Can CT Scans Determine Lung Cancer Spread to the Pleura? - Pulmonology

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Can a CT scan determine if lung cancer has metastasized to the pleura?


Hello Doctor:
1.
Can a CT scan determine if lung cancer has invaded or metastasized to the visceral pleura or chest wall?
2.
In my mother's pre-operative examination report, it states "GGO (size 27mm) with slightly denser part solid center 'touching' medial apical pleura: differential diagnosis inflammatory or early lung cancer in view of adjacent inflammatory scars." Does the term "touching" indicate that the tumor has invaded or metastasized to the pleura, or does it simply describe the tumor's location? Thank you!

Awei, 30~39 year old female. Ask Date: 2016/01/30

Dr. Jian Shuntian reply Pulmonology


Hello: It is currently unclear whether it is a tumor, as the CT scan has not provided confirmation.
Although it is in contact with the pleura, this does not necessarily indicate pleural metastasis.
It is recommended to seek the opinion of a thoracic surgeon regarding the possibility of performing a thoracoscopy and resection surgery.
Sincerely, Jian Shun-Tian.

Reply Date: 2016/01/30

More Info


CT scans are a crucial tool in the evaluation and management of lung cancer, particularly in assessing whether the cancer has spread to the pleura or chest wall. To address your questions:
1. Can CT scans determine if lung cancer has invaded or metastasized to the visceral pleura or chest wall?
CT scans are quite effective in identifying changes in the lung and surrounding structures, including the pleura and chest wall. When lung cancer spreads, it can invade nearby structures, including the pleura, which is the membrane surrounding the lungs. Radiologists look for specific signs on CT scans that may indicate invasion, such as irregularities in the pleural surface, thickening of the pleura, or the presence of pleural effusion (fluid in the pleural space). However, while CT scans can suggest invasion, they cannot definitively confirm it. A biopsy or further imaging studies, such as PET scans, may be necessary for a conclusive diagnosis.

2. Regarding the report mentioning "GGO (size 27mm) with slightly denser part solid center 'touching' medial apical pleura":
The term "touching" in this context typically refers to the proximity of the ground-glass opacity (GGO) to the pleura, rather than indicating that the tumor has invaded the pleura. It suggests that the GGO is located near the pleural surface, which may raise concerns about potential invasion, especially if there are accompanying signs of malignancy or if the lesion has characteristics suggestive of lung cancer. However, without additional imaging or histological confirmation, it is not possible to definitively conclude that the tumor has invaded the pleura based solely on the CT findings.

In clinical practice, the interpretation of CT findings must be correlated with the patient's clinical history, physical examination, and other diagnostic tests. If there is a suspicion of pleural invasion or metastasis, further evaluation may be warranted, including a biopsy of the lesion or pleural fluid analysis if there is an effusion.

In summary, while CT scans are valuable in assessing lung cancer and its potential spread, they have limitations in definitively determining invasion into the pleura or chest wall. The interpretation of findings such as "touching" should be approached with caution, and further investigation may be necessary to clarify the nature of the lesion and its relationship to the pleura. If there are concerns about the possibility of malignancy, discussing these findings with your healthcare provider is essential for determining the appropriate next steps in management and follow-up.

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