Medication Safety During Pregnancy: Managing Hypertension Concerns - Obstetrics and Gynecology

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Medication Issues During Pregnancy


Hello, Doctor.
I have chronic hypertension and have been consistently taking medication to manage it.
However, I am currently over two months pregnant (almost 10 weeks).
I previously informed my doctor about my plans to conceive, and among the antihypertensive medications recommended to me was "Coronary Heart Disease Sustained Release Tablet 30 mg," which contains Nifedipine.
I have been taking 30 mg of Nifedipine once daily every morning for over six months (for detailed information, please refer to http://www.nhi.gov.tw/Query/query1_list.aspx).
During a prior visit to an obstetrics and gynecology clinic, I showed the medication to the doctor, who said it was okay for me to continue taking it.
However, after researching online today, I found that pregnant women should not take this medication, and I am now very worried that I may have harmed my baby.
Please provide me with relevant information.
Thank you! (An anxious and troubled first-time mom)

Xinshou Mama, 30~39 year old female. Ask Date: 2016/01/29

Dr. Cao Guotao reply Obstetrics and Gynecology


Hello, you should continue taking your medication to control your high blood pressure.
Wishing you good health.

Reply Date: 2016/01/29

More Info


Managing hypertension during pregnancy is a critical concern for both maternal and fetal health. It is essential to understand the implications of medication use, particularly for those with pre-existing conditions like chronic hypertension.
Hypertension during pregnancy can manifest as gestational hypertension or preeclampsia, which can lead to serious complications if not managed properly. The causes of elevated blood pressure during pregnancy can include abnormal placental development, maternal immune responses, hormonal imbalances, and pre-existing conditions such as chronic hypertension or kidney disease. In your case, since you have a history of chronic hypertension, it is crucial to monitor your blood pressure closely and manage it effectively throughout your pregnancy.

Regarding the use of Nifedipine, which is a calcium channel blocker commonly prescribed for hypertension, it is classified as a Category C medication by the FDA. This means that while animal studies have shown adverse effects on the fetus, there are no adequate and well-controlled studies in pregnant women. However, Nifedipine is often used in pregnancy when the benefits outweigh the risks, particularly when managing severe hypertension. It is essential to follow your healthcare provider's recommendations, as they will weigh the risks and benefits based on your specific situation.

If your obstetrician has reviewed your medication and deemed it safe for you to continue, it is likely because they believe that the control of your blood pressure is paramount for both your health and that of your baby. Uncontrolled hypertension can lead to complications such as placental abruption, fetal growth restriction, and even stillbirth. Therefore, maintaining a stable blood pressure is crucial.

To address your concerns about potential harm to your baby, it is important to remember that many women with chronic hypertension have healthy pregnancies and deliver healthy babies with appropriate management. If you are feeling anxious about your medication, consider discussing your concerns with your healthcare provider. They can provide you with the most accurate information and may suggest alternative medications that are safer during pregnancy if necessary.

In addition to medication management, lifestyle modifications can also play a significant role in controlling hypertension during pregnancy. These include:
1. Dietary Changes: A diet rich in fruits, vegetables, whole grains, and lean proteins can help manage blood pressure. Reducing sodium intake is also crucial.

2. Regular Monitoring: Keep track of your blood pressure at home and report any significant changes to your healthcare provider.

3. Stress Management: Techniques such as prenatal yoga, meditation, or deep-breathing exercises can help reduce stress, which may contribute to elevated blood pressure.

4. Regular Prenatal Care: Attend all scheduled prenatal appointments to monitor your health and the development of your baby.

5. Physical Activity: Engage in moderate exercise as recommended by your healthcare provider, as it can help lower blood pressure and improve overall health.

In conclusion, while it is natural to feel anxious about medication use during pregnancy, it is essential to trust your healthcare provider's guidance. They are equipped to help you navigate these concerns and ensure the best possible outcome for you and your baby. If you have any further questions or concerns, do not hesitate to reach out to your healthcare provider for personalized advice and reassurance.

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