Nodules on the Scrotum: Scabies or Other Causes? - Dermatology

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There are nodules on the skin?


I went to see a dermatologist because I had several nodules on my scrotum that were itchy.
The doctor took a quick look and immediately said it was a scabies infection.
I would like to know if nodules on the scrotum are definitely a sign of scabies, or could they also be caused by a sexually transmitted infection or other reasons?

Niming, 20~29 year old female. Ask Date: 2016/02/02

Dr. Li Yufen reply Dermatology


Hello: The presence of nodules on the scrotum may be due to scabies infection, but it could also simply be a common rash, scrotal calcification, or scrotal tumors.
If there are doubts about the diagnosis, you may seek a second opinion from another dermatologist nearby.
For information regarding scabies, you can refer to the article on the Dermatology Expert Health Network at http://www.drskincare.com.tw/Qa/Index.aspx?CID=15.
Thank you!

Reply Date: 2016/02/02

More Info


When it comes to nodules on the scrotum, it is essential to consider a range of potential causes, as not all nodules are indicative of scabies or any single condition. While your dermatologist has suggested scabies, which is a skin infestation caused by the Sarcoptes scabiei mite, there are several other possibilities that could explain the presence of nodules and itching in the scrotal area.

1. Scabies: As mentioned, scabies is characterized by intense itching, especially at night, and the appearance of small red bumps or nodules. These nodules can occur anywhere on the body, including the scrotum. Scabies is highly contagious and can be transmitted through direct skin-to-skin contact, making it a common concern in close-contact settings.

2. Folliculitis: This condition involves inflammation of the hair follicles, which can lead to the formation of small, red, pus-filled bumps or nodules. Folliculitis can be caused by bacterial infections, irritation from shaving, or friction from clothing.

3. Cysts: Sebaceous cysts or epidermoid cysts can develop in the scrotal area. These are typically benign and can appear as small, firm nodules. They may or may not be associated with discomfort or itching.

4. Sexually Transmitted Infections (STIs): Certain STIs, such as genital herpes or molluscum contagiosum, can cause nodules or lesions on the scrotum. Genital herpes may present with painful blisters, while molluscum contagiosum typically appears as small, firm, painless bumps.

5. Lichen Simplex Chronicus: This is a skin condition resulting from chronic scratching or irritation, leading to thickened, itchy patches of skin. It can occur in the genital area and may present with nodular formations.

6. Other Dermatoses: Conditions such as psoriasis or eczema can also affect the scrotum, leading to the development of nodules or plaques that may be itchy.

Given the variety of potential causes, it is crucial to have a thorough evaluation by a healthcare professional. While your dermatologist has made an initial diagnosis, further investigation may be warranted, especially if the symptoms persist or worsen. A skin scraping or biopsy may be performed to confirm the diagnosis of scabies or to rule out other conditions.

In summary, while scabies is a possibility, it is not the only explanation for nodules on the scrotum. Other conditions, including folliculitis, cysts, STIs, and various skin disorders, should also be considered. If you have concerns about your diagnosis or if your symptoms do not improve with treatment, seeking a second opinion or further evaluation from a specialist in dermatology or urology may be beneficial. It is essential to address any underlying issues promptly to prevent complications and ensure appropriate treatment.

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