Chronic Urticaria: Exploring Long-Term Treatment Options and Steroid Use - Dermatology

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Chronic urticaria


I have been dealing with chronic urticaria for over four years, but since I visited the doctor a year ago, I have been self-medicating with antihistamines from the pharmacy, and I still haven't improved.
Is there anyone else who has experienced such a long duration without recovery? In the past, during middle school, I had a similar issue that lasted over a year, but I was treated with steroids and gradually tapered off the dosage until I got better.
I would like to know if switching to steroid treatment would be effective for me?

Ke Ke, 20~29 year old female. Ask Date: 2015/07/02

Dr. Li Yufen reply Dermatology


Hello: Chronic urticaria is defined as symptoms lasting for more than 6 weeks, and it can sometimes be difficult to treat.
For more information about urticaria, you can refer to the introduction by the Taiwan Dermatological Association at http://www.derma.org.tw/index.php?sort_no=1402039983 and the presentation by Dr.
Tseng Te-Peng from Shuang Ho Hospital at http://www.slideshare.net/arthritisfound/presentation-for-the-society.
Thank you!

Reply Date: 2015/07/02

More Info


Chronic urticaria, commonly known as chronic hives, can be a challenging condition to manage, especially when it persists for an extended period, as you have experienced over the past four years. The fact that you have been self-medicating with antihistamines without significant improvement raises important considerations regarding the management of your condition and the potential role of corticosteroids.

First, it's essential to understand that chronic urticaria can be classified into two main types: chronic spontaneous urticaria (CSU) and chronic inducible urticaria (CIndU). CSU occurs without any identifiable trigger, while CIndU is triggered by specific stimuli such as pressure, temperature changes, or exercise. Identifying the type of urticaria you have is crucial for effective treatment.

Antihistamines are the first-line treatment for chronic urticaria. They work by blocking the action of histamine, a substance in the body that causes allergic symptoms. However, in some cases, higher doses or a combination of different antihistamines may be necessary to achieve adequate control of symptoms. If you have been using over-the-counter antihistamines without consulting a healthcare professional, it may be beneficial to revisit a doctor who specializes in allergies or dermatology. They can help assess your condition and determine if your current treatment regimen is appropriate.

Regarding the use of corticosteroids, they are indeed effective in reducing inflammation and controlling symptoms in cases of chronic urticaria. However, long-term use of corticosteroids is generally not recommended due to the potential for significant side effects, including weight gain, osteoporosis, hypertension, diabetes, and increased susceptibility to infections. If corticosteroids are considered, they should typically be used for a short duration and under close medical supervision, with a gradual tapering of the dose to minimize withdrawal symptoms and rebound effects.

In your case, if you are contemplating switching to corticosteroid treatment, it is crucial to do so under the guidance of a healthcare provider. They can evaluate your specific situation, including the severity of your symptoms, any underlying conditions, and your overall health status. Additionally, they may suggest alternative treatments such as leukotriene receptor antagonists, omalizumab (a monoclonal antibody), or other immunomodulatory therapies that may be effective for chronic urticaria without the risks associated with long-term corticosteroid use.

Moreover, lifestyle modifications can also play a role in managing chronic urticaria. Keeping a symptom diary to track potential triggers, maintaining a healthy diet, managing stress, and avoiding known allergens can contribute to better control of your symptoms.

In summary, while corticosteroids can be effective for treating chronic urticaria, their long-term use carries risks that must be carefully weighed against the benefits. It is essential to work closely with a healthcare professional to explore all available treatment options, including adjusting your antihistamine regimen and considering alternative therapies. Your experience is not uncommon, and many individuals with chronic urticaria face similar challenges. Seeking specialized care can provide you with the best chance of achieving symptom relief and improving your quality of life.

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