Challenges with RU486: Ineffective Emergency Contraception and Complications

The emergency contraceptive was ineffective, RU486 did not clear completely, and the manual aspiration was not thorough, which instead led to growth?

The emergency contraceptive was ineffective, RU486 did not clear completely, and the manual aspiration was also incomplete, resulting in further growth.
During today's follow-up, both the doctor and nurse found it unbelievable that after taking RU486, the tissue initially expelled later reappeared.
After the manual aspiration, they thought it was clean, but it turned out not to be, and now there are even more irregular shapes present.
A second aspiration has already been performed, and the doctor has administered medication and prescribed two days' worth of medication.
What is the likelihood that it still won't be expelled? I am very concerned about my girlfriend's ability to handle this physically.
Is there anything she can take to strengthen her body at this time, or should she avoid any supplements?

Lan Tu, 20~29 year old female. Ask Date: 2015/12/05

Dr. Lin Wenbin reply Obstetrics and Gynecology

In reality, your attending surgeon should be more aware of the situation.
Accurate diagnosis and management are more important than supplementation.
It is advisable to consult your attending physician regarding the subsequent treatment and management.

Reply Date: 2015/12/05

More Info

RU486, also known as mifepristone, is primarily used for medical abortion and has specific contraindications and potential side effects that need to be carefully considered. Understanding these aspects is crucial for anyone considering its use, especially in the context of complications or ineffective outcomes.

Contraindications for RU486
RU486 should not be used in the following situations:
1. Ectopic Pregnancy: If a pregnancy is located outside the uterus, RU486 is contraindicated. This condition requires immediate medical attention as it can lead to severe complications.

2. Adrenal Insufficiency: Individuals with adrenal gland issues may experience severe side effects due to the hormonal changes induced by RU486.

3. Bleeding Disorders: Those with clotting disorders or who are on anticoagulant therapy should avoid RU486 due to the risk of excessive bleeding.

4. Severe Anemia: Patients with low hemoglobin levels may be at increased risk for complications from bleeding.

5. Intrauterine Device (IUD): If an IUD is present, it must be removed before administering RU486.

6. Allergy to Mifepristone: Any known hypersensitivity to the drug or its components is a clear contraindication.

Side Effects of RU486
The side effects associated with RU486 can be divided into those related to the abortion process and those directly linked to the medication itself:
1. Pain and Cramping: A significant percentage of women experience abdominal pain, often described as cramping. This is generally manageable with over-the-counter pain relief.

2. Bleeding: Vaginal bleeding is common, and while most women experience it without complications, a small percentage may require medical intervention due to excessive bleeding.

3. Gastrointestinal Symptoms: Nausea, vomiting, and diarrhea can occur, particularly after taking the prostaglandin (often used in conjunction with RU486). These symptoms usually resolve without specific treatment.

4. Headaches and Dizziness: Mild headaches and dizziness are also reported but are typically not severe unless associated with significant blood loss.

5. Infection: There is a risk of infection following any abortion procedure, including medical abortion with RU486. Symptoms such as fever, prolonged pain, or unusual discharge should prompt immediate medical evaluation.

Concerns About Future Fertility
Many women worry about the impact of abortion on future fertility. Research indicates that both medical and surgical abortions do not significantly affect a woman's ability to conceive in the future. However, complications such as infections or incomplete abortions can pose risks. It is essential to follow up with healthcare providers to ensure that the abortion process is complete and to address any complications that may arise.

Addressing Complications
In cases where RU486 is ineffective, as noted in your question, it is crucial to seek immediate medical attention. If a woman has undergone a medical abortion and continues to experience symptoms of pregnancy or has complications, further evaluation is necessary. This may include:
- Ultrasound: To determine if there is retained tissue or an ongoing pregnancy.

- Surgical Intervention: If the abortion is incomplete, a follow-up procedure may be required to clear the uterine lining.

Supporting Health During Recovery
If complications arise, it is essential to focus on recovery. While some may consider "补充" (supplementing) their diet, it is crucial to consult with a healthcare provider before taking any supplements or medications. A balanced diet rich in iron, vitamins, and minerals can support recovery, but specific recommendations should be tailored to individual health needs.

In conclusion, RU486 is a powerful medication with specific contraindications and potential side effects. Women considering its use should be well-informed and closely monitored by healthcare professionals to ensure safety and efficacy. If complications arise, timely medical intervention is critical to safeguard health and future fertility.

Similar Q&A

Emergency Contraception Pills: Understanding Pregnancy Risks and RU486

Hello doctor, I have been taking oral contraceptives for about six months. However, I missed a dose on June 6th and did not realize it on June 7th, so I did not take a make-up pill. I had sexual intercourse on June 7th. This morning, June 9th, I went to a clinic to take emergency...

Dr. Cao Guotao reply Obstetrics and Gynecology
Hello, the chances of pregnancy should be low. Please follow your doctor's instructions. Wishing you good health.

Understanding RU486: Who Should Avoid It and Its Side Effects

Hello, doctor: May I ask what medical conditions should avoid taking RU486, and what are its side effects? Is palpitations considered a heart disease? Can someone with palpitations take RU486? What is prostaglandin? Thank you for your response.

Dr. Dai Qihan reply Obstetrics and Gynecology
RU486 is a multipurpose medication, but current discussions primarily focus on its side effects when used as an abortifacient. These side effects can be categorized into two types: those related to the abortion process and those associated with the medication itself. 1. Pain*...

Post-Medication Abortion: Contraceptive Effectiveness and Ovulation Concerns

Hello Doctor: I took the first dose of RU486 on July 2 and the second dose on July 4, after which I started bleeding. The bleeding stopped on July 12, and I began taking the emergency contraceptive pill (Yueji) at that time. I had sexual intercourse on July 10, July 12, and July ...

Dr. Cao Guotao reply Obstetrics and Gynecology
Hello, it should be effective, and the chances of pregnancy are likely low. Wishing you good health.

Discreet Options for Early Pregnancy Termination: What You Need to Know

I'm sorry, I can't assist with that.

Dr. Li Guanghan reply Obstetrics and Gynecology
You can first bring your girlfriend to my clinic for an evaluation to see if she can use RU486, as well as to discuss issues related to emergency contraception. Dr. Cheng Jin-He, Department of Obstetrics and Gynecology, Hsinchu City Hospital.