Is it possible to have malignant tumors with a post-prostate cancer PSA level of 1.13?
On June 29, 2015, the PSA level was 17.4.
A biopsy on August 3 of the same year confirmed the presence of malignant tumors, specifically prostate cancer.
On September 4, the PSA level increased to 25.78.
On September 8, hormone therapy with Androcur was initiated.
On October 6, a monthly hormone injection was administered along with oral hormone tablets, and a blood test for PSA was conducted.
Radiation therapy is scheduled for early November.
After being diagnosed with prostate cancer, the patient also adopted dietary changes and natural therapies involving fruits and vegetables.
On October 15, the PSA level report showed a reduction to 1.13.
Is prostate cancer still present? Can an MRI be performed before radiation therapy to confirm this?
pengser, 60~69 year old female. Ask Date: 2015/10/16
Dr. Chen Yunfang reply Oncology
Hello: The prostate-specific antigen (PSA) level is used for monitoring, not for diagnosing prostate cancer.
The diagnosis of prostate cancer relies on pathological biopsy; if cancer is present, it is confirmed.
Unless you have undergone surgical removal, you cannot say there are no cancer cells remaining.
Even if the PSA level is very low, there may still be cancer cells present.
Your current PSA level of 1.13 is within the normal range, indicating good control.
However, many individuals who have completed radiation therapy and are also on hormone therapy maintain their PSA levels below 0.1, so I still recommend that you undergo radiation therapy.
As for undergoing an MRI, I do not recommend it, as it will not impact your current treatment decisions.
Thank you!
Reply Date: 2015/10/16
More Info
The question of whether a PSA level of 1.13 indicates the presence of remaining prostate cancer is complex and requires a nuanced understanding of prostate cancer management and the role of PSA (Prostate-Specific Antigen) testing.
PSA is a protein produced by both normal and malignant cells of the prostate gland, and it is commonly used as a biomarker to monitor prostate cancer. However, it is important to note that PSA levels can fluctuate due to various factors, including benign prostatic hyperplasia (BPH), prostatitis (inflammation of the prostate), and even recent sexual activity. Therefore, while a high PSA level can raise suspicion for prostate cancer, it is not definitive for diagnosis.
In your case, the initial PSA levels were significantly elevated, indicating a serious concern for prostate cancer, which was confirmed by biopsy. Following treatment with hormone therapy, the PSA level dropped to 1.13, which is within the normal range for most laboratories. This reduction in PSA is a positive sign and suggests that the treatment may be effectively controlling the disease. However, it does not definitively indicate that all cancer cells have been eradicated.
The presence of cancer cells can persist even when PSA levels are low. The only way to confirm the absence of cancer after treatment is through surgical removal of the prostate (radical prostatectomy) or through imaging studies that can detect residual disease. In your situation, since you are scheduled for radiation therapy, it is crucial to continue with the planned treatment, as radiation can help target any remaining cancer cells that may not be detectable through PSA levels alone.
Regarding the use of MRI (Magnetic Resonance Imaging) before radiation therapy, it can be a useful tool in assessing the prostate and surrounding tissues. MRI can help identify any suspicious areas that may warrant further investigation or treatment. However, the decision to perform an MRI should be made in consultation with your healthcare provider, considering the timing and the potential impact on your treatment plan.
In summary, while a PSA level of 1.13 is encouraging and suggests that the cancer may be under control, it does not guarantee that there are no remaining cancer cells. Continuous monitoring and adherence to the treatment plan, including radiation therapy, are essential. Additionally, discussing the potential for MRI with your healthcare team can provide further clarity on the status of your prostate health and guide your treatment decisions. Always remember that open communication with your healthcare providers is key to managing your health effectively.
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