Can Chronic Pharyngitis Lead to Lymphoma? the Risks - Otolaryngology

Share to:

Chronic pharyngitis does not directly cause lymphoma. However, chronic inflammation in the body can be associated with an increased risk of certain types of cancer, including lymphomas. It is important to consult a healthcare professional for a comprehensive evaluation and understanding of individual risk factors?


Hello doctor, since last month I have been experiencing a sensation of pressure in my throat and a feeling of fullness in my ears.
I went to the hospital and underwent a laryngoscopy, which revealed chronic pharyngitis.
I have been taking medication but have not seen any improvement.
Additionally, I noticed that the side of my jaw feels slightly swollen compared to the right side, but it is not painful when pressed.
Can chronic pharyngitis lead to lymphadenopathy? Do I need to undergo any imaging studies? Thank you.

Wang Yizhen, 20~29 year old female. Ask Date: 2016/03/30

Dr. Zheng Jueyi reply Otolaryngology


Hello, chronic pharyngitis generally does not cause lymphadenopathy.
The swelling in that area could possibly be related to the submandibular gland or lymph nodes.
If it continues to enlarge, it is advisable to return for follow-up.
Wishing you peace and good health.
Sincerely, Dr.
Cheng Jue-Yi, Director of the Department of Otolaryngology, Taoyuan Hospital, Ministry of Health and Welfare.

Reply Date: 2016/03/30

More Info


Chronic pharyngitis is a condition characterized by persistent inflammation of the pharynx, which can lead to various symptoms, including a sensation of pressure in the throat, ear fullness, and discomfort. While chronic pharyngitis itself is not directly linked to lymphoma, it is essential to understand the broader context of chronic inflammation and its potential implications for health.

Chronic inflammation, in general, has been associated with an increased risk of certain types of cancer, including lymphomas. This association is primarily due to the fact that chronic inflammation can lead to changes in the cellular environment, promoting conditions that may facilitate malignant transformations. However, it is crucial to note that the risk of developing lymphoma from chronic pharyngitis specifically is not well-established in medical literature. The inflammation in chronic pharyngitis is usually due to factors such as allergies, irritants (like smoke or pollution), or infections, rather than a direct precursor to malignancy.

Regarding your symptoms, the sensation of pressure in your throat and the fullness in your ears can indeed be related to chronic pharyngitis. The swelling you feel on the side of your jaw could be due to lymphadenopathy, which is the enlargement of lymph nodes. This can occur in response to infections or inflammation in the area, including chronic pharyngitis. Lymph nodes can swell as they react to various stimuli, including infections, and this does not necessarily indicate the presence of lymphoma.

Given your symptoms and the lack of improvement with medication, it would be prudent to follow up with your healthcare provider. They may recommend imaging studies, such as an ultrasound or CT scan, to evaluate the swollen area and assess the lymph nodes further. This can help rule out any serious conditions, including lymphoma, especially if there are concerning features such as persistent swelling, changes in size, or other systemic symptoms like weight loss or night sweats.

In summary, while chronic pharyngitis can lead to lymph node enlargement due to inflammation, it is not a direct cause of lymphoma. However, persistent symptoms warrant further investigation to ensure that any underlying issues are addressed. It is always better to err on the side of caution and seek further evaluation if you have concerns about your health. Regular follow-ups with your healthcare provider are essential to monitor your condition and adjust treatment as necessary.

Similar Q&A

Chronic Throat Inflammation: When Does It Lead to Throat Cancer?

Hello Doctor: This is my second inquiry. I would like to know under what circumstances chronic pharyngitis can progress to pharyngeal cancer. Currently, I have recurrent throat inflammation that fluctuates, accompanied by chills and fever, headaches, dizziness, yellow and white s...


Dr. Zheng Jueyi reply Otolaryngology
Hello: Throat cancer is often related to long-term chronic irritation, with chronic pharyngitis being one of the factors. Smoking, air pollution, and other related issues can contribute as well. If gastroesophageal reflux persists without improvement, it is recommended to continu...

[Read More] Chronic Throat Inflammation: When Does It Lead to Throat Cancer?


Understanding Lymphadenopathy: Causes, Concerns, and Cancer Risks

I recently noticed a round swelling about 1 centimeter in size on the right side of my neck that feels a bit painful. I saw a doctor who said it is lymphadenopathy and advised me to get blood tests for the Epstein-Barr virus (EBV). This makes me a bit worried. Can you explain how...


Dr. Xu Jiazhen reply Otolaryngology
Hello: In response to your question, there are approximately 100-300 lymph nodes in the neck. The causes of lymphadenopathy can be categorized into five main types: (1) immune responses, such as tonsillitis or pharyngitis; (2) direct infection of the lymph nodes; (3) metastasis o...

[Read More] Understanding Lymphadenopathy: Causes, Concerns, and Cancer Risks


Understanding Chronic Pharyngitis and Follicular Changes in the Throat

Hello, Doctor! I am currently a senior in high school. About a year and a half ago, I started experiencing discomfort in my throat, pain, and excessive phlegm. I have visited several doctors, and a few of them diagnosed me with chronic pharyngitis. According to them, it may be ca...


Dr. Zheng Jueyi reply Otolaryngology
Hello, the follicular tissue in the pharynx is lymphoid tissue of the larynx. If there are no significant abnormalities upon examination, it is mostly related to chronic inflammation. It is recommended to maintain good lifestyle habits, such as drinking plenty of water, reducing ...

[Read More] Understanding Chronic Pharyngitis and Follicular Changes in the Throat


Understanding Lymphoid Hyperplasia in the Throat: Causes and Treatment

Hello, Doctor: I opened my mouth to examine my throat and found that the lymphoid follicles in the pharyngeal wall are hyperplastic. One of the follicles appears yellowish-white, while the others are red. I would like to know what this means and whether treatment is necessary. I ...


Dr. Zheng Jueyi reply Otolaryngology
Hello, that should be the lymphoid tissue of the posterior pharyngeal wall. The redness is normal, while the yellowish-white color may sometimes just be secretions that are trapped. If there is no sore throat, it may just be mild inflammation. It is advisable to drink plenty of w...

[Read More] Understanding Lymphoid Hyperplasia in the Throat: Causes and Treatment


Related FAQ

Chronic Pharyngitis

(Otolaryngology)

Lymphadenitis

(Otolaryngology)

Lymphadenopathy

(Otolaryngology)

Tonsillitis

(Otolaryngology)

Throat Disease

(Otolaryngology)

Cervical Lymph Nodes

(Otolaryngology)

Mumps

(Otolaryngology)

Nasopharyngeal Carcinoma

(Otolaryngology)

Lymphadenitis

(Family Medicine)

Neck Mass

(Otolaryngology)