Understanding Low Neutrophil Levels: Implications for Blood Disorders
Low neutrophil count? Hello Doctor: I was splashed with chloramphenicol on my face on August 8, 2018. I had a blood test on August 13, 2018, and the results were as follows: WBC: 6.51*10^3/μL (reference range 3.9~10.6*10^3/μL), Seg/CBC: 40% (reference range 42~74%), Lym/CBC: 47.2...
Dr. Chen Yunfang Reply:
Hello: Based on your numbers, it does not appear to be "aplastic anemia," which is a very serious condition characterized by severe pancytopenia (which differs significantly from your report). From your report, I do not see any particular abnormalities. Thank you for yo...[Read More] Understanding Low Neutrophil Levels: Implications for Blood Disorders
Could Aplastic Anemia Progress to Myelodysplastic Syndrome?
Is it possible for aplastic anemia to transform? Hello Doctor: I was diagnosed with aplastic anemia since middle school, and it has been many years now. Although my lab results have never been very good, I have never required a blood transfusion. However, my hemoglobin has decrea...
Dr. Chen Yunfang Reply:
Hello: It's difficult to determine whether the 1% blast cells are truly malignant leukemia cells or if they are normal cells that accidentally ended up in the peripheral blood. You will need to undergo a bone marrow biopsy to get a definitive answer. It's important to p...[Read More] Could Aplastic Anemia Progress to Myelodysplastic Syndrome?
Understanding Blood Cell Abnormalities: Insights from Bone Marrow Biopsy
Abnormalities in the two blood cell lineages? Dear Doctor, The above is my blood report prior to the bone marrow aspiration and biopsy report. Since the attending physician has many patients, I am unable to ask too many questions in the clinic, so I have a few inquiries for you...
Dr. Chen Yunfang Reply:
Hello: 1. Based on the information you provided, I also agree that it is aplastic anemia. Although the definition needs to be very precise, in clinical practice, not every patient fits the standard profile, and it is impossible to completely align with what is written in textbo...[Read More] Understanding Blood Cell Abnormalities: Insights from Bone Marrow Biopsy
Understanding Mild Aplastic Anemia: Insights from Bone Marrow Biopsy Results
Mild Aplastic Anemia Hello, Doctor. This is my second time seeking your advice. Last time, you recommended that my wife undergo a bone marrow aspiration and biopsy by the attending physician. The report has come back, and the attending physician diagnosed her with mild aplastic a...
Dr. Hu Ziren Reply:
Hello, everyone: 1. Aplastic anemia is a diagnosis of exclusion (meaning it is diagnosed only after ruling out other possible causes); 2. If it is mild aplastic anemia and there are no clinical symptoms, it is recommended to simply observe. Thank you![Read More] Understanding Mild Aplastic Anemia: Insights from Bone Marrow Biopsy Results
Understanding Abnormal Blood Cell Counts: Insights into MDS and Aplastic Anemia
Abnormal blood cells Hello, doctor. My wife is 40 years old. In 2006, a blood test revealed that her white blood cell count was low at 3100, while other blood cell counts were normal. This abnormality in white blood cells persisted until 2011, with other blood cell counts remaini...
Dr. Hu Ziren Reply:
Hello, netizen: 1. While there is a temporal relationship between leukopenia and low hemoglobin levels, both should be considered together; 2. The incidence of two types of cytopenia, specifically megaloblastic anemia, is significantly higher than that of myelodysplastic syndrome...[Read More] Understanding Abnormal Blood Cell Counts: Insights into MDS and Aplastic Anemia
Understanding Aplastic Anemia: Treatment Options and Bone Marrow Transplant Challenges
Aplastic anemia Your friend's daughter has aplastic anemia and has not responded well to immunosuppressive therapy. Should treatment rely on medication or blood transfusions, or is a bone marrow transplant necessary? Her hemoglobin is 6, white blood cell count is 3000, plate...
Dr. Fan Sheng Reply:
Mier: Due to a system error, I apologize for the delayed response. The effectiveness of immunosuppressive therapy has been poor, and currently, the only option is allogeneic bone marrow transplantation. However, this carries certain risks. Sibling donors are preferred. Finding a ...[Read More] Understanding Aplastic Anemia: Treatment Options and Bone Marrow Transplant Challenges
Understanding Leukemia: Stages, Causes, and Treatment Options Explained
Leukemia Hello Doctor: My girlfriend has leukemia, and she mentioned that she has had it for many years. She told me that there are a total of four stages, and she is currently in stage three. Is this due to genetic factors, or what other reasons might contribute to it? Besides b...
Dr. Chen Sirong Reply:
1. Causes: The majority of leukemia cases have unclear origins, while a small number can be attributed to specific factors: a. Radiation exposure, such as previous radiation therapy or exposure to radiation. b. Chemical agents, including certain chemotherapy drugs and sub...[Read More] Understanding Leukemia: Stages, Causes, and Treatment Options Explained
Can Severe Aplastic Anemia Be Cured or Require Long-Term Blood Transfusions?
Severe Aplastic Anemia Hello, doctor. A few days ago, I asked you about this issue: Can severe aplastic anemia recover, or will it require long-term blood transfusions? Thank you for your response.
Dr. Fan Sheng Reply:
Connie: If aplastic anemia is caused by drug toxicity, there is a possibility that bone marrow function may recover after a period of time once the toxicity has resolved. However, we cannot expect a full recovery with certainty. Currently, red blood cell and platelet transfusions...[Read More] Can Severe Aplastic Anemia Be Cured or Require Long-Term Blood Transfusions?
Understanding Poor Hematopoietic Function: A Case Study in Elderly Patients
Poor hematopoietic function? Hello, my grandfather is 85 years old. Two weeks ago, he visited a clinic for a headache and received a flu vaccine. A few days later, he experienced dizziness, and that same evening after dinner, he vomited. He was then taken to the emergency departm...
Dr. Fan Sheng Reply:
Connie: This should be classified as severe aplastic anemia, which is characterized by the cessation of hematopoiesis in the bone marrow. The causes of this condition include drug toxicity and autoimmune factors, among others. However, the majority of cases remain idiopathic. Lit...[Read More] Understanding Poor Hematopoietic Function: A Case Study in Elderly Patients
Understanding Aplastic Anemia: Treatment Options and Travel Considerations
Questions Hi! About 2 weeks ago, I wrote an email to see if you could refer me to any hospital for leukemia. Thanks for your attention. My friend finally got the English name for her sister’s disease—“Aplastic Anemia.” She is actually in Thailand and is Thai. For this kind of dis...
Dr. Fan Sheng Reply:
Dear Vivien, Aplastic anemia is referred to as "再生不良性貧血" in Mandarin. It is not a malignant disease, but severe forms of aplastic anemia can be life-threatening. The best treatment is hematopoietic stem cell transplantation, using either bone marrow or peripheral blood...[Read More] Understanding Aplastic Anemia: Treatment Options and Travel Considerations