Cheek and Mouth Pain: Possible Neurological Causes - Neurology

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Pain in the corner of the mouth and cheek?


Recently, I have been experiencing intermittent sharp pain in my cheek, especially in the evening after brushing my teeth.
Initially, I thought it was a cavity, but before I could see a dentist, I noticed that the pain shifted to the inside of my mouth, accompanied by a burning sensation and occasional sores at the corners of my mouth.
I previously suffered a head injury in a car accident and underwent an electromyography (EMG) test at Kaohsiung Medical University, which indicated damage at the C5 level.
Could this be related? Additionally, I came across a website where a user mentioned that a neurosurgeon from a hospital in Eastern Taiwan suggested that cheek pain could be a precursor to amyotrophic lateral sclerosis (ALS) or Parkinson's disease.
Is this true?

Andy, 20~29 year old female. Ask Date: 2015/11/10

Dr. Lan Shengxing reply Neurology


Dear Andy, the likelihood of Parkinson's disease or amyotrophic lateral sclerosis (ALS) is relatively low, especially considering your age, so there is no need for concern.
The intermittent burning pain in your cheeks may suggest trigeminal neuralgia.
I recommend that you consult a neurologist for further evaluation.

Reply Date: 2015/11/10

More Info


Understanding cheek and mouth pain can be complex, especially when considering potential neurological causes. Your symptoms, including intermittent sharp pain in the cheek and a burning sensation in the mouth, warrant a thorough evaluation. Given your history of head trauma from a car accident and previous findings of C5 nerve root involvement, it is plausible that your current symptoms could be related to nerve damage or irritation stemming from that injury.

The trigeminal nerve, which is responsible for sensation in the face, including the cheeks and mouth, can be affected by various factors, including trauma. Damage to this nerve can lead to conditions such as trigeminal neuralgia, characterized by sudden, severe facial pain. This pain can be triggered by activities like brushing your teeth, which may explain the timing of your symptoms. Additionally, if there is any irritation or inflammation in the area, it could exacerbate the pain.

The burning sensation you describe in your mouth, along with the appearance of sores at the corners of your mouth, could also indicate a condition known as angular cheilitis, which is often associated with nutritional deficiencies, particularly vitamin B12 or iron. This condition can lead to pain and discomfort, especially when eating or speaking.

Regarding your concern about the possibility of serious neurological conditions such as amyotrophic lateral sclerosis (ALS) or Parkinson's disease, it is essential to understand that while these conditions can present with facial pain or discomfort, they typically have additional symptoms that would be more pronounced. For instance, ALS often involves muscle weakness and atrophy, while Parkinson's disease is characterized by tremors, rigidity, and bradykinesia (slowness of movement). If you are experiencing only facial pain without these additional symptoms, it is less likely that you are at the early stages of these diseases.

However, it is crucial to consult with a neurologist who can perform a comprehensive evaluation, including a detailed history, physical examination, and possibly imaging studies or further nerve conduction studies. They can help determine whether your symptoms are related to your previous injury, a neurological condition, or another underlying issue.

In summary, your symptoms of cheek and mouth pain could be related to nerve involvement from your past injury, possibly exacerbated by other factors such as nutritional deficiencies or local inflammation. It is essential to seek medical advice from a specialist who can provide a tailored diagnosis and treatment plan. Early intervention can often lead to better outcomes, so do not hesitate to pursue further evaluation.

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