HIV Transmission: Debunking Myths About White Blood Cells - Internal Medicine

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Regarding white blood cells?


Hello, doctor.
I would like to ask you about the information I found online regarding HIV infection.
It states that the virus can directly invade human cells, which significantly increases the risk of infection.
However, when I asked the school doctor, he said that cells are not the primary route of HIV transmission.
Which one is correct? (Previously, I had a shaved head injury, and I am concerned that a customer who looked suspicious might have infected me with HIV if he had folliculitis fluid on his head.
According to Dr.
Luo's article from the Heart Valley, it should not be infectious.
Lastly, I would like to ask if there are live infected white blood cells in folliculitis fluid.
If so, how many are typically present?)

Yiwenzhe, 10~19 year old female. Ask Date: 2015/12/15

Dr. Zeng Guosen reply Internal Medicine


Hello, internet user: HIV is transmitted through intimate contact with bodily fluids or blood.
The main routes of transmission are sexual intercourse, blood transfusions, and sharing drug injection needles.
The risk of infection from folliculitis fluid on a shaved head is relatively low.
It is recommended that you consult an infectious disease specialist.
Thank you for your question.

Reply Date: 2015/12/15

More Info


Understanding HIV transmission is crucial in dispelling myths and ensuring that individuals are informed about the actual risks involved. The primary mode of HIV transmission is through direct contact with certain body fluids from an infected person, including blood, semen, vaginal fluids, rectal fluids, and breast milk. The most common routes of transmission are through unprotected sexual intercourse, sharing needles, and from mother to child during childbirth or breastfeeding.

To address your question regarding the role of white blood cells (WBCs) in HIV transmission, it is important to clarify that while white blood cells are part of the immune system and play a role in fighting infections, they are not the primary means by which HIV is transmitted. HIV primarily infects CD4+ T cells, which are a type of white blood cell, but the virus itself is not transmitted through the cells in a way that would increase the risk of infection simply by contact with WBCs. Instead, the virus is present in the bodily fluids mentioned earlier, and it is the virus itself that must enter the bloodstream or mucous membranes for infection to occur.

Regarding your concern about the potential for infection from contact with folliculitis (inflammation of hair follicles) fluid, it is essential to understand that the risk of HIV transmission from such fluids is extremely low. Folliculitis fluid typically does not contain a significant viral load of HIV, especially if the fluid is not fresh and has been exposed to the environment for some time. HIV is a fragile virus that does not survive long outside the human body; it becomes inactive within minutes once exposed to air. Therefore, if the fluid you are concerned about was not fresh and had dried, the likelihood of it containing viable HIV is negligible.

In terms of the presence of live infected white blood cells in folliculitis fluid, it is unlikely that such a fluid would contain a substantial number of viable HIV-infected cells. Even if white blood cells were present, the concentration of HIV would be significantly lower than in blood or other high-risk fluids. Moreover, the transmission of HIV requires a direct pathway into the bloodstream, such as through open wounds or mucous membranes, which is not typically the case with superficial skin conditions like folliculitis.

To summarize, the key points regarding HIV transmission are as follows:
1. Transmission Routes: HIV is primarily transmitted through sexual contact, sharing needles, and from mother to child. Casual contact with infected fluids, especially if they are not fresh, poses a minimal risk.

2. Role of White Blood Cells: While HIV targets CD4+ T cells (a type of white blood cell), the virus is transmitted through bodily fluids, not through the cells themselves.

3. Environmental Stability of HIV: HIV does not survive long outside the body. Once exposed to air, it becomes inactive quickly, reducing the risk of transmission from dried fluids.

4. Low Risk from Folliculitis: The risk of contracting HIV from contact with folliculitis fluid is extremely low, particularly if the fluid is not fresh and there are no open wounds or mucous membranes involved.

If you have ongoing concerns about potential exposure to HIV or any other infections, it is advisable to consult with a healthcare professional or an infectious disease specialist who can provide personalized advice and testing if necessary.

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