Macular Degeneration: Symptoms and Diagnosis Challenges - Ophthalmology

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Macular degeneration


When not wearing glasses, I notice that when I focus on the center of a tile, I see a blob, and then the tile's pattern appears to bend and distort.
Additionally, when I stare into a dark area, I can initially see something, but after a while, it completely goes black, almost like I'm blind.
Blinking makes it return to normal.
I have had a fundus examination and imaging done, but no cause has been found.

Niming, 20~29 year old female. Ask Date: 2015/06/09

Dr. Gao Pilin reply Ophthalmology


Hello: When not wearing glasses, objects appear distorted; does this happen when wearing glasses? If it is macular degeneration, distortion should still occur even with glasses.
Staring in the dark for a long time can cause a blackening effect, which I wonder if it is due to an afterimage.
Afterimages and the original image are complementary, and when fused, it seems like there is no image.
However, this is just my speculation, and I am not sure if it is correct; it is for reference only.
If further examination is needed, it is best to visit the retina department at a medical center for a more detailed check-up, as some lesions may not be visible to the naked eye or through photography.
Thank you for your message.

Reply Date: 2015/06/09

More Info


Macular degeneration, particularly age-related macular degeneration (AMD), is a progressive eye disease that affects the macula, the part of the retina responsible for central vision. It can lead to significant visual impairment, especially in tasks that require sharp vision, such as reading or recognizing faces. Your symptoms of seeing distortions in the tile patterns and experiencing temporary blackouts in your vision are concerning and warrant further investigation.

The symptoms you describe, such as seeing a "blob" in the center of your vision and noticing distortions in straight lines, are classic signs of macular degeneration. This condition can manifest in two forms: dry and wet AMD. Dry AMD is more common and progresses slowly, while wet AMD can lead to rapid vision loss due to abnormal blood vessel growth beneath the retina. The temporary blackouts you experience could be related to fluctuations in retinal function or even transient ischemic attacks, which are temporary reductions in blood flow to the brain.

Diagnosing macular degeneration can be challenging, especially in its early stages. Standard examinations, such as fundus photography and optical coherence tomography (OCT), are essential tools for assessing the health of the retina and identifying any abnormalities. However, in some cases, these tests may not reveal the underlying issues, particularly if the changes are subtle or if the disease is in its early stages.
Given your experience of having your vision temporarily go black and then return upon blinking, it might be beneficial to consider a few additional diagnostic approaches. These could include:
1. Amsler Grid Test: This simple self-test can help you monitor changes in your central vision. It involves looking at a grid of lines and noting any distortions or areas of missing vision. Regularly performing this test can help you track any progression of symptoms.

2. Fluorescein Angiography: This test involves injecting a dye into your bloodstream and taking photographs of the retina as the dye passes through the blood vessels. It can help identify any leakage or abnormal blood vessel growth associated with wet AMD.

3. Visual Field Testing: This can assess your peripheral vision and help identify any blind spots or areas of reduced vision that may not be apparent during standard eye exams.

4. Consultation with a Retina Specialist: If you haven't already, seeing a specialist who focuses on retinal diseases can provide more targeted insights and treatment options.

In terms of management, while there is currently no cure for macular degeneration, there are treatments available that can slow its progression, particularly for wet AMD. These include anti-VEGF injections, which can help reduce abnormal blood vessel growth. For dry AMD, lifestyle modifications such as a healthy diet rich in antioxidants, regular exercise, and avoiding smoking can be beneficial.

It's crucial to maintain regular follow-ups with your eye care provider, especially given your symptoms. If you notice any changes in your vision, such as increased distortion or new blind spots, seek immediate medical attention. Early detection and intervention can significantly impact the quality of life and visual outcomes for individuals with macular degeneration.
In summary, while your current examinations may not have provided clear answers, the symptoms you're experiencing are significant and should be closely monitored. Consider additional testing and consultations to ensure a comprehensive evaluation of your eye health.

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