Painful Testicular Lumps: Epididymitis vs. Cancer - Urology

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Small hard lump on the upper left side of the testicle?


Hello, Dr.
Hsu! I have discovered a small, rice-sized hard lump located just above the left testicle, presumably at the head of the epididymis, which is extremely painful to touch.
Could this possibly be epididymitis? I did some research online, and it seems that testicular cancer usually presents as a painless lump.
It doesn't seem likely to be testicular cancer.
Based on your experience, which possibility is more likely?

OTTO, 30~39 year old female. Ask Date: 2015/06/04

Dr. Xu Weikai reply Urology


OTTO: Hello, if you can be 100% certain that the lesion is in the epididymis, then the chances of it being malignant are very low.
Testicular cancer typically does not cause pain; however, if it compresses nearby nerves or blood vessels, it can lead to discomfort.
Additionally, if there is persistent pain, it may be due to an infection, and you should seek medical attention promptly.
Otherwise, if the condition worsens, it could lead to a blockage of the vas deferens, resulting in infertility.
If there are any unclear points, feel free to ask again, and we can discuss and research further.
Answers found online should only be used as a reference; it is essential to seek care at a medical facility when necessary.
The Ministry of Health and Welfare Taitung Hospital cares about you.

Reply Date: 2015/06/04

More Info


Dear Patient,
Thank you for your inquiry regarding the painful lump you have discovered in the area above your left testicle, which you suspect may be related to the epididymis. Your concern is valid, and it is essential to differentiate between potential causes of testicular lumps, particularly epididymitis and testicular cancer.

Epididymitis is an inflammation of the epididymis, the coiled tube located at the back of the testicle that stores and matures sperm. This condition is often associated with pain and swelling, and it can be caused by infections, sexually transmitted infections, or even non-infectious factors such as trauma. The fact that you are experiencing extreme tenderness upon touching the lump suggests that inflammation is likely, as testicular cancer typically presents as a painless mass.

On the other hand, testicular cancer often manifests as a hard, painless lump on the testicle itself. While it is true that some forms of testicular cancer can present with pain, especially if there is associated bleeding or if the tumor is large enough to cause discomfort, the classic presentation is indeed a painless mass. The size of the lump you described as being "like a grain of rice" is relatively small, and while testicular cancer can occur at any size, the characteristics you mentioned lean more towards an inflammatory process rather than malignancy.

In clinical practice, the likelihood of epididymitis is generally higher in cases where there is significant pain and tenderness, especially if there are accompanying symptoms such as fever, swelling, or discharge. It is also important to consider your medical history, sexual activity, and any recent infections, as these factors can contribute to the development of epididymitis.

To further evaluate your condition, I recommend the following steps:
1. Consult a Healthcare Provider: It is crucial to see a urologist or your primary care physician for a thorough examination. They will perform a physical examination and may order an ultrasound of the scrotum to assess the lump's characteristics and determine if there is any fluid accumulation or other abnormalities.

2. Consider Laboratory Tests: Depending on the findings, your doctor may recommend urine tests or blood tests to check for signs of infection or other underlying issues.

3. Follow-Up: If the lump is determined to be inflammatory, appropriate treatment may include antibiotics if an infection is present, or anti-inflammatory medications to reduce pain and swelling. If there is any suspicion of malignancy, further imaging or a biopsy may be necessary.

In conclusion, while both epididymitis and testicular cancer are potential causes of a lump in the testicular area, the presence of significant pain and tenderness strongly suggests that epididymitis is more likely. However, only a medical professional can provide a definitive diagnosis through examination and appropriate testing. Please do not delay in seeking medical attention, as timely evaluation is essential for the best outcomes.

Wishing you good health and a swift resolution to your concerns.

Best regards.

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