Esophageal Reflux: Managing Symptoms and Treatment Concerns - Gastroenterology and Hepatology

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Gastroesophageal reflux disease (GERD)


Hello Dr.
Tsai, I have a history of gastroesophageal reflux disease (GERD) for 10 years and have been regularly seeing a doctor at National Taiwan University Hospital for endoscopies and medication.
My symptoms include excessive stomach acid and frequent belching.
Today, on April 21, I had surgery on my toe and took a lot of antibiotics.
In mid-May, I caught a cold with yellow phlegm, and the doctor prescribed me medication for mycoplasma, which I have been taking for almost two weeks.
Since then, my stomach has been slow to improve, and I am belching easily.

In the past, if I experienced frequent belching, it indicated that my reflux was starting again, and I would take pantoprazole, which would gradually improve my condition in about 10 days.
However, this time, after taking it for a long time, there has been no improvement.
On December 15, I underwent an endoscopy, and the doctor said I had excessive stomach acid and that there was a slight abrasion near my stomach and duodenum.
He mentioned it was not an ulcer but still prescribed pantoprazole for two months.
I switched to pantoprazole from rabeprazole two years ago.
The doctor was busy with many patients, so I didn’t ask many questions.
Fortunately, there is the Taiwan e-Hospital to help explain some of my concerns.
Thank you.
My GERD was originally classified as Grade A, but after the endoscopy on December 15, it changed to Grade B due to the abrasion.
If the abrasion heals, can I return to Grade A? Is the abrasion related to my frequent use of antibiotics? (Because doctors in rural areas often prescribe antibiotics to patients.) Or is it caused by excessive stomach acid?
If I have excessive stomach acid, will it worsen the abrasion? I am very worried.
Currently, if I have an abrasion, I should avoid taking antibiotics during a cold, correct? What does it mean for there to be an abrasion near the stomach and duodenum? I don’t understand.
Please help me clarify my concerns, Dr.
Tsai.
Thank you very much.

Tian Shi Kai Ma, 50~59 year old female. Ask Date: 2015/12/18

Dr. Cai Anshun reply Gastroenterology and Hepatology


Hello: (1) If the reflux improves, esophagitis can be reversible, so it is possible to return to grade A.
(2) I believe the so-called "skin breakdown" likely refers to gastritis or duodenitis, which can have many causes, not solely related to antibiotics.
(3) If excessive gastric acid is not improved, it may lead to gastritis or duodenitis that cannot heal.
(4) For a cold, it is important to determine the cause; viral infections do not require antibiotics.
Changhua Hospital cares about your health.
Dr.
Tsai An-shun.

Reply Date: 2015/12/18

More Info


Esophageal reflux, commonly known as gastroesophageal reflux disease (GERD), is a chronic condition that can significantly impact a person's quality of life. Your history of GERD, along with the recent complications following your surgery and antibiotic use, raises several important points regarding symptom management and treatment strategies.


Understanding Your Condition
1. Esophageal Damage and Classification: The classification of your esophagitis has progressed from LA grade A to grade B, indicating a worsening of your condition. This change is often due to the presence of erosions or breaks in the esophageal lining, which can be exacerbated by factors such as increased gastric acid production, dietary choices, and the use of medications like antibiotics. The "breaking of the skin" you mentioned refers to these erosions, which can lead to inflammation and discomfort.

2. Impact of Antibiotics: Antibiotics can disrupt the normal flora of the gastrointestinal tract, potentially leading to increased gastric acid production or changes in digestion that can exacerbate GERD symptoms. If you have been prescribed antibiotics frequently, it may contribute to your current symptoms. It’s essential to discuss with your healthcare provider the necessity of antibiotics and explore alternatives when possible.

3. Acid Production and Erosions: Excessive gastric acid can indeed worsen esophageal erosions. If your stomach is producing too much acid, it can lead to further irritation of the esophagus, making it more susceptible to damage. This cycle can perpetuate your symptoms and lead to more severe complications if not managed effectively.


Management Strategies
1. Proton Pump Inhibitors (PPIs): You mentioned using medications like NEXIUM (esomeprazole) and耐適恩 (pantoprazole). These medications are effective in reducing gastric acid production and can help heal the esophagus over time. It’s important to follow your doctor’s recommendations regarding the duration of PPI therapy, especially since you have experienced a worsening of symptoms. Generally, PPIs may be prescribed for several months to allow for healing, but long-term use should be monitored due to potential side effects, including impacts on calcium absorption and bone health.

2. Dietary Modifications: Implementing dietary changes can significantly help manage GERD symptoms. Avoiding trigger foods such as spicy dishes, caffeine, alcohol, and acidic foods can reduce the frequency of reflux episodes. Eating smaller, more frequent meals rather than large meals can also help minimize symptoms.

3. Lifestyle Adjustments: Elevating the head of your bed, avoiding lying down immediately after meals, and maintaining a healthy weight can also contribute to symptom relief. Additionally, managing stress through relaxation techniques or counseling can be beneficial, as stress can exacerbate GERD symptoms.

4. Monitoring and Follow-Up: Regular follow-up with your healthcare provider is crucial, especially given the changes in your condition. Your doctor may recommend repeat endoscopy to monitor the healing of the esophagus and to assess the severity of any ongoing damage. Typically, follow-up endoscopies are done every 6 to 12 months, depending on the severity of your condition and your response to treatment.

5. Antibiotic Use During Illness: If you are experiencing a respiratory infection, it is essential to discuss with your healthcare provider the risks and benefits of using antibiotics, especially if you have ongoing GERD symptoms. They may suggest alternative treatments that do not exacerbate your gastrointestinal issues.


Conclusion
In summary, managing GERD effectively requires a comprehensive approach that includes medication, dietary changes, lifestyle modifications, and regular monitoring. Your concerns about the progression of your condition and the impact of medications are valid and should be discussed with your healthcare provider. They can provide personalized recommendations based on your medical history and current symptoms. Remember, healing takes time, and with the right strategies in place, it is possible to improve your symptoms and quality of life.

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