Prolonged Side Effects of Motion Sickness Medication - Pharmacology

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Side effects of motion sickness medication?


Hello doctor, I recently took a cruise and used motion sickness medication for three days.
It has been three days since I disembarked, and I am still experiencing symptoms of dizziness, nausea, and gastrointestinal discomfort.
Is it normal for the side effects to last this long? Thank you!

Chelsey, 20~29 year old female. Ask Date: 2015/12/30

Dr. Lin Peiyu reply Pharmacology


Hello! If the symptoms persist without improvement, it is recommended that you visit a hospital for examination and diagnosis.

Reply Date: 2015/12/30

More Info


When it comes to the prolonged side effects of motion sickness medications, it's important to understand both the pharmacological properties of these drugs and how they interact with the body. Motion sickness medications, such as antihistamines (e.g., dimenhydrinate, meclizine) and anticholinergics (e.g., scopolamine), are commonly used to alleviate symptoms of nausea, vomiting, and dizziness associated with motion sickness. While these medications can be effective, they can also lead to side effects that may persist even after the medication has been discontinued.

The duration of side effects can vary significantly depending on several factors, including the specific medication used, the dosage, individual metabolism, and the duration of use. For instance, antihistamines can cause sedation, dizziness, and gastrointestinal disturbances. These side effects may linger for a few days after stopping the medication, particularly if the drug was taken for an extended period, such as three days in your case.

In your situation, experiencing dizziness, nausea, and gastrointestinal discomfort three days after discontinuing the medication could be attributed to several factors:
1. Half-Life of the Medication: The half-life of the medication determines how long it stays in your system. Some antihistamines have a longer half-life, which means they can remain in your body and continue to exert effects for several days after the last dose.

2. Individual Sensitivity: Some individuals may be more sensitive to the side effects of these medications. Factors such as age, overall health, and concurrent medications can influence how one reacts to motion sickness drugs.

3. Underlying Conditions: If you have any pre-existing conditions, such as vestibular disorders or gastrointestinal issues, these could exacerbate the symptoms you are experiencing.

4. Withdrawal Effects: In some cases, the body may react to the sudden cessation of medication, especially if it was used regularly. This can lead to a rebound effect where symptoms may temporarily worsen.

5. Psychological Factors: Anxiety or stress related to the experience of motion sickness can also contribute to lingering symptoms. The mind-body connection is powerful, and psychological factors can manifest as physical symptoms.

Given that you are experiencing these symptoms several days after stopping the medication, it is advisable to consult with a healthcare professional. They can assess your symptoms more thoroughly and determine whether they are indeed related to the medication or if there might be another underlying cause.
In the meantime, here are some general recommendations to help manage your symptoms:
- Stay Hydrated: Drink plenty of fluids to help alleviate nausea and support gastrointestinal health.

- Ginger or Peppermint: Natural remedies such as ginger tea or peppermint can help soothe nausea.

- Rest: Ensure you are getting adequate rest, as fatigue can exacerbate feelings of dizziness and nausea.

- Avoid Triggers: Stay away from strong odors, heavy meals, or other triggers that may worsen your symptoms.

In conclusion, while it is not uncommon for side effects from motion sickness medications to persist for a few days after discontinuation, it is essential to monitor your symptoms closely. If they continue or worsen, seeking medical advice is the best course of action to rule out any other potential issues and to receive appropriate care.

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