Preparing for Pregnancy: Medication Safety and Guidelines - Obstetrics and Gynecology

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Pregnancy Preparation - Medication


Hello Doctor: My wife and I are planning to conceive, but I recently learned that she has been using a dermatology-prescribed acne medication, "Fulosin Cream (2%)".
I am concerned about whether this will have any impact on her ability to conceive.
If it does have an effect, how long should she stop using the medication before trying to get pregnant? Additionally, I have been experiencing eczema due to stress and my dermatologist has prescribed both oral and topical corticosteroids.
Will this affect our plans to conceive? If so, how long should I stop using these medications before we can try to conceive? Thank you!

Xiao Zheng, 20~29 year old female. Ask Date: 2015/12/01

Dr. Lin Wenbin reply Obstetrics and Gynecology


Using Fuhuo New only for a short term and not taking oral medications should not have a significant impact on preparing for pregnancy.
What medications is the male partner taking? You can consult the prescribing physician on-site.

Reply Date: 2015/12/01

More Info


When preparing for pregnancy, it's crucial to consider the safety of any medications that you or your partner may be taking. The effects of medications on fertility and fetal development can vary significantly based on the type of drug, the dosage, and the timing of exposure during pregnancy.

Fulosin Cream (Fulosin 2%)
Fulosin Cream is primarily used for treating acne and contains a topical retinoid. Topical retinoids are generally considered safer than oral retinoids during pregnancy, but they are still classified as Category C by the FDA. This means that while animal reproduction studies have shown an adverse effect on the fetus, there are no adequate and well-controlled studies in pregnant women. Therefore, it is advisable to discontinue the use of Fulosin Cream at least one month before trying to conceive to minimize any potential risks.

Corticosteroids for Eczema
Regarding the corticosteroids prescribed for your eczema, the safety of these medications during pregnancy largely depends on the potency of the steroid and the route of administration. Topical corticosteroids, when used in moderation and as directed, are generally considered safe during pregnancy. However, high-potency steroids or prolonged use can lead to systemic absorption, which may pose risks to both the mother and the fetus.
If you are using topical corticosteroids, it is recommended to stop using them at least one month before trying to conceive, especially if they are high-potency formulations. If you are on oral corticosteroids, it is essential to consult with your healthcare provider to evaluate the necessity of the medication and discuss alternative treatments that may be safer during the preconception period.


General Guidelines for Medication Use Before Pregnancy
1. Consult Healthcare Providers: Always discuss any medications you or your partner are taking with your healthcare provider. They can provide guidance on the safety of specific medications and recommend alternatives if necessary.

2. Timing: If a medication is deemed unsafe for pregnancy, it is generally advisable to stop taking it at least one month before trying to conceive. This allows the body to clear the medication and reduces the risk of potential effects on fertility or fetal development.

3. Consider Non-Pharmacological Alternatives: For conditions like acne or eczema, consider non-pharmacological treatments or lifestyle changes that may help manage symptoms without the need for medications.

4. Preconception Counseling: Engaging in preconception counseling with a healthcare provider can help identify any potential risks associated with current medications and provide a comprehensive plan for a healthy pregnancy.

5. Monitor Health: Both partners should focus on maintaining overall health through a balanced diet, regular exercise, and managing stress, which can positively influence fertility and pregnancy outcomes.

In summary, while topical medications like Fulosin Cream may pose some risks, they are generally safer than systemic medications. Corticosteroids, particularly when used topically, can also be safe if used appropriately. Always consult with healthcare professionals to ensure that any medications are safe for both partners while preparing for pregnancy.

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