Syphilis Issues
Doctor, may I ask you a question? I had a syphilis antibody test (RPR/VDRL and TPHA) 38 days after sexual intercourse, and both results were negative.
Then, 48 days after that sexual encounter, I tested for VDRL antibodies again, and the result was also negative.
Now, it has been 82 days since the sexual encounter.
Should I get tested for syphilis again?
nick, 10~19 year old female. Ask Date: 2015/12/15
Dr. Xu Weikai reply Urology
Nick: Hello, it's not necessary.
However, it is best to check for other sexually transmitted infections such as HIV and Hepatitis B.
If there are any unclear points, feel free to ask again, and we can discuss and research further.
Answers from the internet should only be used as a reference; if necessary, you should seek medical attention at a healthcare facility.
This response is provided by Dr.
Hsu Wei-Kai, Director of the Urology Department, Taitung Hospital, Ministry of Health and Welfare.
Reply Date: 2015/12/15
More Info
When it comes to testing for syphilis after engaging in sexual activity, particularly after a period of 82 days, it's important to consider several factors, including the timing of the tests, the nature of the sexual activity, and the specific tests used.
In your case, you underwent testing for syphilis (RPR/VDRL and TPHA) at 38 days and again at 48 days post-exposure, both of which returned negative results. The RPR (Rapid Plasma Reagin) and VDRL (Venereal Disease Research Laboratory) tests are non-treponemal tests that can indicate the presence of syphilis, while the TPHA (Treponema pallidum hemagglutination assay) is a treponemal test that confirms the infection. Generally, these tests are most reliable when conducted after the window period, which is typically around 6 weeks for non-treponemal tests and can be longer for treponemal tests.
The window period for syphilis testing is crucial because it refers to the time after exposure during which the tests may not yet detect the infection. For syphilis, the window period can vary, but it is generally recommended to wait at least 6 weeks after potential exposure for the most accurate results. Since you have already tested negative at 38 and 48 days, you are likely in a good position regarding syphilis infection.
However, the recommendation to get tested again at 82 days is not strictly necessary based on the negative results you've already received, especially since they were conducted within the recommended window period. That said, if you have any new symptoms or concerns, or if you believe you may have been exposed to syphilis again, it would be prudent to consult with a healthcare provider for further evaluation and possibly retesting.
Additionally, it is wise to consider testing for other sexually transmitted infections (STIs) as well, such as HIV, hepatitis B, and hepatitis C, especially if you have engaged in high-risk behaviors. The guidelines for HIV testing suggest that testing should be done at least 2-4 weeks after potential exposure, with follow-up testing at 3 months for conclusive results.
In summary, while your previous negative tests for syphilis at 38 and 48 days post-exposure are reassuring, if you have ongoing concerns or symptoms, it is always best to consult with a healthcare professional. They can provide personalized advice and determine if further testing is warranted based on your specific situation. Remember, regular STI testing is an important aspect of sexual health, especially after engaging in high-risk behaviors.
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