Can a PSA Level of 1.13 Indicate Remaining Prostate Cancer? - Oncology

Share to:

Is it possible to have malignant tumors with a post-prostate cancer PSA level of 1.13?


On June 29, 2015, the PSA level was 17.4.
A biopsy on August 3 of the same year confirmed the presence of malignant tumors, specifically prostate cancer.
On September 4, the PSA level increased to 25.78.
On September 8, hormone therapy with Androcur was initiated.
On October 6, a monthly hormone injection was administered along with oral hormone tablets, and a blood test for PSA was conducted.
Radiation therapy is scheduled for early November.
After being diagnosed with prostate cancer, the patient also adopted dietary changes and natural therapies involving fruits and vegetables.
On October 15, the PSA level report showed a reduction to 1.13.
Is prostate cancer still present? Can an MRI be performed before radiation therapy to confirm this?

pengser, 60~69 year old female. Ask Date: 2015/10/16

Dr. Chen Yunfang reply Oncology


Hello: The prostate-specific antigen (PSA) level is used for monitoring, not for diagnosing prostate cancer.
The diagnosis of prostate cancer relies on pathological biopsy; if cancer is present, it is confirmed.
Unless you have undergone surgical removal, you cannot say there are no cancer cells remaining.
Even if the PSA level is very low, there may still be cancer cells present.
Your current PSA level of 1.13 is within the normal range, indicating good control.
However, many individuals who have completed radiation therapy and are also on hormone therapy maintain their PSA levels below 0.1, so I still recommend that you undergo radiation therapy.
As for undergoing an MRI, I do not recommend it, as it will not impact your current treatment decisions.
Thank you!

Reply Date: 2015/10/16

More Info


The question of whether a PSA level of 1.13 indicates the presence of remaining prostate cancer is complex and requires a nuanced understanding of prostate cancer management and the role of PSA (Prostate-Specific Antigen) testing.
PSA is a protein produced by both normal and malignant cells of the prostate gland, and it is commonly used as a biomarker to monitor prostate cancer. However, it is important to note that PSA levels can fluctuate due to various factors, including benign prostatic hyperplasia (BPH), prostatitis (inflammation of the prostate), and even recent sexual activity. Therefore, while a high PSA level can raise suspicion for prostate cancer, it is not definitive for diagnosis.

In your case, the initial PSA levels were significantly elevated, indicating a serious concern for prostate cancer, which was confirmed by biopsy. Following treatment with hormone therapy, the PSA level dropped to 1.13, which is within the normal range for most laboratories. This reduction in PSA is a positive sign and suggests that the treatment may be effectively controlling the disease. However, it does not definitively indicate that all cancer cells have been eradicated.
The presence of cancer cells can persist even when PSA levels are low. The only way to confirm the absence of cancer after treatment is through surgical removal of the prostate (radical prostatectomy) or through imaging studies that can detect residual disease. In your situation, since you are scheduled for radiation therapy, it is crucial to continue with the planned treatment, as radiation can help target any remaining cancer cells that may not be detectable through PSA levels alone.

Regarding the use of MRI (Magnetic Resonance Imaging) before radiation therapy, it can be a useful tool in assessing the prostate and surrounding tissues. MRI can help identify any suspicious areas that may warrant further investigation or treatment. However, the decision to perform an MRI should be made in consultation with your healthcare provider, considering the timing and the potential impact on your treatment plan.

In summary, while a PSA level of 1.13 is encouraging and suggests that the cancer may be under control, it does not guarantee that there are no remaining cancer cells. Continuous monitoring and adherence to the treatment plan, including radiation therapy, are essential. Additionally, discussing the potential for MRI with your healthcare team can provide further clarity on the status of your prostate health and guide your treatment decisions. Always remember that open communication with your healthcare providers is key to managing your health effectively.

Similar Q&A

Understanding Elevated PSA Levels: Risks of Prostate Cancer

Hello Dr. Du: My father is 61 years old and underwent partial laser resection for benign prostatic hyperplasia four years ago. Recently, he has been experiencing pain after urination, and blood tests revealed a PSA level of 18. What is the likelihood that this indicates prostate ...


Dr. Du Shixi reply Urology
Hello: For reference, it is essential to discuss with a clinical physician. In cases of painful urination, it is crucial to first diagnose whether there is inflammation. Such inflammatory conditions can potentially escalate significantly, and treatment should be prioritized. If i...

[Read More] Understanding Elevated PSA Levels: Risks of Prostate Cancer


Is a Rising PSA Level a Strong Indicator of Prostate Cancer Risk?

Dear Dr. Du, I am 51 years old. During my health check-ups, my PSA levels were consistently around 1.4 until 2014. However, last year, the level increased to 2.6, and this year it has risen to 3.56. I won't be able to schedule an appointment until mid-November, and I am qui...


Dr. Du Shixi reply Urology
Hello: The prostate index is a reference and should not be solely relied upon for diagnosis. Additionally, clinically, the index may fluctuate slightly depending on certain conditions of the prostate. You mentioned that these are numbers from a health check; if possible, I recomm...

[Read More] Is a Rising PSA Level a Strong Indicator of Prostate Cancer Risk?


Understanding PSA Levels: What a 5.1 Result Means for Men's Health

1. Hello, doctor. I recently had a health check-up. My cancer screening values for AFP and CEA (EIA) are within the reference range. ENBA-1 IgA is negative, but my PSA level is 5.1. Is there any correlation among these four values? 2. I had some urinary difficulties recently du...


Dr. Liu Jianting reply Urology
PSA: 5.1! This is somewhat confusing. The normal value is generally considered to be < 4, but a value > 4 may indicate: 1. Benign Prostatic Hyperplasia (BPH) 2. Prostatitis 3. Prostate Cancer. However, this is just a reference and not absolute. Further tests should be condu...

[Read More] Understanding PSA Levels: What a 5.1 Result Means for Men's Health


Understanding Elevated PSA Levels: Prostate Cancer or Benign Enlargement?

Prostate cancer is a slowly progressing cancer. In April of this year, my first PSA test showed a level of 5.08. By early August, the second test had risen to 6.88 (with free PSA at 23%). By the end of August, the third test showed a level of 7.88 (with free PSA at 16.5%). Additi...


Dr. Jian Weihong reply Urology
Hello: During my visit to the medical center, I heard the physician's advice that certain factors can affect PSA levels, but it is important to be cautious.

[Read More] Understanding Elevated PSA Levels: Prostate Cancer or Benign Enlargement?


Related FAQ

Elevated Psa Levels

(Urology)

Prostate Cancer

(Urology)

Prostate Cancer

(Oncology)

Psa

(Urology)

Prostate-Specific Antigen

(Urology)

Benign Prostatic Hyperplasia

(Urology)

Lump

(Urology)

Cea Index

(Oncology)

Lump

(Oncology)

Hpv Testing

(Urology)