Chronic Intermittent Cough: Causes and Treatment Options - Pulmonology

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Chronic intermittent cough?


Hello, Dr.
Zhou.
I have been experiencing intermittent coughing for a year.
I always feel like I can't clear my left lung, and my left throat is itchy.
Whenever it itches, I feel the urge to cough.
Occasionally, I have some clear phlegm, which is slightly more at night.
I had a CT scan done, which did not show any significant abnormalities.
The report mentioned a 3.5 mm irregular density nodule that could be fibrosis, as well as a 2 mm non-calcified nodule and another similar nodule, located in the left and right lungs respectively.
They might be old granulomas.
I have been seeing doctors in Australia for a year, but the cough has not stopped.
I have tried various cough medications, both traditional and Western, with no effect.
I would like to ask you what the problem might be and if there are any effective treatment options.
Thank you.

Sherry, 50~59 year old female. Ask Date: 2016/02/24

Dr. Zhou Ziguang reply Pulmonology


Hello: 1.
There are many causes of chronic cough.
In addition to issues related to the lungs and bronchitis, it may also be due to post-nasal drip, gastroesophageal reflux disease (GERD), asthma, and other possibilities that require further differential diagnosis.
2.
For the pulmonary nodule described, a lung biopsy can be performed.
If a surgical biopsy is not conducted, a follow-up chest CT scan should be done in approximately six months.

Reply Date: 2016/02/24

More Info


Chronic intermittent cough can be a frustrating and debilitating condition, especially when it persists for an extended period, as you have experienced. Based on your description, it seems that you have been dealing with this cough for about a year, with associated symptoms such as a persistent itch in the left throat and occasional clear sputum, particularly at night. The CT scan results indicating small nodules and possible fibrosis may add complexity to your situation, but they do not provide a definitive diagnosis on their own.


Possible Causes of Chronic Intermittent Cough
1. Post-Nasal Drip: One of the most common causes of chronic cough is post-nasal drip, where mucus from the nasal passages drips down the back of the throat, leading to irritation and a cough reflex. This can be exacerbated by allergies or sinusitis.

2. Asthma: Given your symptoms of throat itchiness and cough, asthma could be a potential cause. Asthma can present with a chronic cough, especially at night or early morning, and may be associated with wheezing or shortness of breath.

3. Gastroesophageal Reflux Disease (GERD): GERD can cause a chronic cough due to acid irritating the throat and airways. This is often worse at night when lying down.

4. Chronic Bronchitis: If you have a history of smoking or exposure to irritants, chronic bronchitis could be a consideration. This condition is characterized by a productive cough and can persist for months.

5. Interstitial Lung Disease: The findings of fibrosis on your CT scan could suggest an underlying interstitial lung disease, which can present with a chronic cough and may require further evaluation.

6. Infections: Although less likely given the duration, chronic infections such as tuberculosis or atypical pneumonia could also cause a persistent cough.


Treatment Options
1. Identify and Treat Underlying Causes: The first step in managing your cough is to identify any underlying causes. This may involve further testing, such as pulmonary function tests to assess for asthma or additional imaging studies.

2. Medications:
- Antihistamines: If allergies are suspected, antihistamines may help reduce post-nasal drip.

- Inhaled Corticosteroids: If asthma is diagnosed, inhaled corticosteroids can help reduce inflammation in the airways.

- Proton Pump Inhibitors (PPIs): If GERD is suspected, PPIs can help reduce acid production and alleviate symptoms.

- Cough Suppressants: While these may provide temporary relief, they should not be the primary treatment unless the cough is severely disruptive.

3. Lifestyle Modifications:
- Avoid Irritants: Stay away from smoke, strong odors, and other environmental irritants.

- Stay Hydrated: Drinking plenty of fluids can help thin mucus and reduce throat irritation.

- Elevate the Head While Sleeping: If GERD is a concern, elevating the head while sleeping can help prevent acid reflux.

4. Follow-Up Care: Given the complexity of your symptoms and the CT findings, regular follow-up with a healthcare provider is essential. This may include seeing a pulmonologist for specialized care.

5. Consider a Second Opinion: If you feel that your current treatment plan is not effective, seeking a second opinion from another healthcare provider may provide new insights or treatment options.


Conclusion
Chronic cough can stem from various causes, and effective treatment often requires a comprehensive approach that addresses the underlying issues. Given your symptoms and the CT findings, it is crucial to continue working closely with your healthcare provider to explore all potential causes and treatment options. If your cough persists or worsens, further evaluation and possibly more aggressive treatment may be necessary. Remember, managing chronic cough often requires patience and persistence, as finding the right diagnosis and treatment can take time.

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