Persistent Warts: Why Treatments Aren't Working and What to Do - Dermatology

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My wart has been present for several years and hasn't healed?


Doctor, I have had warts on my hands for over three years, and they still haven't improved.
Neither cryotherapy nor topical treatments seem to work.
Every time there is some progress, they reappear after three to four weeks.
The cryotherapy is quite painful, so I mainly rely on topical treatments, but every time the skin peels off, it feels like there are more warts.
Can you please advise me on what might be happening?

3345678, 20~29 year old female. Ask Date: 2016/01/08

Dr. Li Yufen reply Dermatology


Hello: Regarding the causes and treatment of viral warts, you can refer to the article by Dr.
Lin Chi-bin from the Dermatology Expert Health Network at http://www.drskincare.com.tw/Qa/Detail.aspx?ID=52.
From the description, it seems that treatment may have been interrupted before complete healing, leading to a recurrence of viral warts in a short period.
It is recommended to continue treatment until the lesions are no longer visible to the naked eye, and then perform an additional cryotherapy session to reduce the chances of recurrence.
Additionally, for the usage of wart treatment solutions, you can refer to the educational article from the Dermatology Department of National Taiwan University Hospital at https://www.ntuh.gov.tw/derm/healthcareCenter/healthCenter/治疣液.aspx.
Thank you!

Reply Date: 2016/01/08

More Info


Persistent warts can be a frustrating and challenging condition to manage, especially when treatments seem ineffective. Warts are benign growths caused by the human papillomavirus (HPV), and they can appear on various parts of the body, including the hands. Here’s a comprehensive overview of why your treatments may not be working and what steps you can take to address the issue.


Understanding Warts and Their Persistence
1. Virus Characteristics: HPV has many different strains, and some are more resilient than others. The virus can remain dormant in the skin, making it difficult to completely eradicate the wart. Even after treatment, the virus can reactivate, leading to the recurrence of warts.

2. Immune Response: The effectiveness of wart treatments often depends on your immune system's ability to respond to the virus. Some individuals may have a weaker immune response, making it harder for their body to fight off the virus. This can lead to persistent warts despite various treatments.

3. Treatment Limitations: Common treatments like cryotherapy (freezing) and topical medications (like salicylic acid) can be effective, but they may not work for everyone. Cryotherapy can be painful, and while it may remove the visible wart, it does not always eliminate the underlying virus. Similarly, topical treatments can cause the wart to peel but may not penetrate deeply enough to eradicate the virus.

4. Misdiagnosis: In some cases, what appears to be a wart may actually be another skin condition, such as a seborrheic keratosis or a skin tag. If treatments are not working, it may be worth consulting a dermatologist for a thorough evaluation and accurate diagnosis.


What You Can Do
1. Consult a Dermatologist: If you haven't already, consider seeing a dermatologist who specializes in skin conditions. They can provide a more accurate diagnosis and recommend alternative treatments that may be more effective for your specific situation.

2. Explore Advanced Treatments: There are several advanced treatment options available for persistent warts, including:
- Laser Therapy: This method uses focused light to destroy the wart tissue and may be more effective for stubborn warts.

- Immunotherapy: This treatment involves stimulating your immune system to fight the virus. It can include topical treatments that provoke an immune response or injections of substances that enhance immune activity.

- Electrosurgery: This technique uses electrical currents to remove warts and may be effective for larger or more persistent warts.

3. Maintain Good Skin Care: Keeping the affected area clean and moisturized can help prevent further irritation and may support healing. Avoid picking at the warts, as this can lead to spreading the virus to other areas of your skin.

4. Consider Over-the-Counter Options: While you mentioned using topical medications, ensure you are using them correctly. Salicylic acid treatments should be applied consistently and may take several weeks to show results. Follow the instructions carefully, and consider using a higher concentration if recommended by a healthcare professional.

5. Boost Your Immune System: A healthy immune system can help your body fight off the virus more effectively. Ensure you are eating a balanced diet, getting regular exercise, and managing stress levels. Adequate sleep is also crucial for immune function.

6. Patience and Persistence: Warts can take time to resolve, and it may require a combination of treatments and approaches. Be patient and persistent with your treatment plan, and keep an open line of communication with your healthcare provider about what is and isn’t working.


Conclusion
Persistent warts can be a source of frustration, especially when treatments seem ineffective. Understanding the nature of warts, the limitations of current treatments, and exploring advanced options with a dermatologist can provide a pathway to resolution. Remember that patience and a proactive approach to your treatment can lead to better outcomes. If you continue to experience issues, do not hesitate to seek further medical advice.

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