Eye Drops: Safety, Ingredients, and Benefits for Eye Health - Ophthalmology

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Hello, Doctor: My father has to use a computer for long hours due to work, which often leads to eye fatigue and redness.
In addition to using a warm eye mask for hot compresses, I have also purchased eye drops to help relieve discomfort and moisturize his eyes.
However, the pharmacist mentioned that frequent use of eye drops containing vasoconstrictors should be avoided.
Therefore, I would like to ask:
1.
What potential effects could frequent use of eye drops containing vasoconstrictors have? Additionally, from an ophthalmologist's perspective, is there a more precise definition of "frequent"?
2.
Is "tetrahydrozoline hydrochloride" the same ingredient as "tetrahydrozoline HCl"? When I asked the pharmacist, he told me that the latter is the vasoconstrictor, while the former is not, which contradicts the information I found online, so I would like to confirm.
3.
Some eye drops emphasize the addition of Vitamin B6 or Vitamin A.
I know these are beneficial for the eyes, but when applied as eye drops, can these ingredients actually be absorbed by the eye's structure and provide their benefits?
I hope you can clarify these three questions.
Thank you very much.
Wishing you all the best.

Natasha, 20~29 year old female. Ask Date: 2015/09/21

Dr. Gao Pilin reply Ophthalmology


Hello Natasha:
1.
Vasoconstrictors are used to constrict the blood vessels in your eyes, which temporarily reduces redness.
However, it is best to avoid using them unless necessary, and it is recommended not to exceed four times a day.

2.
Hydrochloride refers to HCL, so the two are the same.

3.
It is better to obtain vitamins through diet, as the effectiveness of eye drops is limited.

Taiwan E-Hospital Puzi Hospital Ophthalmology: Monday to Friday from 8:00 AM to 12:00 PM and Wednesday afternoons from 1:00 PM to 4:30 PM.
We hope to have the opportunity to serve you.

Gao Pilin

Reply Date: 2015/09/21

More Info


When it comes to eye drops, understanding their ingredients, safety, and benefits is crucial, especially for individuals who spend long hours in front of screens. Your father's situation, where he experiences eye fatigue and redness due to prolonged computer use, is common in today's digital age. Let's address your questions systematically.

1. Frequent Use of Vasoconstrictor Eye Drops: Vasoconstrictor eye drops, such as those containing tetrahydrozoline, work by narrowing the blood vessels in the eye, which temporarily reduces redness. However, frequent use can lead to a phenomenon known as "rebound redness." This occurs when the blood vessels dilate again after the medication wears off, potentially leading to a cycle of dependency on the drops. Over time, excessive use can also cause irritation, dryness, and even worsen the underlying condition that caused the redness in the first place. As a general guideline, it is advisable not to use these drops more than four times a day. If your father finds he needs to use them more frequently, it may be worth consulting an eye care professional to explore underlying issues or alternative treatments.

2. Tetrahydrozoline Hydrochloride vs. Tetrahydrozoline HCl: Both terms refer to the same active ingredient. "Tetrahydrozoline hydrochloride" is the full name of the compound, while "tetrahydrozoline HCl" is simply a shorthand version. The "HCl" denotes that it is in its hydrochloride form, which is a common way to present many medications to enhance their solubility and stability. Therefore, there is no difference in efficacy or function between the two; they are indeed the same substance.

3. Absorption of Vitamins in Eye Drops: Eye drops that contain vitamins such as B6 or A are often marketed for their potential benefits to eye health. However, the effectiveness of these vitamins when applied topically as eye drops is limited. The eye's anatomy is designed to protect itself from foreign substances, and while some ingredients can be absorbed, the concentration and bioavailability of vitamins in eye drops may not be sufficient to provide significant therapeutic benefits. Oral supplementation or dietary intake of these vitamins is generally more effective for overall eye health. For instance, vitamin A is crucial for maintaining good vision and eye health, but it is best obtained through a balanced diet rich in fruits, vegetables, and fish rather than relying solely on eye drops.

In addition to these considerations, it's essential to adopt good eye care practices, especially for those who spend extended periods on screens. The 20-20-20 rule is a helpful guideline: every 20 minutes, take a 20-second break to look at something 20 feet away. This practice can help reduce eye strain and fatigue. Additionally, ensuring proper lighting, maintaining a comfortable distance from screens, and using artificial tears or lubricating eye drops (without vasoconstrictors) can help alleviate discomfort.

In conclusion, while eye drops can provide temporary relief for symptoms like redness and dryness, they should be used judiciously, especially those containing vasoconstrictors. It's always best to consult with an eye care professional for personalized advice and to explore other options for managing eye health, particularly for someone who frequently uses a computer. Regular eye examinations are also vital to monitor any changes in eye health and to adjust treatment as necessary.

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