Can I Breastfeed While Taking Hydroxychloroquine Sulfate 200mg? - Internal Medicine

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Is it safe to breastfeed while taking Hydroxychloroquine sulfate 200mg?


I have Sjögren's syndrome and suspected systemic lupus erythematosus.
I am currently taking Hydroxychloroquine sulfate 200mg.
Can I breastfeed? Thank you.

Peipei, 20~29 year old female. Ask Date: 2015/11/13

Dr. Zeng Guosen reply Internal Medicine


Hello, user: This medication can be excreted in breast milk, with concentrations in breast milk being significantly lower than the therapeutic levels in the mother's bloodstream.
To date, there have been no reported cases of adverse reactions due to breastfeeding.
However, since infants may be more sensitive to this medication, it is still recommended to use it with caution.
This medication should only be used when the potential benefits outweigh the risks.
It is advisable to discuss this with your treating physician before making a decision on whether to continue its use.
Thank you for your question.

Reply Date: 2015/11/13

More Info


When considering whether to breastfeed while taking Hydroxychloroquine Sulfate 200mg, it is essential to weigh the benefits of breastfeeding against the potential risks associated with the medication. Hydroxychloroquine is an antimalarial drug that is also used to treat autoimmune diseases such as systemic lupus erythematosus (SLE) and rheumatoid arthritis.
Research indicates that Hydroxychloroquine is generally considered safe for use during breastfeeding. The drug has a low oral bioavailability, and only a small amount is excreted in breast milk. According to the American Academy of Pediatrics, Hydroxychloroquine is classified as "usually compatible with breastfeeding." This classification suggests that the benefits of breastfeeding while on this medication typically outweigh any potential risks to the infant.

However, it is crucial to monitor the infant for any adverse effects, especially if the mother is taking higher doses or if the infant has any underlying health issues. Some studies have shown that the levels of Hydroxychloroquine in breast milk are low, and the amount ingested by a breastfeeding infant is significantly less than the therapeutic dose used for treating malaria or autoimmune conditions.
In your case, since you have Sjögren's syndrome and suspected systemic lupus erythematosus, continuing your medication is vital for managing your health. Hydroxychloroquine can help control symptoms and prevent flares of your condition, which is essential for your overall well-being.
If you decide to breastfeed while on Hydroxychloroquine, here are some recommendations:
1. Consult Your Healthcare Provider: Always discuss your plans with your healthcare provider, who can provide personalized advice based on your specific health situation and the health of your baby.

2. Monitor Your Baby: Keep an eye on your infant for any unusual symptoms, such as excessive drowsiness, irritability, or feeding difficulties. If you notice any concerning signs, consult your pediatrician.

3. Consider Timing: If you have concerns about the timing of your medication relative to breastfeeding, you might consider taking Hydroxychloroquine just after breastfeeding. This way, the levels of the drug in your milk will be lower when your baby feeds next.

4. Stay Informed: Keep yourself updated on any new research regarding Hydroxychloroquine and breastfeeding. Medical guidelines can change as new studies emerge.

5. Discuss Alternatives: If you have concerns about Hydroxychloroquine, discuss alternative treatments with your healthcare provider. However, remember that managing your autoimmune condition is crucial for your health, which indirectly affects your ability to care for your baby.

In conclusion, breastfeeding while taking Hydroxychloroquine sulfate 200mg is generally considered safe, but it is essential to maintain open communication with your healthcare provider and monitor your infant for any potential side effects. Your health and the health of your baby are both paramount, and finding a balance that works for both of you is key.

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