Cardiovascular Concerns: Low Fibrinogen and WBC Levels

Cardiovascular Concerns - Fibrinogen + WBC (White Blood Cell Count)

Hello Doctor,
I recently underwent a health check-up and encountered several unusual indicators that I couldn't find comprehensive information about online.
I would appreciate it if you could take the time to respond to my current situation:
- Male
- Height: 176 cm
- Weight: 74 kg
- Over the past three years, I have managed my weight, diet, and exercise, reducing it from 86 kg to 74 kg.
Issues:
- Resting EKG: Counterclockwise axis deviation
- Fibrinogen: Low at 184.1 (Standard: 200-400)
- White Blood Cell Count (WBC): 4.32 (Standard: 4.5)
My cholesterol levels have dropped to within the normal range, and both body fat and visceral fat are also within standard limits.
However, I still have mild fatty liver.
Thank you,
Jackie

Jackie, 40~49 year old female. Ask Date: 2015/07/11

Dr. Li Han reply Cardiology

Hello Jackie, based on your statement, your Body Mass Index (BMI) is approximately 24, which is within the normal range.
Your diet and exercise are normal, and the listed data is only at the lower edge of the normal values, which should be considered normal variants.
As for body fat control, you just need to continue managing it through diet and exercise.
Take care, and the Changhua Hospital of the Ministry of Health and Welfare is concerned about you.

Reply Date: 2015/07/11

More Info

Hello Jackie,
Thank you for reaching out with your concerns regarding your recent health indicators. It’s great to hear that you have been actively managing your weight and lifestyle, which is a significant step towards maintaining good cardiovascular health. Let’s break down the specific issues you mentioned: low fibrinogen levels, low white blood cell (WBC) counts, and the findings from your resting EKG.

Low Fibrinogen Levels
Fibrinogen is a protein produced by the liver that plays a crucial role in blood clotting. Normal levels typically range from 200 to 400 mg/dL. Your reported level of 184.1 mg/dL is indeed below the normal range. Low fibrinogen levels can be indicative of several conditions, including:
1. Liver Disease: Since fibrinogen is produced in the liver, any liver dysfunction can lead to decreased production.

2. Disseminated Intravascular Coagulation (DIC): This is a serious condition that causes abnormal blood clotting throughout the body's blood vessels.

3. Malnutrition: Insufficient protein intake can lead to low fibrinogen levels.

4. Inflammatory Conditions: Certain chronic inflammatory diseases can also affect fibrinogen levels.

Given your history of managing your weight and diet, it would be prudent to evaluate your liver function through additional tests, especially if you have any symptoms like jaundice, abdominal pain, or changes in appetite.

Low White Blood Cell (WBC) Count
A WBC count of 4.32 is slightly below the normal range (typically around 4.5 to 11.0 x 10^9/L). A low WBC count, or leukopenia, can result from various factors, including:
1. Bone Marrow Disorders: Conditions that affect the bone marrow can lead to decreased production of white blood cells.

2. Autoimmune Disorders: Diseases where the immune system attacks the body can also lower WBC counts.

3. Infections: Certain viral infections can temporarily reduce WBC levels.

4. Nutritional Deficiencies: Deficiencies in vitamins such as B12 or folate can impact WBC production.

Since your WBC count is marginally low, it may be beneficial to monitor it over time and consider further testing if you experience any recurrent infections or other symptoms.

Resting EKG Findings
The resting EKG showing counterclockwise axis deviation and early repolarization can indicate several things. Counterclockwise axis deviation might suggest left ventricular hypertrophy or other structural heart changes, while early repolarization is often considered a benign finding, especially in younger individuals or athletes. However, it can sometimes be associated with an increased risk of arrhythmias.

Recommendations
1. Follow-Up Testing: It would be wise to discuss these findings with your healthcare provider. They may recommend additional tests, such as liver function tests, a complete blood count (CBC) with differential, and possibly imaging studies if there are concerns about your heart or liver.

2. Lifestyle Considerations: Continue your healthy lifestyle practices, including a balanced diet rich in proteins, vitamins, and minerals, regular exercise, and adequate hydration. These can help support your overall health and may positively influence your blood parameters.

3. Monitoring: Regular follow-up appointments to monitor your fibrinogen and WBC levels, as well as your cardiovascular health, will be essential. If you notice any new symptoms, such as unusual bruising, fatigue, or signs of infection, seek medical attention promptly.

In summary, while your low fibrinogen and WBC levels warrant further investigation, they can often be managed effectively with appropriate medical guidance and lifestyle adjustments. Please ensure to maintain open communication with your healthcare provider regarding these findings and any symptoms you may experience.

Best wishes for your health journey!

Similar Q&A

Understanding Low Fibrinogen Levels: Do You Need Further Treatment?

Hello Dr. Lin, I would like to ask if a low fibrinogen level of 184.1 (normal range: 200-400) and a white blood cell (WBC) count of 4.32 (normal range: 4.5) would require any additional treatment. Thank you for your assistance.

Dr. Lin Jixiong reply Cardiology
Hello: The provided test values show only slight abnormalities when compared to the normal range. It is difficult to determine the specific issue based solely on the blood test data; clinical symptoms and other examinations must be considered to confirm the most likely conditions...

Understanding Low Blood Pressure and Its Impact on Heart Health

My platelet count is around 80,000. It was first discovered six years ago when I was pregnant with my first child. Before delivery, it dropped to a low of 25,000. During my pregnancy, I regularly consulted a hematologist. About a year ago, I started seeing a hematologist in my cu...

Dr. Zhuang Junbin reply Cardiology
Dear Concerned Individual, 1. The abnormal sounds detected through the stethoscope may indicate arrhythmia or heart murmurs; however, it is also possible that this is not the case. It is advisable to consult a cardiologist for further evaluation. 2. The sudden sharp pain in you...

Understanding Low White Blood Cell Count and Abnormalities in Cancer Care

I am concerned about not wanting to frequently visit the hospital and occupy medical resources, but I also worry that if there is a real issue, it may delay treatment. Therefore, I would like to ask Dr. Chen whether my situation requires further examination. Examination data: I...

Dr. Chen Yunfang reply Oncology
Hello: 1. The white blood cell count is unremarkable. You can decide whether to seek medical attention; if so, you should consult a hematologist. 2. Similarly, if you choose to seek medical attention, you can also see a hematologist. 3. These abnormalities do not have any particu...

Elevated White Blood Cell Count and Heart Rate: Understanding Your Symptoms

Hello Dr. Lin, I am a 30-year-old female, currently maintaining a normal daily routine, going to bed before 11 PM and waking up at 8 AM. I am a homemaker and have activities scheduled every day. I have transitioned from the Department of New Medicine to the Department of Nephrol...

Dr. Lin Jixiong reply Cardiology
Hello: Based on your white blood cell data, there has been a consistent increase from March 31 to April 20, indicating that your body may be experiencing an infection. Additionally, the clinical symptoms of bone pain and fatigue are also similar to those associated with an infect...