Pathology Reports: Insights on Genital Warts in Pregnant Women - Urology

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Pathology Report


Hello, doctor.
I would like to ask about a skin tag that has developed in the groin area of a pregnant woman (located about 3 cm to the right of the thigh, between the genitalia and the anus).
The skin tag is approximately 0.8 cm in height and has thin, thread-like skin above it, appearing dark in color (similar to the surrounding skin tone).
During a McDonald procedure, the surgeon removed it using electrosurgery and sent it for pathological examination.
Since there were no other lesions, only this one was treated with electrosurgery.
A few days later, the pathology report indicated the presence of a viral wart.
The doctor mentioned that the pathologist noted the biopsy did not exhibit the typical appearance of condyloma, so it cannot be definitively identified as such.
However, due to the unusual location, the doctor advised wearing protective clothing.
I would like to ask if any further tests are necessary.
Does the unclear result indicate that it may develop into condyloma?

Mr. Fu, 20~29 year old female. Ask Date: 2015/07/14

Dr. Xu Weikai reply Urology


Mr.
Fu: Hello, you can observe the local area to see if there are any signs of recurrence.
If there are, a biopsy can be performed again.
Additionally, blood tests and DNA analysis for HPV can confirm if there is a HPV infection.
As for whether clothing isolation is necessary, I recommend that you wash your clothes separately or disinfect them with bleach.
After three months, if no new lesions appear, it can be considered healed.
If you have any further questions, feel free to ask, and we can discuss and research together.
Online responses should only be used as a reference; it is essential to seek medical care at a healthcare facility if needed.
The Ministry of Health and Welfare Taitung Hospital cares about you.

Reply Date: 2015/07/14

More Info


When it comes to genital warts, particularly in pregnant women, understanding the pathology reports and the implications of such findings is crucial for both maternal and fetal health. Genital warts, caused by certain strains of the human papillomavirus (HPV), can present unique challenges during pregnancy.
In your case, the pathology report indicated the presence of "viral warts," but it did not confirm a diagnosis of condylomata acuminata (the medical term for genital warts). The absence of typical cauliflower-like appearances in the histological examination means that while the lesion is associated with HPV, it may not fit the classic presentation of genital warts. This uncertainty can be concerning, especially when considering the implications for treatment and management during pregnancy.

Understanding the Pathology Report:
1. Viral Warts: The report confirms the presence of viral warts, which suggests an HPV infection. However, the lack of definitive characteristics for condylomata acuminata means that further monitoring may be necessary.

2. Histological Examination: The histological findings are critical. If the lesion does not exhibit the typical features of genital warts, it may warrant further investigation. This could include additional biopsies or monitoring over time to assess any changes in the lesion.

Implications for Pregnancy:
- Transmission Risks: While HPV is common, the risk of transmission to the fetus during delivery is low, particularly if the warts are not extensive. However, if warts are present in the birth canal, there is a potential risk of respiratory papillomatosis in the newborn, a rare condition where warts develop in the respiratory tract.

- Management Options: Treatment options for genital warts during pregnancy are limited due to potential risks to the fetus. Topical treatments like imiquimod and podophyllin are generally avoided. Instead, procedures like cryotherapy or electrosurgery may be performed, as was done in your case. However, these should be approached with caution and typically only if the warts are causing significant discomfort or complications.

Recommendations Moving Forward:
1. Follow-Up: Regular follow-up appointments with your obstetrician or a specialist in maternal-fetal medicine are essential. They can monitor the lesion and any potential changes during the pregnancy.

2. Consultation with a Dermatologist: Given the unique characteristics of the lesion, consulting with a dermatologist who specializes in skin conditions during pregnancy may provide additional insights and management options.

3. Avoiding Irritation: As advised by your physician, wearing loose-fitting clothing and avoiding irritation to the area can help minimize discomfort and potential complications.

4. Education and Awareness: Understanding the nature of HPV and its implications during pregnancy can alleviate anxiety. It’s important to stay informed about the condition and any potential risks.

In conclusion, while the pathology report indicates the presence of viral warts, the atypical presentation means that ongoing monitoring and consultation with healthcare providers are essential. The focus should be on managing any symptoms and ensuring the health and safety of both the mother and the fetus throughout the pregnancy. If any new symptoms arise or if there are concerns about the lesion, it is crucial to seek medical advice promptly.

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