Amenorrhea: Why Your Period Might Be Missing and What to Do - Obstetrics and Gynecology

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MC has not come for a long time?


Since last July, I haven't had my period, and I'm not pregnant.
My health is good, so why hasn't it come? What should I do?

andy, 20~29 year old female. Ask Date: 2002/07/04

Dr. Peng Yiguo reply Obstetrics and Gynecology


Based on the information provided, prior to July of last year, menstruation was likely normal, indicating secondary amenorrhea.
If there is no pregnancy, a progestin injection or oral progestin can be administered for three to four days, followed by observation for any uterine bleeding (i.e., onset of menstruation).
If uterine bleeding occurs, it may be advisable to check thyroid function through a blood test or to assess for any nipple discharge.
If menstruation does not resume after the progestin treatment, it is best to consult a gynecologist.
Additionally, factors such as being underweight or overweight, as well as significant mental stress (from work, career, or academic pressures), can contribute to the absence of menstruation, and these aspects should be addressed to improve overall health and alleviate stress.

Reply Date: 2002/07/04

More Info


Amenorrhea, or the absence of menstruation, can be a concerning issue for many individuals, particularly when it persists for an extended period, such as in your case since July of last year. Understanding the underlying causes of amenorrhea is crucial for determining the appropriate course of action.
Firstly, it’s important to differentiate between the two types of amenorrhea: primary and secondary. Primary amenorrhea refers to the absence of menstruation by the age of 16, while secondary amenorrhea is when a person who has previously menstruated stops having periods for three months or more. Given that you mentioned your menstrual cycle has not returned since July, it seems you are experiencing secondary amenorrhea.

There are several potential causes for secondary amenorrhea, and they can be broadly categorized into physiological, hormonal, and lifestyle factors:
1. Hormonal Imbalances: The menstrual cycle is regulated by a complex interplay of hormones. Conditions such as polycystic ovary syndrome (PCOS), thyroid disorders (hypothyroidism or hyperthyroidism), and hyperprolactinemia (elevated levels of prolactin) can disrupt this balance and lead to amenorrhea.
2. Stress and Mental Health: Psychological factors, including stress, anxiety, and depression, can significantly impact your menstrual cycle. The body’s response to stress can alter hormone levels, leading to missed periods.

3. Weight Changes: Significant weight loss or gain can affect your menstrual cycle. Low body weight, often seen in eating disorders like anorexia or bulimia, can lead to amenorrhea. Conversely, obesity can also disrupt hormonal balance and lead to irregularities.

4. Excessive Exercise: Intense physical activity, especially in athletes or those who engage in rigorous training, can lead to a condition known as hypothalamic amenorrhea. This occurs when the body perceives excessive exercise as a stressor, leading to hormonal changes that suppress menstruation.

5. Chronic Illness: Certain chronic health conditions, such as diabetes or celiac disease, can also affect menstrual regularity.

6. Medications: Some medications, particularly hormonal contraceptives, can lead to amenorrhea. If you have recently started or stopped any medications, this could be a contributing factor.

Given that you have ruled out pregnancy and are in good health, it is advisable to consult a healthcare provider for a thorough evaluation. They may recommend a series of tests, including blood tests to check hormone levels, a pelvic ultrasound to assess the ovaries and uterus, and possibly other diagnostic procedures to determine the underlying cause of your amenorrhea.

In the meantime, consider the following steps:
- Monitor Your Symptoms: Keep a detailed record of your menstrual cycle, any accompanying symptoms (such as weight changes, stress levels, or exercise habits), and any medications you are taking. This information can be invaluable for your healthcare provider.

- Manage Stress: Engage in stress-reducing activities such as yoga, meditation, or mindfulness practices. These can help alleviate some of the psychological factors that may be contributing to your amenorrhea.

- Evaluate Lifestyle Factors: Assess your diet and exercise routine. Ensure you are maintaining a balanced diet and not over-exercising, as both can impact your menstrual health.

- Seek Professional Help: If your period does not return soon, or if you experience other concerning symptoms (such as severe pain, significant weight changes, or mood swings), it’s essential to seek medical advice promptly.

In summary, while amenorrhea can be distressing, understanding its potential causes and seeking appropriate medical guidance can help you address the issue effectively. Remember, your health is paramount, and taking proactive steps can lead to better outcomes.

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