Osteogenesis imperfecta, Orthopedics FAQ

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Understanding Tibial Fractures and Osteogenesis Imperfecta in Children

Tibial fracture/Osteogenesis imperfecta (OI) Hello, Doctor: My child, who is 8 years old, suffered an injury in a car accident resulting in a spiral fracture of the left tibial shaft. The doctor used a telescopic intramedullary nail with two fixation screws. I would like to ask t...


Dr. Li Wenhong Reply:
Hello: 1. The effectiveness of rehabilitation therapy varies from person to person, especially in children where the differences can be significant. Please be patient and cooperate with the rehabilitation therapy for six months. 2. Normal removal of internal fixation devices requ...

[Read More] Understanding Tibial Fractures and Osteogenesis Imperfecta in Children


Understanding Femoral Deformity: Measurement Techniques and Insights

Deformity of the femur in the lower extremity? Hello, I would like to ask if the curvature of the tibia (as seen on an X-ray) indicates femoral deformity? What is the correct method to measure the degree of femoral deformity? Thank you.


Dr. Li Wenhong Reply:
The bones of the lower leg are the tibia and fibula (not the femur). If we are referring to the diaphysis (midsection), it should be straight. If the X-ray shows curvature or deformity, there could be many reasons, such as improper healing of a fracture, congenital pseudarthrosis...

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Understanding Fractures in Newborns: Recovery and Risks After Delivery

Fractures due to childbirth? Hello Dr. Lee! During a cesarean section, my family member's baby suffered a complete fracture of the left thigh. I have the following questions: 1. What is the likelihood of recovery? 2. Is the incidence of such birth injuries high? Since this h...


Dr. Li Wenlin Reply:
Hello: In response to your question, first of all, congratulations on the arrival of your baby. The likelihood of a femoral fracture during delivery is quite low, but it may require further investigation. There is a condition known as osteogenesis imperfecta, commonly referred to...

[Read More] Understanding Fractures in Newborns: Recovery and Risks After Delivery


Understanding Type I Collagen and Its Role in Osteogenesis Imperfecta (OI)

Regarding OI (Osteogenesis Imperfecta)? Hello, doctor! The cause of Osteogenesis Imperfecta (OI) is related to the deficiency of type I collagen. I would like to ask you, what is type I collagen? Thank you!


Dr. Li Wenlin Reply:
Hello: In response to your question, collagen fibers are the main component of all connective tissues. Currently, it is known that 20 genes influence the production of collagen fibers, and there are thirteen different types of collagen identified so far. These can be categorized ...

[Read More] Understanding Type I Collagen and Its Role in Osteogenesis Imperfecta (OI)


Understanding and Treating Osteogenesis Imperfecta: A Guide

Glass-like fracture The rehabilitation doctor suspects that my symptoms are indicative of a glassy fracture. How should a glassy fracture be treated?


Dr. Shi Qiming Reply:
Dear Mr. Dong, Due to the absence of a specific medical term for "glass fracture," I am unable to answer your question. Could you please provide the English medical term for "glass fracture" in your next correspondence? I will then be able to address your inq...

[Read More] Understanding and Treating Osteogenesis Imperfecta: A Guide


Understanding Osteogenesis Imperfecta: Causes, Symptoms, and Treatment

What is osteogenesis imperfecta? Hello Dr. Lee: Could you please explain what osteogenesis imperfecta is? I have not found much information, so I would appreciate your introduction. Thank you!


Dr. Li Wenlin Reply:
Hello, in response to your inquiry: Osteogenesis Imperfecta, commonly known as "brittle bone disease," is a condition caused by mutations in type I collagen. Approximately 1 in 20,000 newborns is affected by this disorder. The clinical manifestations vary significantly ...

[Read More] Understanding Osteogenesis Imperfecta: Causes, Symptoms, and Treatment


What is Bone Cement? Composition, Effectiveness, and Use in Osteogenesis Imperfecta

What is bone cement? What are the components of so-called bone cement? How effective is it? Is it suitable for patients with osteogenesis imperfecta?


Dr. Lin Junliang Reply:
Bone cement is a chemically synthesized filler that is non-adhesive and does not promote bone growth. Currently, it is more commonly used in orthopedic applications related to artificial joints. Patients with osteogenesis imperfecta rarely receive treatment with bone cement. It m...

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Understanding Osteogenesis Imperfecta: Symptoms, Causes, and Treatments

Osteopetrosis What is osteogenesis imperfecta, why does it occur, what goes wrong in the body, what are the symptoms, how is it treated, and how does it differ from brittle bone disease?


Dr. Shi Guozheng Reply:
I am not sure if you are referring to osteopetrosis, also known as marble bone disease. In this condition, the bones appear very white on X-rays due to poor remodeling, leading to excessive calcification without resorption. These bones are more brittle and prone to fractures, and...

[Read More] Understanding Osteogenesis Imperfecta: Symptoms, Causes, and Treatments