle choices, therapy, and medication can be beneficial not only for mental health but also for overall physical health.

In summary, while there may be some evidence suggesting a potential link between generalized anxiety disorder and an increased risk of cancer, it is not a definitive conclusion. It is essential for individuals with GAD to focus on managing their anxiety through appropriate treatment and lifestyle changes. Regular check-ups and open communication with healthcare providers can help address any concerns and ensure that both mental and physical health are prioritized. If you are feeling anxious about your health, it is always a good idea to discuss these feelings with a mental health professional who can provide support and guidance tailored to your situation.

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