Ventricular Fibrillation and Mitral Valve Prolapse Risks - Cardiology

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Arrhythmia-related issues?


Hello, Doctor: I would like to ask if mitral valve prolapse can lead to the occurrence of ventricular fibrillation.
If so, what is the likelihood? Additionally, what is idiopathic ventricular fibrillation? Where can I find related information? It seems that there is very little information on this topic.
I apologize for the lengthy inquiry.
Thank you.
In 2008, Dr.
A at a hospital in northern Taiwan mentioned that I might have mitral valve prolapse.
Since I had no obvious symptoms and no significant issues, treatment was not necessary, but I was prescribed antiarrhythmic medication.
However, after taking the medication, my heart rate dropped below 40 beats per minute, and my blood pressure fell to around 60/40, so I stopped taking it after two doses.

In 2013, I was diagnosed with narcolepsy at a hospital in central Taiwan and began taking modafinil and methylphenidate.
A year later (2014), Dr.
B suggested I consult Dr.
C, the head of cardiology at the same hospital, to confirm whether I had any heart problems, which would help in adjusting my medication dosage.
After seeing the cardiologist, my heart was found to be normal, but I underwent a tilt table test, which resulted in cardioinhibitory response, with EKG recording showing asystole.
I received CPR for 10 seconds and then regained spontaneous circulation.
During a follow-up, Dr.
C informed me that my condition is very rare both domestically and internationally, and he was unsure of the cause, so he would look into the literature and call me for a follow-up.
After six months, I underwent a comprehensive health check-up at my own expense.
During a painless colonoscopy and gastroscopy under general anesthesia, there were cardiac issues, and I woke up two and a half hours later feeling weak.
The nurse advised me to be particularly cautious before and after anesthesia.
When I reviewed the report and asked Dr.
D at the health check-up center about this, I was referred back to Dr.
C for consultation.
I was later informed that it was a vagal reflex - cardioinhibitory type, and the cardiology team decided that I needed a pacemaker, as it was difficult to manage with medication.
They mentioned hospitalization and arranged for Dr.
E to perform a cardiac catheterization.
After being hospitalized, Dr.
E informed me that all my EKGs and echocardiograms were normal, and there was no need for a pacemaker.
However, during the cardiac catheterization the next day, I suddenly experienced ventricular fibrillation.
I received CPR followed by defibrillation, and after about a minute of CPR, I regained consciousness but was unable to speak, with weakness on my left side and spasms on my right side.
After consulting with a neurologist, it was suspected that I might have had a stroke, and I underwent a CT scan and was sent to the intensive care unit.
A few hours later, another Dr.
F was urgently contacted to perform an implantable cardioverter-defibrillator surgery.
Throughout the day, Dr.
E and Dr.
F frequently checked on my condition in the ICU but only mentioned that I had a lethal arrhythmia that was malignant and easily triggered, possibly due to genetic mutations or congenital issues.
The cardiologists also discussed whether my narcolepsy could be a symptom generated by the heart, as I had averaged over 12 hours of sleep daily since childhood and would suddenly fall asleep during the day, although it was suspected that this might be a form of brief unconsciousness.
I was hospitalized for six days, and everything happened so quickly.
It has been a month since my discharge, and I have started cardiac rehabilitation.
However, I am still very confused as to why I am the only one in my family with heart problems, especially since the episodes occurred without any symptoms or warning signs, and I felt no discomfort.
Additionally, the defibrillation was extremely painful, and I had significant burns on my chest.
The entire process was intense, and I was startled awake at home after discharge due to the memory of the shock.
Given my lack of understanding of this condition, I fear that I might not wake up the next moment, which makes me reluctant to sleep for long periods.
I also have a fear of the defibrillation experience.
Since my attending physician is abroad and the psychologist will not return until the end of August, I am currently unable to discuss this.
At this stage, I need to seek help to understand and alleviate my fears.

H, 20~29 year old female. Ask Date: 2015/07/08

Dr. He Dongjin reply Cardiology


Hello, this matter should not be related to the mitral valve prolapse.
As for your question, to be honest, I do not know.
I do not have the relevant medical records on hand, and the doctors present are unable to provide an explanation.
We cannot make assumptions without reviewing the medical history.
I apologize for this.
It would be best to discuss it in detail with the physician during your next appointment.
Changhua Hospital cares about you.

Reply Date: 2015/07/08

More Info


Ventricular fibrillation (VF) and mitral valve prolapse (MVP) are two significant cardiac conditions that can have serious implications for heart health. Understanding the relationship between these conditions and the risks associated with them is crucial for patients, especially those with a history of cardiac issues.

Mitral Valve Prolapse and Ventricular Fibrillation
Mitral valve prolapse is a condition where the mitral valve does not close properly, which can lead to mitral regurgitation (MR). While MVP is often benign and may not cause significant symptoms or complications, it can be associated with arrhythmias, including ventricular fibrillation. However, the direct causative link between MVP and VF is not well established. The risk of developing VF in patients with MVP is generally considered low, especially if there are no other underlying heart conditions or significant MR.
In patients with MVP, the risk of arrhythmias can increase if there are additional factors such as structural heart disease, a history of syncope, or other arrhythmogenic conditions. Therefore, while MVP can be associated with an increased risk of arrhythmias, the likelihood of VF specifically occurring due to MVP alone is relatively low.

Idiopathic Ventricular Fibrillation
Idiopathic ventricular fibrillation refers to VF that occurs without any identifiable structural heart disease or other clear causes. This condition can be particularly concerning because it can lead to sudden cardiac arrest without warning. The mechanisms behind idiopathic VF are not fully understood, but it is thought to involve genetic factors, autonomic nervous system imbalances, or other triggers that are not yet well defined.

Patients with idiopathic VF often undergo extensive testing to rule out underlying heart conditions, including echocardiograms, Holter monitoring, and sometimes genetic testing. The rarity of this condition can make it challenging for both patients and healthcare providers to manage effectively.

Seeking Information and Support
For patients seeking more information about these conditions, reputable sources include:
1. American Heart Association (AHA): This organization provides comprehensive resources on various heart conditions, including MVP and arrhythmias.

2. National Institutes of Health (NIH): The NIH offers research-based information on cardiovascular diseases and conditions.

3. Peer-reviewed medical journals: Journals such as the Journal of the American College of Cardiology (JACC) and Circulation often publish studies and reviews on the latest findings related to cardiac health.

Managing Anxiety and Fear
It is understandable to feel anxious or fearful after experiencing serious cardiac events like VF. Here are some strategies to help manage these feelings:
1. Education: Understanding your condition can empower you and reduce fear. Ask your healthcare provider for resources or explanations about your specific situation.

2. Support Groups: Connecting with others who have similar experiences can provide emotional support and practical advice.

3. Mental Health Support: Consider speaking with a mental health professional who specializes in chronic illness or anxiety management. They can help you develop coping strategies.

4. Regular Follow-ups: Maintaining regular appointments with your cardiologist can help monitor your condition and provide reassurance.

In conclusion, while mitral valve prolapse can be associated with arrhythmias, the direct link to ventricular fibrillation is not strong unless other risk factors are present. Understanding these conditions, seeking reliable information, and addressing emotional concerns through support and education are essential steps in managing your heart health and overall well-being. Always consult with your healthcare provider for personalized advice and treatment options.

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