Stage IV Lung Cancer: Survival Rates and Treatment Options - Pulmonology

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Stage IV lung cancer


Hello Dr.
Ke, my father is 60 years old and is currently receiving chemotherapy for advanced lung cancer at Tri-Service General Hospital.
His condition initially involved metastasis to the brain, resulting in right-sided hemiplegia.
After one or two sessions of radiation therapy, he has regained some function in his right side.
He is currently on the third cycle of the first course of chemotherapy, and according to his attending physician, there are still five more cycles to go.
I would like to ask, since the attending physician has indicated that there is no chance of cure for terminal patients and that chemotherapy can only help maintain his current condition, what is the approximate survival duration for patients who receive treatment compared to those who do not? I would appreciate your response, Dr.
Ke.

Fenny, 30~39 year old female. Ask Date: 2002/06/17

Dr. Ke Zhengchang reply Pulmonology


Hello: In stage IV lung cancer with brain metastasis, the average survival is typically only three to six months.
Therefore, even with chemotherapy, the average additional survival time is only extended by two to four weeks.
Family members should be psychologically prepared.
Ke Zhengchang, June 18, 2002.

Reply Date: 2002/06/17

More Info


Understanding Stage IV lung cancer, particularly in the context of your father's situation, involves recognizing both the prognosis and the treatment options available. Stage IV lung cancer is characterized by the spread of cancer beyond the lungs to other parts of the body, such as the brain, which is particularly concerning in your father's case.
Survival rates for Stage IV lung cancer can vary significantly based on several factors, including the patient's overall health, the specific characteristics of the cancer, and the treatments being administered. Generally, the prognosis for Stage IV lung cancer is poor, with median survival rates typically ranging from 6 to 12 months. However, some patients may live longer, especially if they respond well to treatment. In your father's case, the fact that he has undergone radiation therapy and is currently receiving chemotherapy may provide some additional time, although the primary goal of these treatments is often to manage symptoms and maintain quality of life rather than to cure the disease.

In terms of survival with and without treatment, studies suggest that patients who receive chemotherapy may experience a modest extension of life compared to those who do not receive any treatment. For instance, while untreated patients may have a median survival of around 3 to 6 months, those receiving chemotherapy might extend their survival by an additional 2 to 4 weeks on average. However, these figures can vary widely, and individual responses to treatment can differ greatly.

It's also important to consider the side effects and the impact of treatment on quality of life. Chemotherapy can cause significant side effects, including fatigue, nausea, and a weakened immune system, which can affect the patient's overall well-being. Therefore, discussions with the healthcare team about the goals of treatment, potential benefits, and the patient's preferences are crucial.

In your father's case, the fact that he has shown some recovery in his right side after radiation therapy is a positive sign, indicating that he may still have some functional capacity and quality of life to maintain. The continuation of chemotherapy, as advised by his oncologist, is likely aimed at controlling the disease and alleviating symptoms.

In summary, while Stage IV lung cancer presents a challenging prognosis, treatment options such as chemotherapy can provide some benefit in terms of extending survival and improving quality of life. It is essential to maintain open communication with the healthcare team to understand the treatment plan, manage expectations, and make informed decisions about care moving forward. Additionally, supportive care, including palliative care services, can play a vital role in enhancing comfort and addressing any psychosocial needs during this difficult time.

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