the Differences in Morning and Evening Skin Medication Use - Dermatology

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The difference between using topical medications in the morning and at night?


Hello, I would like to ask why some ointments have different instructions for morning and evening use.
I can understand why some should only be used at night.
However, sometimes doctors only ask me to apply them in the morning; what is the reason for this? Isn't it more suitable to apply medication at night while resting? Can the medication also be applied at night? The medication name is Futusoa cream.
Thank you.

Jenny, 20~29 year old female. Ask Date: 2015/06/23

Dr. Li Yufen reply Dermatology


Hello: Some photosensitive ointments specifically indicate that they should be applied at night.
However, for Futusoa cream, it can be applied either in the morning or at night.
Thank you!

Reply Date: 2015/06/23

More Info


The timing of applying topical medications, such as creams and ointments, can significantly influence their effectiveness and the overall treatment outcome. The differences in morning and evening applications often stem from the pharmacological properties of the medication, the nature of the skin condition being treated, and the environmental factors that may affect the skin throughout the day.

Firstly, some topical medications are designed to work best during specific times of the day due to their active ingredients. For instance, certain medications may be photosensitive, meaning they can react adversely to sunlight. These medications are typically recommended for evening use to minimize exposure to UV rays, which could lead to skin irritation or reduced efficacy. In contrast, other medications may contain ingredients that are better absorbed or more effective when applied during the day, especially if they are intended to protect the skin from environmental factors like pollution or dryness.

In the case of Futuosa cream, which is often used for various dermatological conditions, it is important to note that it can be applied both in the morning and at night. This flexibility allows patients to incorporate it into their daily routine based on their specific needs and the advice of their healthcare provider. The choice of when to apply the cream may depend on the severity of the skin condition, the patient's lifestyle, and how the skin responds to the treatment.

Moreover, the skin undergoes different physiological changes throughout the day. During the day, the skin is exposed to environmental stressors such as UV radiation, pollution, and temperature fluctuations, which can exacerbate certain skin conditions. Applying a protective or therapeutic cream in the morning can help shield the skin from these stressors. Conversely, nighttime is often considered a restorative period for the skin, making it an ideal time for treatments that promote healing and repair.

Another factor to consider is the interaction between topical medications and other products, such as moisturizers. For example, if a patient is using a topical steroid like Mometasone Furoate, it is generally recommended to apply a moisturizer shortly after bathing to lock in moisture. However, if the steroid and the moisturizer are applied simultaneously, there may be concerns about the efficacy of the steroid being compromised. Therefore, the timing of application can also be crucial in ensuring that each product works effectively.

In summary, the differences in morning and evening application of topical medications are influenced by the pharmacological properties of the drugs, the nature of the skin condition, and the environmental factors affecting the skin. While some medications are best applied at night to avoid sunlight or enhance absorption, others may be more effective during the day to provide protection against environmental stressors. In the case of Futuosa cream, it can be used at any time, allowing for flexibility based on individual needs. Always consult with a healthcare provider for personalized advice on the best application schedule for your specific skin condition.

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