Abnormal White Blood Cells and Epithelial Cells in Urine - Urology

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Understanding abnormal white blood cells (WBC) and epithelial cells in urine can be crucial for diagnosing potential health issues. In a urinalysis, the presence of white blood cells and epithelial cells can indicate various conditions, and it’s essential to interpret these findings in the context of your overall health and any symptoms you may be experiencing.

White Blood Cells (WBC) in Urine:
The presence of white blood cells in urine is often a sign of inflammation or infection. Normal urine typically contains very few or no white blood cells. When WBC counts are elevated, it can suggest conditions such as:
1. Urinary Tract Infection (UTI): This is one of the most common reasons for increased WBC in urine. Symptoms may include frequent urination, burning sensation during urination, and cloudy or foul-smelling urine.


2. Kidney Infection (Pyelonephritis): This is a more severe infection that can cause back pain, fever, and chills, in addition to the urinary symptoms.

3. Interstitial Cystitis: A chronic condition that causes bladder pressure, bladder pain, and sometimes pelvic pain.

4. Other Inflammatory Conditions: Conditions like glomerulonephritis or lupus can also lead to elevated WBC in urine.

In your case, if you are experiencing frequent urination, it would be prudent to consider the possibility of a urinary tract infection or another underlying issue. A healthcare provider may recommend further testing, such as a urine culture, to identify any bacterial infection.

Epithelial Cells in Urine:
Epithelial cells are shed from the lining of the urinary tract. A small number of epithelial cells in urine is generally considered normal. However, an increased number can indicate:
1. Infection or Inflammation: Similar to WBC, a higher count of epithelial cells can suggest irritation or infection in the urinary tract.

2. Contamination: Sometimes, epithelial cells can be present due to contamination from the skin or vaginal area during urine collection.

3. More Serious Conditions: In some cases, a significant increase in epithelial cells may indicate more serious conditions such as bladder cancer or other malignancies, especially if accompanied by other abnormal findings.

Given that your urinalysis showed abnormalities in both WBC and epithelial cells, it is essential to follow up with your healthcare provider. They may recommend additional tests or a repeat urinalysis to monitor these findings and determine the underlying cause.

Frequent Urination:
Frequent urination, especially at night (nocturia), can be caused by various factors, including:
- Infections: As mentioned, UTIs can lead to increased urgency and frequency.

- Diabetes: Both diabetes mellitus and diabetes insipidus can cause increased urination.

- Prostate Issues: In men, an enlarged prostate can lead to urinary frequency.

- Medications: Certain medications, especially diuretics, can increase urination.

- Bladder Conditions: Overactive bladder syndrome can also cause frequent urination.

In conclusion, the presence of abnormal WBC and epithelial cells in your urine suggests that further evaluation is necessary to rule out infections or other underlying conditions. It is advisable to consult with a healthcare professional who can provide a comprehensive assessment based on your symptoms and laboratory findings. They may suggest lifestyle modifications, dietary changes, or medications depending on the diagnosis. Regular follow-ups and monitoring are essential to ensure your urinary health is maintained.