How to Lower GOT and GPT Levels: Tips for Liver Health

GOT 48, GPT 71?

Hello Dr.
Chen, my liver enzyme levels are GOT 48 and GPT 71.
I do not have hepatitis B or C.
I am being treated at Asia University Hospital.
I previously took medication for hyperthyroidism for about a year, but I am now well and no longer need to take it.
My uric acid level is 8.4.
The GOT level is significantly affected; whenever I drink alcohol, it rises to 48 within two weeks.
After about a month without alcohol, it decreases to 38.
The GPT remains consistently at 71.
I work long hours, exceeding 10 hours a day, and I exercise regularly.
My sleep duration is about 5 hours.
Could you please advise me on how to lower my GOT and GPT levels? Besides the hyperthyroidism medication, I am also taking a multivitamin.
My height is 180 cm and my weight is 79 kg.
Thank you for your guidance.

Chen Junliang, 40~49 year old female. Ask Date: 2015/09/07

Dr. Chen Qifeng reply Gastroenterology and Hepatology

Hello, aside from hepatitis B and C, another cause of abnormal liver function is fatty liver...
Of course, there are also other less common causes.
Therefore, it is essential to rely on abdominal ultrasound and some blood tests for diagnosis.
If it is indeed fatty liver, the metabolic issues must be addressed first.
Sincerely, Dr.
Chen Chi-Feng, Attending Physician, Department of Gastroenterology, Taoyuan General Hospital, Ministry of Health and Welfare.

Reply Date: 2015/09/07

More Info

To lower your GOT (AST) and GPT (ALT) levels, it's essential to adopt a holistic approach that encompasses lifestyle modifications, dietary changes, and regular monitoring of your liver health. Elevated liver enzymes can indicate liver cell damage or inflammation, and while you have ruled out hepatitis B and C, other factors may still contribute to your elevated levels.

1. Limit Alcohol Consumption
Given that your GOT levels significantly increase after alcohol consumption, it's crucial to limit or eliminate alcohol from your diet. Alcohol can be toxic to liver cells, leading to inflammation and elevated enzyme levels. If you choose to drink, moderation is key—this typically means no more than one drink per day for women and two for men.

2. Healthy Diet
A balanced diet plays a vital role in liver health. Here are some dietary recommendations:
- Reduce Sugar and Refined Carbohydrates: High sugar intake can lead to fatty liver disease. Limit sugary snacks, sodas, and white bread.

- Increase Fruits and Vegetables: These are rich in antioxidants and can help reduce inflammation. Aim for a variety of colors to ensure a range of nutrients.

- Healthy Fats: Incorporate sources of omega-3 fatty acids, such as fish, walnuts, and flaxseeds, which can help reduce liver fat levels.

- Lean Proteins: Opt for lean meats, poultry, fish, beans, and legumes. These can help repair liver cells.

- Stay Hydrated: Drink plenty of water to help your liver function optimally.

3. Regular Exercise
You mentioned that you engage in regular exercise, which is excellent. Aim for at least 150 minutes of moderate aerobic activity per week, such as brisk walking, swimming, or cycling. Exercise helps maintain a healthy weight and can reduce liver fat.

4. Weight Management
If you are overweight or obese, losing even a small percentage of your body weight can significantly improve liver health. Aim for a gradual weight loss of 1-2 pounds per week through a combination of diet and exercise.

5. Sleep Hygiene
You noted that you only get about 5 hours of sleep per night. Lack of sleep can contribute to metabolic issues and liver stress. Aim for 7-9 hours of quality sleep each night. Establish a regular sleep schedule, create a relaxing bedtime routine, and make your sleep environment comfortable.

6. Avoid Unnecessary Medications
Be cautious with over-the-counter medications and supplements, as some can be hepatotoxic. Always consult with your healthcare provider before starting any new medication or supplement, especially if you have elevated liver enzymes.

7. Regular Monitoring
Continue to have regular check-ups with your healthcare provider. Monitoring your liver enzymes periodically will help track your progress and make necessary adjustments to your lifestyle or treatment plan.

8. Consider Professional Guidance
If your liver enzymes remain elevated despite lifestyle changes, consider consulting a hepatologist or a nutritionist specializing in liver health. They can provide tailored advice and may suggest further testing to rule out other underlying conditions.

Conclusion
By implementing these lifestyle changes, you can significantly improve your liver health and lower your GOT and GPT levels. Remember, it’s essential to be patient, as changes in liver enzyme levels may take time to reflect your efforts. Always keep an open line of communication with your healthcare provider to ensure you are on the right track.

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