Breast Cancer Treatment and Recurrence Risks - Oncology

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What is the treatment duration for breast cancer?


Hello Doctor, my mother is 58 years old and has just undergone a lumpectomy for breast cancer this year.
The tumor was 1.3 cm in size, and there was no lymph node metastasis.
She is currently receiving chemotherapy with a regimen that includes small red berries, and she has completed her second cycle.
The third cycle is scheduled for December 16.
Since her pathology report shows strong positivity for HER2, this morning I noticed a small hard lump near the surgical site.
I would like to ask: 1.
Is there a possibility of recurrence during chemotherapy? 2.
Could the lump inside the surgical site be a scar tissue? Since her attending physician is currently out of the country, I would like to hear other doctors' opinions to reassure my mother.
Thank you.

Ayu, 30~39 year old female. Ask Date: 2015/12/09

Dr. Chen Yunfang reply Oncology


Hello: Based on your description, your mother's postoperative pathological staging should be stage I, which is considered early stage.
In my experience, it is very rare to encounter or hear of someone who relapses during postoperative chemotherapy; it is truly uncommon! Once your attending physician returns to the country, please have them examine her to determine if there is any recurrence, which would provide more reassurance.
Thank you!

Reply Date: 2015/12/09

More Info


Breast cancer treatment and the associated risks of recurrence are critical topics that require careful consideration, especially in the context of your mother's recent surgery and ongoing chemotherapy. Given the details you've provided, let's address your questions systematically.

1. Is it possible for breast cancer to recur during chemotherapy?
Yes, it is possible for breast cancer to recur during chemotherapy, although the likelihood varies depending on several factors, including the type and stage of cancer, the effectiveness of the treatment, and individual patient characteristics. In your mother's case, she has undergone a lumpectomy for a tumor measuring 1.3 cm with no lymph node involvement, which is generally a favorable prognostic indicator. However, HER2-positive breast cancers can be more aggressive, and the risk of recurrence can be higher compared to other types. The chemotherapy regimen, which includes the use of agents like "小紅莓" (likely referring to a specific chemotherapy drug), is designed to target any remaining cancer cells and reduce the risk of recurrence. Continuous monitoring and follow-up imaging are crucial during this period to detect any signs of recurrence early.

2. Could the lump near the surgical site be scar tissue?
The lump you described near the surgical site could potentially be scar tissue, also known as fibrosis, which is a common occurrence after surgery. Surgical procedures often lead to the formation of scar tissue as the body heals. However, it is essential to differentiate between benign scar tissue and a possible recurrence of cancer. The characteristics of the lump, such as its size, texture, and any associated symptoms (like pain or changes in skin appearance), can provide clues. It is advisable to have this lump evaluated by a healthcare professional, preferably through imaging studies like an ultrasound or MRI, to determine its nature. If it is indeed scar tissue, it may resolve over time, but if there are concerns about recurrence, a biopsy may be warranted.

In summary, while there is a possibility of recurrence during chemotherapy, the absence of lymph node involvement and the early stage of your mother's cancer are positive factors. The lump near the surgical site could be scar tissue, but it is essential to have it evaluated to rule out any malignancy. Communication with your mother's healthcare team is vital, and if her primary physician is unavailable, seeking a second opinion or consultation with another oncologist can provide additional reassurance and clarity. Regular follow-ups and monitoring are crucial in managing her treatment and addressing any concerns that arise during this period.

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