Abnormalities in blood test immune markers?
Hello Doctor, I underwent a surgical abortion on November 6th (the embryo's heartbeat stopped at eight weeks), and on November 7th, I had blood drawn for immune testing.
The abnormal result highlighted in red is: anti-thrombin III, with a result of 78.0%.
I see that the reference range in the report is 79.4 to 112.01.
1.
What does this item indicate?
2.
I am unsure if this abnormal result will affect future pregnancies.
Should I seek treatment or have my blood tested again? Thank you, Doctor.
Miss Lin, 30~39 year old female. Ask Date: 2015/11/12
Dr. Zeng Guosen reply Internal Medicine
Hello, user: The issue regarding anti-thrombin III generally falls within the field of hematology in clinical practice.
To ensure a complete and accurate response to your question, I recommend consulting a hematology specialist.
Thank you.
Reply Date: 2015/11/12
More Info
Anti-Thrombin III (AT III) is a crucial protein in the body that helps regulate blood clotting. It works by inhibiting thrombin and other clotting factors, thereby preventing excessive blood clot formation. A normal level of AT III is essential for maintaining a balance in the coagulation system, and abnormal levels can lead to either an increased risk of thrombosis (blood clots) or bleeding disorders.
In your case, your AT III level is reported at 78.0%, which is below the reference range of 79.4% to 112.01%. This indicates a mild deficiency in AT III. It is important to note that a single abnormal result does not necessarily indicate a significant health issue, especially if there are no accompanying symptoms or a history of clotting disorders.
1. Impact of Abnormal AT III Levels on Pregnancy: While a deficiency in AT III can increase the risk of thrombosis, its direct impact on pregnancy can vary. In some cases, it may contribute to complications such as recurrent pregnancy loss or placental insufficiency, particularly if there are other risk factors present. However, your situation involves a recent abortion, and it is essential to differentiate whether the AT III level is a contributing factor to the loss or a separate issue altogether.
2. Timing of the Test: Since you had the blood test the day after your abortion, it is possible that the stress of the procedure and the hormonal changes associated with it could temporarily affect your AT III levels. This means that the result may not accurately reflect your baseline level. It is advisable to repeat the test after a few weeks to see if the levels normalize.
3. Need for Treatment or Follow-Up: Given that your AT III level is only slightly below the normal range and considering that you have not experienced recurrent pregnancy loss, immediate treatment may not be necessary. However, it is essential to discuss your results with your healthcare provider. They may recommend monitoring your levels over time, especially if you plan to conceive again. If you have a history of clotting disorders or other risk factors, your doctor may consider further evaluation or treatment options.
4. General Recommendations: It is crucial to maintain regular follow-ups with your healthcare provider, especially after a pregnancy loss. They can provide personalized advice based on your overall health, family history, and any other relevant factors. Additionally, lifestyle modifications such as maintaining a healthy weight, staying active, and avoiding smoking can help improve your overall vascular health.
In summary, while your AT III level is slightly low, it may not pose an immediate risk, especially in the context of a recent abortion. It is advisable to have a follow-up test and discuss your results with your healthcare provider to determine the best course of action for your reproductive health moving forward.
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