Unusual Bumps on the Glans: Pearly Penile Papules or Something Else? - Urology

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When it comes to unusual bumps on the glans, particularly those that appear during an erection, it’s important to differentiate between normal anatomical variations and potential medical concerns. Based on your description, it sounds like you may be observing a condition known as pearly penile papules (PPP), which are small, benign bumps that typically appear around the corona of the glans. However, since you mentioned that these bumps are larger than typical PPP and seem to be more like fluid-filled blisters, it’s essential to consider other possibilities.

Pearly penile papules are common and harmless, often appearing as small, dome-shaped, white or skin-colored bumps. They are not associated with any disease and do not require treatment unless they cause psychological distress. They are a normal anatomical variant and are particularly common in uncircumcised men.
On the other hand, if the bumps you are experiencing are more pronounced, larger, and appear fluid-filled, they could potentially be a different condition. One possibility is a condition known as a sebaceous cyst, which can occur when sebaceous glands become blocked. These cysts are generally painless and can vary in size. They are also benign and typically do not require treatment unless they become infected or bothersome.

Another consideration could be a condition called molluscum contagiosum, which is a viral infection that can cause small, raised, flesh-colored or pearly bumps. These bumps can sometimes appear similar to PPP but may have a central dimple and can be itchy or irritating.

Given that you have not engaged in sexual activity for an extended period and have previously undergone comprehensive testing without any sexually transmitted infections (STIs), it is less likely that these bumps are related to an infectious process. However, it is still essential to monitor any changes in size, color, or sensation of the bumps.
If the bumps persist, change, or cause you concern, it is advisable to consult a healthcare professional, preferably a urologist or a dermatologist. They can perform a physical examination and, if necessary, conduct further tests to determine the exact nature of the bumps.
In conclusion, while pearly penile papules are a common and benign condition, the characteristics you describe suggest that it would be prudent to seek medical advice to rule out other potential issues. Regular self-examination and awareness of any changes in your body are important for maintaining sexual health. Remember, open communication with a healthcare provider can help alleviate concerns and provide peace of mind.