Persistent Oral Ulcer: White Lesion Concerns and Cancer Risk - Dentistry

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Oral ulcer that does not heal and turns into a white patch?


Hello Doctor, about two weeks ago I bit my mouth while eating, which caused inflammation and pain.
I also developed ulcers on my tongue.
I used an oral ointment, and my tongue has healed, but the oral ulcer has not healed and still has a circular shape, although it is not painful.
I have noticed bleeding while brushing my teeth.
Currently, the wound is circular with a white area inside, resembling a white circle.
Could this be a sign of cancer? I am certain that this ulcer was caused by the bite, but now it has turned into a white circular shape.
Thank you for your response.

Xucheng, 20~29 year old female. Ask Date: 2015/12/20

Dr. Zeng Guanghui reply Dentistry


In the above situation, if the oral ulcer appears as a round white lesion and does not improve after 10 days, it is recommended to consult a dentist for further evaluation and treatment.

Reply Date: 2015/12/20

More Info


Persistent oral ulcers, particularly those that do not heal within two weeks, can indeed raise concerns about potential underlying issues, including the risk of malignancy. In your case, it sounds like you initially experienced a traumatic ulcer due to biting your cheek, which is a common occurrence. However, the fact that the ulcer has not healed and has developed a white lesion warrants further evaluation.

Oral white lesions can be classified into several categories, including leukoplakia, candidiasis, and other conditions. Leukoplakia, for instance, is a term used to describe white patches in the oral cavity that cannot be wiped away and may be associated with chronic irritation, such as from tobacco use or ill-fitting dentures. While leukoplakia can be benign, it has the potential to be a precancerous condition, especially if it persists.

In your situation, the round white lesion that has formed in the area of the original ulcer could be a sign of several things. It may represent a hyperplastic response to chronic irritation, or it could be indicative of a more serious condition, such as oral squamous cell carcinoma, particularly if it has not healed over an extended period. The presence of bleeding when brushing your teeth can also be a sign of inflammation or infection, which should not be overlooked.

It's important to note that not all persistent white lesions are cancerous. Conditions such as oral lichen planus, geographic tongue, or even fibromas can present as white patches or lesions in the mouth. However, the key factor here is the duration and persistence of the lesion. If it has been present for more than two weeks without improvement, it is advisable to seek further evaluation from a healthcare professional, preferably an oral surgeon or an ear, nose, and throat (ENT) specialist.

During the examination, the healthcare provider may perform a visual assessment and possibly a biopsy of the lesion to determine its nature. A biopsy is a critical step in diagnosing oral lesions, as it allows for histopathological examination to rule out malignancy or confirm a diagnosis.

In the meantime, it is essential to maintain good oral hygiene to prevent secondary infections and further irritation. Avoiding spicy, acidic, or abrasive foods may also help reduce discomfort. Additionally, if you smoke or use tobacco products, consider cessation, as these habits can exacerbate oral lesions and increase the risk of oral cancers.

In summary, while the initial cause of your ulcer was likely due to trauma, the persistence of the white lesion and associated symptoms necessitates a thorough evaluation to rule out any serious conditions, including cancer. Early detection and intervention are crucial in managing oral health issues effectively. Please consult with a healthcare professional as soon as possible for a comprehensive assessment and appropriate management.

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