and Treating Nail Edge Warts: Options and Concerns - Dermatology

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Nail edge warts


Hello Doctor, I have had a wart on the edge of the nail of my left middle finger for about 6 to 7 years.
In the past two years, I have been undergoing cryotherapy approximately every 10 days, but the wart has started to grow from the edge of the nail into the nail itself, becoming larger and causing my nail to deform and look unsightly.
I would like to understand why there has been no improvement despite ongoing treatment.
The long-term cryotherapy has made me feel physically and mentally exhausted, and my finger looks very unattractive.
Currently, in addition to cryotherapy, I am also applying salicylic acid.
Are there any other methods I can try to eliminate it? I want to do everything I can to get rid of it.
Additionally, a doctor has suggested electrosurgery, which would require removing one-third of the nail and excising the wart, potentially resolving the issue in one go.
However, the recovery would take a month, the nail may not grow back completely, and there is still a chance of recurrence.
Should I consider electrosurgery? I would greatly appreciate your advice!

Ray, 20~29 year old female. Ask Date: 2016/03/09

Dr. Wu Yuxin reply Dermatology


The aforementioned methods are the main treatments currently available.
Periungual warts are inherently difficult to treat, and some damage to the surrounding tissue during the treatment process is inevitable.
If cryotherapy combined with salicylic acid treatment does not seem effective, it may be worth considering the second physician's recommendation.

Reply Date: 2016/03/09

More Info


Nail edge warts, also known as periungual warts, can be particularly troublesome due to their location and the potential for them to cause nail deformity. These warts are caused by the human papillomavirus (HPV) and can be persistent and resistant to treatment, as you've experienced over the past six to seven years. It's understandable that the ongoing treatment and the appearance of your finger have led to feelings of frustration and fatigue.


Why Persistent Treatment May Not Be Effective
1. Virus Persistence: The HPV responsible for warts can be quite resilient. Even with treatments like cryotherapy (freezing), the virus may not be completely eradicated, allowing the wart to regrow or spread deeper into the nail bed.

2. Location: The periungual area is particularly challenging because the warts can invade the nail matrix, leading to nail deformities. This can make treatment more complicated, as the wart may not be fully accessible for removal.

3. Immune Response: Individual immune responses to HPV vary. Some people may have a robust immune response that can eventually clear the virus, while others may struggle to mount an effective response, leading to persistent warts.


Treatment Options
1. Cryotherapy: As you've been undergoing, this method involves freezing the wart with liquid nitrogen. While effective for many, it may require multiple sessions, and as you've noted, it may not be yielding the desired results.

2. Salicylic Acid: This topical treatment works by exfoliating the wart and surrounding skin. It can be effective, but it often requires consistent application over weeks or months.

3. Electrosurgery (Electrocautery): This method involves burning the wart with an electric current. While it can be effective in removing the wart, it does come with risks, such as scarring and the potential for nail deformity. The need to remove part of the nail and the recovery time are significant considerations.

4. Laser Treatment: Laser therapy can target the wart tissue specifically and may be an option if other treatments have failed. However, it can be costly and may require multiple sessions.

5. Immunotherapy: This approach aims to stimulate the immune system to fight off the virus. Treatments can include topical agents like imiquimod, which can help in some cases.

6. Surgical Excision: In cases where the wart is deeply embedded or has caused significant nail deformity, surgical removal may be necessary. This would involve cutting out the wart and possibly part of the nail matrix.


Considerations for Electrosurgery
- Recovery Time: As mentioned, electrosurgery requires careful post-operative care, and you may need to avoid certain activities while the area heals.

- Nail Growth: There is a possibility that the nail may not grow back perfectly, and there is a risk of recurrence.

- Consultation: It’s crucial to discuss the potential outcomes and risks with your dermatologist or a hand specialist. They can provide insights based on your specific case and help you weigh the benefits against the risks.


Psychological Impact
The psychological toll of dealing with a persistent wart, especially one that affects your appearance, should not be underestimated. It’s important to address these feelings with your healthcare provider, as they may be able to offer support or refer you to a mental health professional if needed.


Conclusion
Given your situation, it may be beneficial to consult with a dermatologist who specializes in nail disorders. They can provide a comprehensive evaluation and discuss the most appropriate treatment options tailored to your needs. If you decide to consider electrosurgery, ensure you have a thorough discussion about the procedure, recovery, and potential outcomes. Remember, persistence is key in treating warts, and exploring various treatment modalities may ultimately lead to a successful resolution.

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