Persistent Itchy Red Spots After Steroid Treatment: Causes and Solutions - Dermatology

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Repeatedly appearing red spots in different locations on the body that are very itchy?


Due to a severe asthma attack that required hospitalization, I was discharged and treated with a large amount of steroids (starting with 12 pills a day and gradually reducing during follow-up visits) and other medications (oral medications for about two months).
During the treatment period, I experienced many side effects listed on the medications (tremors, confusion, headaches, etc.), and my sleep was very poor, averaging only 4 to 5 hours a night for nearly two months.
Currently, the side effects and sleep have returned to normal.
I am no longer taking steroids but am still using maintenance medications for my airways.

When the steroid dosage was reduced to one pill a day, I began to develop itchy red spots in various locations on my body (hands, abdomen, neck, ears, armpits, face), which have been recurring.
I have seen a dermatologist, who prescribed ointments and oral medications, but each time I visit, the doctor suggests changing the medications and ointments, and the issue has persisted for several weeks, which is quite bothersome.

As for my home environment, it is regularly cleaned, my diet is light, and my sleep schedule is consistent.
I asked my asthma doctor if the medications I am taking could be related to this issue, but the doctor said it was not a concern.
I would like to consult Dr.
Lee on how I should treat this condition or what I need to pay attention to.
Is this related to the medications I previously used? Could it be connected to a decrease in my immune system? Since I have been taking Western medicine, would it be better to consider traditional Chinese medicine for treatment?

Beiti, 30~39 year old female. Ask Date: 2016/03/09

Dr. Li Yufen reply Dermatology


Hello: It is not possible to determine the specific skin condition causing the recurrent red spots based solely on the description.
If it is a drug allergy, it is usually related to medications taken within the past month.
Given the history of severe asthma and allergic constitution, it is recommended to conduct allergy testing and allergen screening to identify potential causes.
Thank you!

Reply Date: 2016/03/09

More Info


Persistent itchy red spots after steroid treatment can be quite distressing, especially following a significant medical event like a severe asthma attack that required hospitalization and high doses of corticosteroids. The symptoms you describe—itchy red spots appearing on various parts of your body—can be attributed to several factors, including the effects of steroid treatment, potential allergic reactions, or even underlying skin conditions that may have been exacerbated by the steroids.

Corticosteroids are powerful anti-inflammatory medications that can suppress the immune system. While they are effective in managing conditions like asthma, they can also lead to side effects, including skin changes. Prolonged use of steroids can cause thinning of the skin, making it more susceptible to irritations and infections. Additionally, as your body adjusts to the reduction of steroids, you may experience rebound effects, where the skin reacts to the sudden change in medication.

The persistent itchy red spots you are experiencing could also indicate a condition known as steroid withdrawal dermatitis. This occurs when the body reacts to the cessation of steroids, leading to inflammation and irritation of the skin. It’s essential to differentiate this from other potential causes, such as allergic reactions to medications or topical agents, or even conditions like eczema or psoriasis, which may flare up due to stress or changes in medication.

Given that you've already consulted with a dermatologist and received various treatments without significant improvement, it may be beneficial to consider a few additional steps:
1. Patch Testing: If you suspect an allergic reaction, a dermatologist may recommend patch testing to identify any specific allergens that could be causing your symptoms.

2. Moisturization: Keeping the skin well-moisturized can help alleviate dryness and irritation. Look for fragrance-free, hypoallergenic moisturizers that can provide a protective barrier for your skin.

3. Avoid Irritants: Be mindful of potential irritants in your environment, including soaps, detergents, and skincare products. Opt for gentle, non-irritating formulations.

4. Diet and Lifestyle: While you mentioned maintaining a light diet and regular sleep, consider incorporating anti-inflammatory foods, such as omega-3 fatty acids (found in fish and flaxseeds), fruits, and vegetables, which may help support your skin health.

5. Consult a Specialist: If your symptoms persist, it may be worthwhile to seek a second opinion from another dermatologist or a specialist in allergic diseases. They may have different insights or treatment options that could be more effective.

6. Consider Traditional Medicine: If you are interested in exploring traditional Chinese medicine (TCM) or herbal remedies, consult with a qualified practitioner who can assess your condition holistically and provide tailored recommendations. However, ensure that any herbal treatments do not interact negatively with your current medications.

7. Monitor Your Symptoms: Keep a diary of your symptoms, noting any changes in your environment, diet, or medications. This information can be invaluable for your healthcare providers in determining the cause of your skin issues.

In conclusion, while it is unlikely that your current medications for asthma are directly causing the itchy red spots, the history of steroid use and the subsequent withdrawal may play a significant role in your skin condition. It is essential to work closely with your healthcare providers to find an effective treatment plan that addresses both your asthma and skin symptoms. Patience and persistence are key, as skin conditions can take time to resolve, especially after significant medical treatments.

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