Laboratory Report
Hello Doctor, the examination results from 11/06 are as follows:
Fasting Blood Sugar: 126
Hemoglobin A1c: 6.8
Triglycerides: 87
Total Cholesterol: 198
LDL: 154
HDL: 38
Creatinine: 1.0
BUN: 19
Direct Bilirubin: 0.1
Total Bilirubin: 0.6
Alkaline Phosphatase: 29
Question 1: GOT and GPT are low, and GPT is less than GOT.
Yesterday, an ultrasound showed moderate fatty liver on the left side and severe fatty liver on the right side, with gallbladder polyps.
What does this information indicate, and what further tests should I undergo to confirm liver function?
Question 2: What does the elevated LDL and low HDL indicate?
Question 3: Is there any other unknown information from the above numbers? Thank you!
Wu Zhi-xian, 60~69 year old female. Ask Date: 2015/11/24
Dr. Chen Qifeng reply Gastroenterology and Hepatology
Hello,
1.
Liver function tests and ultrasound interpretation should take into account the history of alcohol consumption and hepatitis to provide a comprehensive assessment.
2.
Total cholesterol levels are not high, but LDL is elevated and HDL is low, indicating poor dietary sources of cholesterol (predominantly from animal fats).
3.
Glycated hemoglobin levels need to be monitored.
Sincerely,
Dr.
Chi-Feng Chen, Attending Physician, Department of Gastroenterology, Taoyuan Hospital, Ministry of Health and Welfare.
Reply Date: 2015/11/24
More Info
Understanding your liver and cholesterol test results is crucial for managing your health, especially given the findings you've shared. Let's break down the key components of your test results and what they mean.
1. Liver Function Tests (LFTs)
Your liver function tests, specifically the levels of GOT (AST) and GPT (ALT), are important indicators of liver health. In your case, you mentioned that both GOT and GPT are low, with GPT being less than GOT. Typically, elevated levels of these enzymes indicate liver inflammation or damage. However, low levels can sometimes be misleading. They may suggest that there is no active liver damage, but in the context of your ultrasound findings of fatty liver (steatosis), it indicates that the liver is under stress due to fat accumulation.
The ultrasound results showing "left mild fatty liver" and "right severe fatty liver" suggest that you have a significant amount of fat in your liver, which can lead to non-alcoholic fatty liver disease (NAFLD). This condition can progress to more severe liver issues, including inflammation (steatohepatitis) and fibrosis. Given your ultrasound findings and the presence of gallbladder polyps, further evaluation is warranted. You may want to consider additional tests such as:
- Liver Biopsy: This can provide a definitive diagnosis regarding the degree of inflammation and fibrosis.
- FibroScan: A non-invasive test that assesses liver stiffness, which correlates with fibrosis.
- Viral Hepatitis Testing: To rule out viral causes of liver disease, especially if you have a history of liver issues.
2. Cholesterol Levels
Your lipid profile shows elevated LDL (154 mg/dL) and low HDL (38 mg/dL). LDL is often referred to as "bad cholesterol" because high levels can lead to plaque buildup in arteries, increasing the risk of cardiovascular diseases. Conversely, HDL is known as "good cholesterol" because it helps remove LDL from the bloodstream.
The combination of high LDL and low HDL is concerning and suggests an increased risk for cardiovascular issues. This could be influenced by dietary habits, physical activity levels, and body weight. Given your recent weight gain of 10 kg, it’s essential to focus on lifestyle modifications:
- Diet: Adopt a heart-healthy diet rich in fruits, vegetables, whole grains, and lean proteins while reducing saturated fats and sugars.
- Exercise: Regular physical activity can help improve HDL levels and lower LDL levels.
- Weight Management: Losing weight can significantly improve your lipid profile and liver health.
3. Other Considerations
Your blood glucose levels indicate prediabetes (fasting blood sugar of 126 mg/dL and HbA1c of 6.8%). This is a critical finding as it places you at risk for developing type 2 diabetes. Managing your blood sugar through diet, exercise, and possibly medication is essential.
Additionally, your bilirubin levels (total and direct) are within normal limits, which is a positive sign, indicating that there is no significant obstruction in the bile ducts or severe liver dysfunction at this time.
Conclusion
In summary, your test results indicate several areas of concern, particularly regarding liver health and cholesterol levels. It is crucial to follow up with your healthcare provider to discuss these findings in detail and to consider further testing to assess liver function and potential damage. Implementing lifestyle changes focused on diet, exercise, and weight management will be vital in improving your overall health and mitigating the risks associated with fatty liver and dyslipidemia. Regular monitoring of your liver function and lipid levels will also be important as you make these changes.
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