Should Cerebral Aneurysms Be Actively Treated? A Neurological Perspective - Neurosurgery

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Should cerebral venous aneurysms be actively managed?


I fainted on January 8, 2016, and after an MRI examination, a neurologist assessed that I have a vascular malformation (approximately 1.4 cm, located in the right frontal lobe, about 2.5 cm from the intracranial space) and recommended regular follow-up.
However, a neurosurgeon believes that since a vascular malformation has been identified and it is not located near critical neural structures, it should be actively addressed while I am still young.
Recently, a cardiologist determined through a tilt table test that my fainting was caused by vasovagal syncope and is unrelated to the cerebral vascular malformation.
I am currently taking prophylactic anticonvulsant medication (name: Levetiracetam), one tablet in the morning and one in the evening.
I would like to ask the physician whether it is advisable to pursue active treatment for the vascular malformation.
Thank you.

Eugene, 40~49 year old female. Ask Date: 2016/02/25

Dr. Zhang Junwei reply Neurosurgery


This question is difficult to answer online; please consult further during your outpatient visit!

Reply Date: 2016/02/25

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The question of whether cerebral aneurysms should be actively treated is a complex one that depends on various factors, including the size and location of the aneurysm, the patient's age and overall health, and the presence of symptoms. In your case, you have a 1.4 cm aneurysm located in the right frontal lobe, which is approximately 2.5 cm from the intracranial space. The differing opinions between your neurologist and neurosurgeon highlight the nuances involved in managing cerebral aneurysms.

Cerebral aneurysms are abnormal bulges in the walls of blood vessels in the brain. They can be classified as either symptomatic or asymptomatic. Symptomatic aneurysms may cause headaches, neurological deficits, or even rupture, leading to subarachnoid hemorrhage, which is a medical emergency. Asymptomatic aneurysms, on the other hand, do not present any immediate symptoms and are often discovered incidentally during imaging studies.

In general, the management of cerebral aneurysms can be categorized into observation and intervention. Observation is typically recommended for small, asymptomatic aneurysms, especially those less than 7 mm in size. In your case, a 1.4 cm aneurysm is larger than this threshold, which raises the question of whether intervention is warranted. The fact that your aneurysm is not located near critical neurological structures may also influence the decision to treat.

The neurosurgeon's recommendation for active treatment may be based on the potential risks associated with the aneurysm, including the possibility of future rupture. While the risk of rupture increases with the size of the aneurysm, it is also influenced by other factors such as the patient's family history of aneurysms, hypertension, and other vascular risk factors. Given your young age, the neurosurgeon may feel that the benefits of treating the aneurysm now outweigh the risks of waiting.

On the other hand, the neurologist's recommendation for regular monitoring suggests a more conservative approach, which is often appropriate for patients who are asymptomatic and have a lower risk profile. Regular follow-up with imaging studies can help monitor the aneurysm for any changes in size or characteristics.

Regarding your recent syncope (fainting), it is important to note that while the cardiac evaluation indicated that it was likely due to vasovagal syncope, it is essential to continue monitoring your neurological status. The use of antiepileptic medication (like the one you mentioned) may be a precautionary measure, especially if there is any concern about seizure activity related to the aneurysm.

In conclusion, the decision to actively treat a cerebral aneurysm should be made collaboratively between you and your healthcare team, considering all the relevant factors. It is advisable to have a thorough discussion with both your neurologist and neurosurgeon to weigh the risks and benefits of intervention versus observation. If you have any further questions or concerns, seeking a second opinion from another neurosurgeon or a specialized center may also provide additional insights into your specific case. Ultimately, the goal is to ensure your safety and well-being while minimizing unnecessary interventions.

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