Central Serous Retinopathy: Causes and Recurrence Explained - Ophthalmology

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Central serous retinopathy


Doctor: I went to see an ophthalmologist who examined my fundus without dilation.
They said the water patterns are caused by retinal edema.
However, why do both eyes have this issue, seemingly in the same location in the upper right quadrant? It lasted for about 20 minutes.
The examination revealed mild leakage in both eyes, but this time I didn't experience any shadows in my vision.
Why is this happening? My vision was previously quite good, so why does it keep recurring? Thank you, doctor.

Gao Xiansheng, 40~49 year old female. Ask Date: 2016/02/24

Dr. Gao Pilin reply Ophthalmology


Hello Mr.
Gao,
You previously asked the following: "Hello doctor, six months ago I experienced leakage in my macula, and black spots appeared in my vision.
A month later, it recovered, but not long after, it recurred.
After a while, it improved again, but the third episode occurred.
I underwent a fluorescein angiography, which confirmed leakage.
Recently, my vision improved to 0.9.
I suspect that the three episodes of leakage were related to back scrubbing or cupping therapy.
Could this affect my eyes? Yesterday, I noticed transparent water-like patterns in the upper right area of both eyes; they appeared the same in both eyes and disappeared after twenty minutes.
Today, it recurred, affecting the upper right area of both eyes again.
What could be the cause, doctor? Is it related to the optic nerve or the retina? I do not have myopia or diabetes, and my blood pressure is around 135/95.
I am concerned and troubled about this.
Six months ago, I had a normal brain CT scan because I was experiencing severe pain in the back of my head all day.
According to the source: http://www.kmuh.org.tw/www/kmcj/data/10105/14.htm, the exact cause of the condition remains unclear, but it may be related to psychological stress in patients.
It commonly occurs in healthy males aged 25 to 55.
Patients may suddenly notice a dark spot in the center of their vision, with images appearing darker, smaller, or even distorted, and a decrease in color sensitivity.
Typically, vision does not drop below 0.6, and fortunately, most cases occur in one eye.
Research indicates that patients tend to have Type A personality traits, characterized by strong ambition, proactivity, impatience, and high self-expectations.
Additionally, the use of steroids or conditions like Cushing's syndrome may increase the risk of this disease.
Common triggering factors include lack of sleep, insomnia, stress, fatigue, and emotional fluctuations.
This condition primarily affects the central part of the retina, known as the macula, where many photoreceptor cells are concentrated, significantly impacting vision and color perception.
Once affected, the macula may exhibit edema.
Currently, there are no specific pharmacological treatments.
Approximately 80-90% of patients will have their macular edema resolve on its own within three to four months, accompanied by gradual vision recovery; however, a small percentage may experience permanent vision loss, and about 40-50% may have recurrences.
Taiwan E-Hospital Puzi Hospital Ophthalmology: Monday to Friday, 8:00 AM to 12:00 PM; Wednesday afternoon, 1:00 PM to 4:30 PM.
Online responses are for reference only; it is necessary to seek medical attention at a healthcare facility.
I hope to have the opportunity to assist you.

Best regards,
Gao Pilin

Reply Date: 2016/02/24

More Info


Central Serous Retinopathy (CSR) is a condition characterized by the accumulation of fluid under the retina, leading to visual disturbances. It primarily affects young to middle-aged adults and is more common in males. The exact cause of CSR is not fully understood, but several factors have been identified that may contribute to its development and recurrence.


Causes of Central Serous Retinopathy
1. Stress: Psychological stress is one of the most commonly cited triggers for CSR. Stress can lead to the release of corticosteroids, which may increase vascular permeability in the choroid, resulting in fluid leakage under the retina.

2. Hormonal Factors: Fluctuations in hormones, particularly cortisol, have been associated with CSR. Some studies suggest that elevated cortisol levels can lead to changes in the retinal pigment epithelium, contributing to fluid accumulation.

3. Lifestyle Factors: Certain lifestyle choices, such as smoking and excessive caffeine consumption, have been linked to an increased risk of CSR. These factors may affect blood flow and vascular health, exacerbating the condition.

4. Medical Conditions: Conditions such as hypertension, sleep apnea, and autoimmune diseases can predispose individuals to CSR. These conditions may affect the body's ability to regulate fluid balance and vascular integrity.

5. Genetic Predisposition: Some individuals may have a genetic susceptibility to CSR, making them more prone to developing the condition.


Recurrence of Central Serous Retinopathy
CSR can be a recurrent condition, and several factors may contribute to its recurrence:
1. Persistent Stress: If the underlying stressors that triggered the initial episode are not addressed, the likelihood of recurrence increases. Managing stress through lifestyle changes, therapy, or relaxation techniques can be beneficial.

2. Ongoing Hormonal Imbalances: Hormonal fluctuations, particularly related to stress and adrenal function, can lead to repeated episodes of CSR. Monitoring and managing these hormonal levels may help reduce recurrence.

3. Lifestyle Choices: Continued smoking, high caffeine intake, and poor sleep hygiene can contribute to the recurrence of CSR. Making healthier lifestyle choices can significantly impact the frequency of episodes.

4. Underlying Health Conditions: If there are unmanaged health issues, such as hypertension or sleep apnea, these may need to be addressed to prevent further episodes of CSR.


Conclusion
In your case, the bilateral occurrence of CSR, particularly in the same area of the retina, suggests a systemic issue rather than localized damage. The absence of significant visual impairment, such as black spots, is a positive sign, but it is essential to monitor the condition closely. Regular follow-ups with your ophthalmologist are crucial for managing CSR and preventing complications.
If you experience recurrent episodes, consider discussing stress management techniques, lifestyle modifications, and potential underlying health issues with your healthcare provider. They may also recommend imaging studies or other diagnostic tests to monitor the condition and assess for any changes in the retina.
In summary, while CSR can be distressing and recurrent, understanding its causes and taking proactive steps can help manage the condition effectively.

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