Persistent Corneal Edema After Cataract Surgery: Next Steps and Options - Ophthalmology

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Postoperative corneal edema persists without resolution?


Hello, Doctor: It has been over three months since my cataract surgery, and I am still experiencing corneal edema.
The doctor examined me and noted that there is a small area of degeneration in the central endothelial cells.
The corneal edema may not improve, and I was advised to continue medication for management.
I would like to ask, if this condition does not improve after six months, should I go to a major hospital in Tainan for a corneal examination? I understand that there is a procedure for transplanting corneal endothelial cells.
How high is the risk associated with this procedure? Additionally, could you please let me know which hospital in Tainan, Chi Mei or Cheng Da, offers this type of surgery?

len, 40~49 year old female. Ask Date: 2015/11/14

Dr. Wang Zhishun reply Ophthalmology


Hello, you can visit the ophthalmology department at Cheng Kung University for an evaluation.
Although the surgery for corneal endothelial cell transplantation has advanced significantly, it still carries a much higher risk compared to cataract surgery.

Reply Date: 2015/11/14

More Info


Persistent corneal edema following cataract surgery can be a challenging condition, particularly when it involves endothelial cell degeneration. In your case, it has been three months since your surgery, and the presence of corneal edema suggests that the corneal endothelium may not be functioning optimally. The endothelial cells are crucial for maintaining corneal clarity by regulating fluid balance within the cornea. When these cells are damaged or degenerate, fluid can accumulate, leading to edema and visual disturbances.


Next Steps and Options
1. Continued Medical Management: As your doctor suggested, continuing with the prescribed medications is essential. These may include hypertonic saline drops, which help draw fluid out of the cornea, or other medications aimed at reducing inflammation or promoting healing.

2. Monitoring: If your condition does not improve within the next few months, it is advisable to seek further evaluation. A follow-up appointment with your ophthalmologist is crucial to assess the progression of the edema and the health of your corneal endothelium.

3. Referral to a Corneal Specialist: If the edema persists after six months, a referral to a specialized corneal clinic or a tertiary care center, such as a large hospital in Tainan, would be prudent. These centers often have advanced diagnostic tools and treatment options available.

4. Corneal Endothelial Transplantation: If conservative management fails and the edema significantly affects your vision or quality of life, your doctor may discuss the option of a corneal endothelial transplant, also known as Descemet's Stripping Endothelial Keratoplasty (DSEK) or Descemet Membrane Endothelial Keratoplasty (DMEK). This procedure involves transplanting healthy endothelial cells from a donor cornea to replace the damaged cells in your eye.


Risks of Corneal Endothelial Transplantation
Corneal endothelial transplantation is generally considered safe, but like any surgical procedure, it carries risks. These may include:
- Rejection: The body may reject the donor tissue, leading to complications.

- Infection: As with any surgery, there is a risk of infection.

- Intraocular Pressure Changes: Surgery can affect the pressure within the eye, which may require monitoring and management.

- Visual Outcomes: While many patients experience improved vision, some may not achieve the desired results.


Hospitals in Tainan
In Tainan, both Chi Mei Medical Center and National Cheng Kung University Hospital (成大醫院) are reputable institutions that offer advanced ophthalmic care, including corneal surgeries. It would be beneficial to contact these hospitals directly to inquire about their specific capabilities regarding corneal endothelial transplantation and to schedule a consultation with a corneal specialist.


Conclusion
In summary, persistent corneal edema after cataract surgery warrants careful monitoring and potentially further intervention if conservative measures do not yield improvement. Seeking a second opinion or referral to a specialized center can provide you with more options and a clearer understanding of your condition. It is essential to maintain open communication with your healthcare provider and discuss any concerns you may have about your treatment plan.

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