Laryngopharyngeal Reflux: Symptoms and Diagnosis - Gastroenterology and Hepatology

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Pharyngeal acid reflux


Hello Doctor, I underwent a sleep study and found that I have a low AHI and high RDI, indicating nighttime respiratory resistance.
The doctor mentioned that one possible reason could be gastroesophageal reflux affecting the airway resistance.
I recall that I do experience nightly cough, excessive salivation, white phlegm, a sensation of something stuck in my throat, daily post-nasal drip, and morning throat pain, and sometimes I have difficulty expelling mucus.
However, if the acid reflux is affecting my throat, should I see a gastroenterologist or an ENT specialist? Additionally, could you please advise on what tools or methods are used for examination? Thank you.

Niming, 40~49 year old female. Ask Date: 2016/01/12

Dr. Yang Zhichao reply Gastroenterology and Hepatology


Dear Anonymous, it is recommended that you visit a hospital to consult with a gastroenterologist for an upper gastrointestinal endoscopy, which can assess gastroesophageal reflux disease (GERD).
Changhua Hospital cares about your health.

Reply Date: 2016/01/12

More Info


Laryngopharyngeal reflux (LPR) is a condition that occurs when stomach contents, including acid, flow back up into the throat and larynx. This can lead to a variety of symptoms, which you have described, including chronic cough, throat discomfort, excessive mucus production, and morning throat pain. Your experience of nighttime cough and difficulty swallowing can indeed be linked to LPR, as the reflux can irritate the lining of the throat and cause inflammation.


Symptoms of Laryngopharyngeal Reflux
Common symptoms of LPR include:
1. Chronic Cough: Often worse at night or upon waking.

2. Throat Discomfort: A sensation of a lump in the throat or persistent throat clearing.

3. Hoarseness: Changes in voice quality due to irritation of the vocal cords.

4. Sore Throat: Particularly in the morning, which can be attributed to acid exposure during sleep.

5. Excessive Mucus: A feeling of mucus accumulation in the throat, leading to frequent swallowing.

6. Difficulty Swallowing: This can occur due to inflammation or irritation in the throat.

7. Nasal Congestion: Postnasal drip can occur due to irritation from reflux.


Diagnosis of LPR
Diagnosis of LPR typically involves a combination of clinical evaluation and specific tests. Here are some common methods used to diagnose LPR:
1. Clinical History and Symptoms: A thorough history of symptoms is essential. Your symptoms, particularly the nighttime cough and throat discomfort, are suggestive of LPR.

2. Laryngoscopy: An ENT specialist may perform a laryngoscopy, which involves using a small camera to visualize the throat and larynx. This can help identify signs of inflammation or irritation caused by acid reflux.

3. pH Monitoring: This test measures the acidity in the esophagus and throat over a 24-hour period. It can help confirm the presence of acid reflux and correlate it with your symptoms.

4. Esophageal Manometry: This test measures the pressure and function of the esophagus and can help assess if there are any motility issues contributing to your symptoms.

5. Upper Endoscopy: If there are concerns about esophageal damage or other gastrointestinal issues, an upper endoscopy may be performed to visualize the esophagus and stomach directly.


Next Steps
Given your symptoms and the potential link to LPR, it would be advisable to consult both a gastroenterologist and an ENT specialist. The gastroenterologist can evaluate your gastrointestinal health and determine if there are any underlying issues such as gastroesophageal reflux disease (GERD) that may be contributing to your symptoms. The ENT specialist can assess the impact of reflux on your throat and voice.

In terms of treatment, lifestyle modifications are often recommended, including:
- Dietary Changes: Avoiding trigger foods such as spicy, fatty, or acidic foods.

- Eating Habits: Eating smaller meals and avoiding eating close to bedtime.

- Weight Management: Maintaining a healthy weight can reduce pressure on the stomach and lower the risk of reflux.

- Medications: Proton pump inhibitors (PPIs) or H2 blockers may be prescribed to reduce stomach acid production.

In conclusion, your symptoms are consistent with laryngopharyngeal reflux, and a multidisciplinary approach involving both gastroenterology and ENT specialists will provide the best pathway for diagnosis and management. It’s essential to address these symptoms early to prevent potential complications and improve your quality of life.

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