Menstrual Irregularities After Using Ru486: Causes and Concerns - Obstetrics and Gynecology

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Menstrual-related issues


I apologize for the inconvenience, but I would like to ask about my menstrual cycle.
I took Ru486 on December 9, 2015, and my bleeding period ended in January.
I can't recall the details of my first menstrual cycle in January, but in early February, I experienced a heavier flow lasting about 7 days.
In early March, the flow was very light (using a regular tampon, it was not saturated after 8 hours), but the duration was normal.
My cycle length is 25 days.
Now, at the end of March, I have started my period again with a heavy flow (using a night pad, it overflowed after about 7 hours) and there are many small blood clots.
A week before this period, I experienced some dull pain, and the cycle length was only 23 days.
Could you please explain the possible reasons for this?
*The above-mentioned situations are compared to before the abortion: duration was 5-6 days, cycle length was about 30 days, and the heaviest flow was similar to using a night pad for about 8 hours.*

Yuki, 20~29 year old female. Ask Date: 2016/03/27

Dr. Zhang Kunmin reply Obstetrics and Gynecology


Hello, the factors that can affect the menstrual cycle or cause bleeding outside of menstruation are numerous, including environmental factors, lifestyle, stress, emotional instability, diet, age, and lesions in the uterus or cervix, among others.
It is advisable to consult a gynecologist to determine whether it is due to hormonal imbalance or other reasons.
Thank you! Wishing you peace and health.
Dr.
Zhang

Reply Date: 2016/03/27

More Info


Menstrual irregularities can be a common concern for individuals who have used medications like RU486 (mifepristone), which is primarily used for medical abortion. The changes in your menstrual cycle following the use of RU486 can be attributed to several factors, including hormonal fluctuations, the body's adjustment post-abortion, and potential underlying conditions.


Understanding the Changes
1. Hormonal Fluctuations: RU486 works by blocking the hormone progesterone, which is essential for maintaining pregnancy. After its use, the body undergoes significant hormonal changes as it transitions back to a non-pregnant state. This can lead to irregularities in the menstrual cycle, including variations in flow, duration, and cycle length.

2. Post-Abortion Recovery: After an abortion, it is normal for the menstrual cycle to take some time to regulate. The first few cycles may be unpredictable, with variations in flow and duration. Your experience of having a heavier flow in February followed by a lighter flow in March is not uncommon. The body may still be adjusting to the hormonal changes, which can manifest as fluctuations in menstrual characteristics.

3. Cycle Length Variations: The changes in cycle length you’ve described—from 25 days to 23 days—can also be attributed to the body’s adjustment post-RU486. It is not unusual for cycles to vary in length during this period. However, if the cycles continue to shorten or if you experience significant discomfort, it may warrant further investigation.

4. Presence of Blood Clots: The presence of small blood clots during menstruation can occur, especially if the flow is heavier than usual. Blood clots can form when the body sheds the uterine lining more rapidly. While this can be normal, if you notice an increase in the size or frequency of clots, or if they are accompanied by severe pain, it is advisable to consult a healthcare provider.

5. Pain and Discomfort: The "dull pain" you experienced a week before your recent period could be related to ovulation or the onset of menstruation. However, if the pain is severe or persistent, it could indicate other issues, such as endometriosis or fibroids, which may require further evaluation.


When to Seek Medical Attention
While some irregularities can be expected after using RU486, there are certain signs that should prompt you to seek medical advice:
- Severe Pain: If you experience significant pain that interferes with daily activities, it is important to consult a healthcare provider.

- Heavy Bleeding: If you soak through a pad or tampon every hour for several hours, or if you pass large clots consistently, you should seek medical attention.

- Cycle Consistency: If your cycles do not stabilize after a few months or if they continue to be irregular, it may be beneficial to discuss this with a healthcare professional.

- Other Symptoms: If you experience symptoms such as fever, chills, or unusual discharge, these could indicate an infection or other complications.


Conclusion
In summary, the menstrual irregularities you are experiencing after using RU486 can be attributed to hormonal changes and the body’s adjustment post-abortion. While some variations are normal, it is essential to monitor your symptoms and seek medical advice if you notice concerning changes. Regular follow-ups with a healthcare provider can help ensure that any underlying issues are addressed and that your reproductive health is managed appropriately.

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