Vaccination Schedule for Newborns: Delayed First Dose Concerns - Pediatrics

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Newborn Vaccines


Hello Doctor, my baby is scheduled to receive the first dose of the 13-valent pneumococcal conjugate vaccine and the pentavalent vaccine on February 24, 2016.
However, our whole family is abroad and we plan to return to Taiwan in early April.
By then, my baby will be almost 4 months old.
Is it acceptable to administer the first dose of the vaccine at that age? If so, when can the second dose be given? Thank you.

NICO, 30~39 year old female. Ask Date: 2016/02/25

Dr. Xiao Kaiwen reply Pediatrics


It is acceptable to delay vaccination; however, one must bear the risk of infection before receiving the vaccine.
The interval between the first and second doses of the pentavalent vaccine is at least four weeks, while the interval between the first and second doses of the 13-valent pneumococcal vaccine is at least eight weeks.

Reply Date: 2016/02/25

More Info


When it comes to vaccination schedules for newborns, it is important to adhere to the recommended timelines to ensure optimal protection against various diseases. However, life circumstances, such as traveling abroad, can sometimes lead to delays in vaccination. In your case, your baby was scheduled to receive the first doses of the 13-valent pneumococcal conjugate vaccine (PCV13) and the pentavalent vaccine (5-in-1) on February 24, 2016, but due to being abroad, the vaccinations will be delayed until early April when your baby is nearly four months old.

First and foremost, it is generally acceptable to delay vaccinations. The Centers for Disease Control and Prevention (CDC) and other health organizations recognize that while it is best to follow the recommended schedule, vaccinations can be administered later without significant risk to the child’s health. However, it is crucial to understand that delaying vaccinations does leave your baby vulnerable to infections during that time.
For the specific vaccines in question, the 5-in-1 vaccine typically includes protection against diphtheria, tetanus, pertussis (whooping cough), polio, and Haemophilus influenzae type b (Hib). The recommended schedule for the 5-in-1 vaccine is as follows:
- First dose: 2 months
- Second dose: 4 months
- Third dose: 6 months
- Fourth dose: 15-18 months
- Fifth dose: 4-6 years
For the PCV13, the schedule is:
- First dose: 2 months
- Second dose: 4 months
- Third dose: 6 months
- Fourth dose: 12-15 months
Given that your baby will be almost 4 months old when you return, you can administer the first doses of both vaccines upon your return. It is advisable to consult with your pediatrician to determine the best time to catch up on these vaccinations.
In terms of the timing for the second doses, the CDC recommends that the second dose of the 5-in-1 vaccine should be given at least four weeks after the first dose, and the second dose of the PCV13 should be given at least eight weeks after the first dose. Therefore, if you administer the first doses shortly after returning, you can schedule the second doses as follows:
- For the 5-in-1 vaccine, the second dose can be given at around 4 months after the first dose.

- For the PCV13, the second dose can be given at around 6 months after the first dose.

It is essential to keep a record of the vaccinations and follow up with your healthcare provider to ensure that your baby receives all necessary vaccinations in a timely manner. Additionally, if your baby experiences any adverse reactions after receiving the vaccines, such as high fever or unusual behavior, it is important to seek medical attention promptly.

In conclusion, while it is best to adhere to the vaccination schedule, delays can be managed effectively with the guidance of a healthcare professional. Your baby's health and safety are paramount, and staying informed about vaccination schedules and potential risks will help ensure that your child is protected against preventable diseases.

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