Impact of Hair Growth Products on Sperm Health: What to Know Before Conceiving

I would like to inquire about the effects of hair growth solutions on sperm?

Hello Dr.
Zhang, I am planning to conceive in six months.
Currently, I am using a hair growth solution, Dualgen 15, which contains the following ingredients: Minoxidil 15%, Azelaic acid 5%, Retinol 0.025%, Caffeine 0.001%, Ethanol, Glycerin, and Water.
I would like to inquire whether Minoxidil, Azelaic acid, and Retinol can remain in semen.
I am concerned about potential growth issues for the child, so I would like to know if I should continue using it or pause its use.
Thank you.

Ting, 30~39 year old female. Ask Date: 2016/03/29

Dr. Zhang Kunmin reply Obstetrics and Gynecology

Hello, the use of ROGAINE 5% Minoxidil does not affect male reproductive and sexual function.
However, Azelaic acid and Retinol are not recommended for use in pregnant women, and there are no reports of effects on male sperm.
Thank you! Wishing you peace and health, Dr.
Chang.

Reply Date: 2016/03/29

More Info

When considering the impact of hair growth products on sperm health and potential effects on conception, it's essential to understand the ingredients in these products and their pharmacokinetics. In your case, you are using Dualgen 15, which contains Minoxidil, Azelaic Acid, and Retinol, among other components.

Minoxidil
Minoxidil is a topical vasodilator primarily used to treat hair loss. It works by increasing blood flow to hair follicles, thereby promoting hair growth. Research indicates that Minoxidil is minimally absorbed into the bloodstream when applied topically, with systemic absorption being quite low. Consequently, the likelihood of Minoxidil affecting sperm quality or being present in significant amounts in semen is very low. Studies have not shown any adverse effects on fertility or fetal development associated with Minoxidil use in men.

Azelaic Acid
Azelaic Acid is another topical agent known for its anti-inflammatory and antibacterial properties, often used in treating acne and rosacea. Similar to Minoxidil, Azelaic Acid is poorly absorbed through the skin, which means that it is unlikely to have any significant systemic effects, including on sperm health. There is no substantial evidence linking Azelaic Acid to fertility issues or developmental problems in offspring.

Retinol
Retinol, a form of Vitamin A, is commonly used in skincare for its anti-aging properties. While high doses of Vitamin A can be teratogenic (capable of causing developmental malformations), the amount absorbed through topical application is generally considered safe. The risk of significant systemic absorption leading to adverse effects on sperm quality or fetal development is minimal when used in typical cosmetic concentrations.

Conclusion and Recommendations
Given the low systemic absorption of these ingredients, it is unlikely that they would significantly impact sperm health or be present in your semen in amounts that could affect fetal development. However, if you have concerns about any potential effects, it may be prudent to pause the use of these products as you prepare for conception.
Additionally, it's always a good idea to consult with a healthcare provider or a fertility specialist regarding your specific situation. They can provide personalized advice based on your health history and any other medications or supplements you may be taking.
In summary, while the ingredients in Dualgen 15 are not associated with significant risks to sperm health or fetal development, if you feel more comfortable discontinuing their use while trying to conceive, that is a valid choice. Prioritizing your peace of mind and ensuring a healthy conception process is essential.

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