Unilateral Breast Enlargement and Pain: Causes and Concerns - Breast and Thyroid

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Unilateral breast enlargement with a lump and tenderness under the areola, along with erythema?


The left breast is swollen, with a lump and tenderness beneath the areola.
The following day, the breast feels enlarged again, accompanied by the same tenderness and lump.
During a shower in the evening, redness around the areola was noticed.

Niming, 10~19 year old female. Ask Date: 2016/03/03

Dr. Zhou Jiazhen reply Breast and Thyroid


Dear Anonymous: This is often caused by changes in internal endocrine function, and sometimes diet (such as fried foods, high fat, caffeine, etc.) can also play a role.
Emotional stress can also contribute at times, but if there are symptoms, it is advisable to seek a consultation for examination.

Reply Date: 2016/03/03

More Info


Unilateral breast enlargement and pain can be concerning for many individuals, especially when accompanied by symptoms such as tenderness, lumps, and redness. Understanding the potential causes and implications of these symptoms is crucial for proper management and peace of mind.

Firstly, unilateral breast enlargement can occur due to several benign conditions. One common cause is hormonal fluctuations, particularly in women of reproductive age. The menstrual cycle can lead to changes in breast tissue, causing swelling and tenderness. This is often due to the influence of estrogen and progesterone, which can lead to fluid retention and changes in breast tissue density.
Another potential cause is the presence of a benign breast condition such as a fibroadenoma or a cyst. Fibroadenomas are solid, non-cancerous lumps that can develop in the breast tissue and may cause localized swelling and tenderness. Cysts, which are fluid-filled sacs, can also lead to similar symptoms. These conditions are generally not serious but can cause discomfort and anxiety.

In your case, the presence of a lump beneath the areola and the associated tenderness raises the possibility of a condition known as periductal mastitis, which is an inflammation of the ducts beneath the nipple. This condition can cause localized pain, swelling, and sometimes redness, particularly if there is an infection involved. It is more common in women who are breastfeeding but can occur in non-lactating women as well.

Another important consideration is the possibility of an infection, such as mastitis, which can occur even in non-lactating women. Symptoms of mastitis include localized pain, swelling, redness, and sometimes fever. If an infection is suspected, it is crucial to seek medical attention promptly, as antibiotics may be necessary.

While breast cancer is a concern that often comes to mind with any new breast symptoms, it is important to note that unilateral breast pain and enlargement are not common indicators of breast cancer. Breast cancer typically presents with a hard, immovable lump rather than a painful swelling. However, any new or unusual changes in the breast should be evaluated by a healthcare professional to rule out malignancy.

Given your symptoms of unilateral enlargement, tenderness, and redness, it is advisable to consult a healthcare provider, preferably a breast specialist. They may recommend imaging studies such as a mammogram or ultrasound to assess the breast tissue further and determine the nature of the lump. A physical examination will also help in identifying any signs of infection or other underlying conditions.

In summary, unilateral breast enlargement and pain can arise from various benign conditions, including hormonal changes, cysts, fibroadenomas, or infections. While these conditions are often not serious, it is essential to seek medical evaluation to ensure proper diagnosis and treatment. Early intervention can alleviate symptoms and address any underlying issues, providing reassurance and peace of mind.

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