Cervical Cancer Vaccine: Risks and Sexual Activity Explained - Obstetrics and Gynecology

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I would like to inquire about the cervical cancer vaccine?


Hello, doctor.
I have a question I would like to ask you.
I heard that it is best to receive the cervical cancer vaccine before engaging in sexual intercourse.
If I have a single sexual partner, is there still a risk of developing cervical cancer? I want to know if oral sex is considered a form of sexual activity.
I'm really scared! I originally planned to get the vaccine before engaging in any sexual activity, but I couldn't resist and went ahead with oral sex.
What should I do? Will my vaccination effectiveness be lower compared to someone who has not engaged in any sexual activity or oral sex? Thank you!

Lily, 20~29 year old female. Ask Date: 2016/03/08

Dr. Zhang Kunmin reply Obstetrics and Gynecology


Hello, regarding important information about the HPV vaccine, please note the following:
1.
HPV types 16 and 18 are the most common high-risk human papillomaviruses, responsible for over 70% of cervical cancer cases.
HPV types 6 and 11 are the most common low-risk human papillomaviruses, causing 90% of genital warts (condyloma acuminatum).

2.
The quadrivalent HPV vaccine is intended for prevention, not treatment.

3.
The expected effects of the quadrivalent HPV vaccine include a 65% to 70% reduction in the risk of developing cervical cancer, a 50% reduction in cervical precancerous lesions, a 90% reduction in genital warts, and a 97% reduction in HPV types 16 and 18 infections.

4.
Receiving the quadrivalent HPV vaccine does not replace routine cervical cancer screening.
Women who have received the quadrivalent HPV vaccine should still undergo regular Pap smear tests.
All women who have ever been sexually active must follow clinical guidelines for Pap smears and have them performed regularly.
If a woman has not had a Pap smear in the past year, it is recommended that she undergo one.

5.
Women who are currently diagnosed with cervical cancer or precancerous conditions are not advised to receive the quadrivalent HPV vaccine.

6.
If you are already infected with certain types of human papillomavirus, receiving the quadrivalent HPV vaccine will not prevent diseases caused by those already infected types.

7.
The quadrivalent HPV vaccine is classified as pregnancy category B.
If you become pregnant while receiving the quadrivalent HPV vaccine, there is no need to terminate the pregnancy.
It is safe to receive the quadrivalent HPV vaccine while breastfeeding.
Like other vaccines, the cervical cancer vaccine is more effective and valuable when administered early, but it will not be ineffective if sexual activity has occurred.
For more detailed information, please refer to the explanations provided by the Obstetrics and Gynecology Society: http://www1.cgmh.org.tw/intr/intr5/c6700/hpv%20web/VaccineNote.html.
Thank you! Wishing you peace and health, Dr.
Zhang.

Reply Date: 2016/03/08

More Info


The concerns surrounding the HPV (Human Papillomavirus) vaccine and its relationship with sexual activity, including oral sex, are quite common. Let's break down the key points regarding the HPV vaccine, its efficacy, and the risks associated with sexual behavior before and after vaccination.

Firstly, it is important to understand that the HPV vaccine is designed to protect against certain strains of the virus that are known to cause cervical cancer and genital warts. The most common high-risk types associated with cervical cancer are HPV types 16 and 18, which account for over 70% of cervical cancer cases. The vaccine is most effective when administered before the onset of sexual activity, as it provides the best chance of preventing infection from these high-risk HPV types.

Now, regarding your question about oral sex: yes, oral sex is considered a form of sexual activity. HPV can be transmitted through any skin-to-skin contact in the genital area, including oral sex. Therefore, engaging in oral sex does carry some risk of HPV transmission, especially if one of the partners is infected with a strain of HPV that can lead to cancer or warts.

If you have already engaged in oral sex before receiving the vaccine, it is understandable to feel anxious about the potential impact on the vaccine's efficacy. However, it is crucial to note that the HPV vaccine does not lose its effectiveness simply because a person has had sexual contact. The vaccine is designed to prevent infection from the types of HPV it covers, but if you have already been exposed to a specific type of HPV prior to vaccination, the vaccine will not protect against that type. This means that if you have been exposed to HPV types covered by the vaccine, you may not receive protection against those specific types, but you will still benefit from protection against other types that you have not been exposed to.

Regarding the timing of the vaccine's protective effects, it is generally recommended to complete the full vaccination series (usually three doses) for optimal protection. The vaccine starts to provide some level of immunity after the first dose, but full protection is typically achieved after the completion of all doses. Therefore, if you received your second dose in July and are scheduled to receive your third dose in November, you can expect to have full protection by the end of December, assuming you complete the series as planned.

In summary, while engaging in oral sex does pose some risk of HPV transmission, it does not negate the effectiveness of the HPV vaccine. The vaccine is still beneficial, especially in providing protection against other HPV types. It is important to continue regular cervical cancer screenings, such as Pap smears, even after vaccination, as these screenings are crucial for early detection of any abnormalities. Additionally, practicing safe sex, such as using condoms, can further reduce the risk of HPV transmission and other sexually transmitted infections.

If you have further concerns or questions about your specific situation, it is advisable to consult with a healthcare provider who can provide personalized guidance based on your health history and circumstances.

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