Vitreous Fibrosis: Is It Malignant and What to Do? - Ophthalmology

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Hello, Dr. Gao?


Good morning, Doctor.
I just received your response.
Is the vitreous fiber a malignant lesion? It seems to be getting larger, which is quite strange.
Is there any need for further examination? When you mentioned that it will gradually alleviate, does that mean it will shrink? Thank you.

Fei, 20~29 year old female. Ask Date: 2015/05/18

Dr. Gao Pilin reply Ophthalmology


Hello, Fei: Vitreous syneresis is not a malignant condition, and its shape can change.
This phenomenon occurs when the vitreous humor liquefies, which is normal.
Sometimes it may persist, change shape, or even disappear; however, once you get used to it, you usually can ignore it.
However, if there are changes in your visual field or a decline in vision, it may indicate retinal pathology, and you should seek an examination.
Thank you for your message.

Reply Date: 2015/05/18

More Info


Vitreous fibrosis, often referred to in the context of ocular health, is a condition characterized by the abnormal proliferation of fibrous tissue within the vitreous body of the eye. This condition can arise due to various factors, including aging, inflammation, or trauma. It is essential to clarify that vitreous fibrosis itself is not inherently malignant. However, it can be associated with other ocular conditions that may have malignant potential, such as retinal detachment or proliferative vitreoretinopathy.

When discussing whether vitreous fibrosis is malignant, it is crucial to differentiate between the fibrotic changes in the vitreous and the presence of any underlying malignancy. Vitreous fibrosis typically does not indicate cancer; rather, it is a response to injury or inflammation. However, if there are accompanying symptoms such as vision changes, floaters, or flashes of light, it may warrant further investigation to rule out any serious conditions.

In terms of management, the approach to vitreous fibrosis largely depends on the symptoms and the extent of the fibrosis. If the condition is asymptomatic and not affecting vision, it may simply be monitored over time. Regular eye examinations are essential to track any changes in the vitreous and overall eye health. If the fibrosis progresses or begins to impact vision, more invasive interventions, such as vitrectomy (surgical removal of the vitreous gel), may be considered.

Regarding your concern about the fibrosis "getting longer," it is important to consult with an ophthalmologist who can perform a thorough examination, including imaging studies like optical coherence tomography (OCT) or ultrasound, to assess the extent of the fibrosis and its impact on the retina and surrounding structures. These tests can provide valuable information about the nature of the fibrosis and whether any treatment is necessary.

The term "slowly resolving" typically refers to the natural course of some fibrotic conditions, where the body may gradually reabsorb the fibrous tissue over time. However, this is not guaranteed, and the behavior of vitreous fibrosis can vary significantly from person to person. Some individuals may experience stabilization or even improvement, while others may see progression.

In summary, vitreous fibrosis is generally not a malignant condition, but it requires careful monitoring and evaluation by an eye care professional. If you notice any changes in your vision or have concerns about the progression of the fibrosis, it is crucial to seek medical advice promptly. Regular follow-ups and appropriate imaging can help ensure that any potential complications are addressed early, maintaining optimal eye health.

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