Nail Fungus and Athlete's Foot: Treatment and Side Effects - Dermatology

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Onychomycosis, athlete's foot?


Hello Dr.
Lee,
I started taking Fungitech on May 7 and continued for four weeks, stopping on June 4 due to my follow-up appointment being over a month away, which prevented me from obtaining a refill.
Three days after stopping the medication (on June 7), I began to develop itchy rashes all over my body that became increasingly severe and widespread with scratching, leading me to use ice packs for relief.

Could this be related to the medication, or could it be due to other factors? What should I do next? I have been struggling with athlete's foot and onychomycosis for a long time, and after switching to oral medication, I noticed significant improvement.
Now that I cannot continue the treatment, I am quite confused and would appreciate your guidance.
Thank you!

Niming, 60~69 year old female. Ask Date: 2015/06/09

Dr. Li Yufen reply Dermatology


Hello: The guidelines for the use of Fungitech tablets in the treatment of onychomycosis (fungal nail infection) under Taiwan's National Health Insurance are as follows: It is indicated for cases of tinea unguium affecting fingernails and toenails.
The recommended dosage is 250 mg daily.
For fingernail infections, the maximum supply is limited to 42 tablets, which must be completed within 8 weeks.
For toenail infections, the maximum supply is limited to 84 tablets, which must be completed within 16 weeks.
After the completion of treatment, re-administration of this medication or any other similar oral antifungal agents is not permitted within 6 and 12 months, respectively.
It is advised that if you are considering oral treatment for onychomycosis, you must attend follow-up appointments regularly.
Regarding the appearance of new rashes on your body, it is recommended that you consult a dermatologist to confirm whether it is a typical drug rash or another skin condition.
Thank you!

Reply Date: 2015/06/09

More Info


Hello! Thank you for your detailed inquiry regarding your ongoing issues with nail fungus (onychomycosis) and athlete's foot (tinea pedis), as well as the side effects you've experienced after discontinuing your medication.
From your description, it seems that you have been dealing with persistent fungal infections, which can be quite challenging to manage. The medication you mentioned, Fungitech (likely containing terbinafine or a similar antifungal), is typically effective for treating both athlete's foot and nail fungus. However, it’s important to understand that these conditions can take time to resolve completely, and the treatment duration often extends beyond just a few weeks.

The rash and intense itching you experienced after stopping the medication could be related to several factors. It’s possible that your body is reacting to the sudden withdrawal of the antifungal treatment, especially if the medication was effectively controlling the fungal infection. When antifungal treatment is halted, the underlying fungal infection may resurface, leading to symptoms such as itching and rashes. Additionally, if you have been using topical antifungals intermittently, there might be a possibility of developing a sensitivity or allergic reaction to one of the ingredients in those products.

Another consideration is that the rash could be a manifestation of a secondary infection or a different dermatological condition altogether, such as eczema or contact dermatitis, which can be exacerbated by moisture and sweat, especially in the summer months. Given your history of excessive sweating, this could also contribute to skin irritation and the development of rashes.

Here are some recommendations for managing your situation:
1. Consult a Dermatologist: Since you have experienced a significant reaction after stopping your medication, it would be wise to consult a dermatologist. They can evaluate the rash, determine if it’s related to the previous treatment, and possibly prescribe a different antifungal or topical steroid to alleviate the itching and inflammation.

2. Maintain Hygiene: Continue to keep your feet clean and dry. Change socks regularly, especially if they become damp from sweat. Consider using moisture-wicking socks and breathable footwear to reduce sweating and moisture buildup.

3. Topical Treatments: While you await your appointment, you might consider using over-the-counter antifungal creams (like clotrimazole or miconazole) to manage any resurfacing fungal infection. However, be cautious and monitor for any adverse reactions.

4. Avoid Scratching: It’s crucial to avoid scratching the affected areas, as this can lead to further irritation or secondary bacterial infections. Ice packs can help alleviate itching temporarily.

5. Follow-Up on Medication: If your dermatologist prescribes a new antifungal treatment, ensure you follow the full course of treatment as directed. Sometimes, a longer duration is necessary for complete resolution, especially for nail fungus.

6. Lifestyle Adjustments: Consider lifestyle changes that can help manage your symptoms, such as using antifungal powders in your shoes, avoiding tight-fitting footwear, and ensuring your shoes are well-ventilated.

7. Monitor for Allergies: If you suspect that the rash may be an allergic reaction, keep a diary of your symptoms and any new products you’ve used, including soaps, detergents, or topical treatments.

In summary, while your initial treatment seemed effective, the subsequent rash and itching could be due to a variety of factors, including the re-emergence of the fungal infection or a new dermatological issue. Consulting with a dermatologist will provide you with the best course of action tailored to your specific situation. Remember, managing fungal infections can be a lengthy process, and patience is key. Thank you for reaching out, and I hope you find relief soon!

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