Lymphoid Hyperplasia in the Throat: Causes and Treatment - Otolaryngology

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Throat wall issues?


Hello, Doctor: I opened my mouth to examine my throat and found that the lymphoid follicles in the pharyngeal wall are hyperplastic.
One of the follicles appears yellowish-white, while the others are red.
I would like to know what this means and whether treatment is necessary.
I do not have any other significant throat symptoms, but I sometimes wake up with a dry throat.
I have seen my family doctor, who mentioned that I have mild nasal allergies and that sleeping in an air-conditioned room makes me breathe through my mouth, which can lead to a drier throat.
He said it's not a concern and that it might just be due to mucus obstruction.

Zhe, 30~39 year old female. Ask Date: 2014/08/11

Dr. Zheng Jueyi reply Otolaryngology


Hello, that should be the lymphoid tissue of the posterior pharyngeal wall.
The redness is normal, while the yellowish-white color may sometimes just be secretions that are trapped.
If there is no sore throat, it may just be mild inflammation.
It is advisable to drink plenty of water and avoid irritating foods, as it generally improves on its own.
However, if there is persistent pain or fever, it would be necessary to consider medication treatment.
Wishing you safety and health.
Sincerely, Dr.
Cheng Jue-Yi, Director of the Department of Otolaryngology, Taoyuan Hospital, Ministry of Health and Welfare.

Reply Date: 2014/08/11

More Info


Lymphoid hyperplasia in the throat, particularly in the context of the tonsils and pharyngeal tissue, is a common condition that can arise due to various factors, including infections, allergies, and environmental irritants. The presence of lymphoid follicles, particularly those that appear yellowish-white, may indicate a localized immune response. This response is often a reaction to pathogens or irritants, leading to an increase in lymphoid tissue as the body attempts to fight off an infection or inflammation.

In your case, the observation of lymphoid follicles in the throat wall, especially with one follicle showing a yellowish-white color, suggests that there may be some form of localized inflammation or infection. The yellowish-white color could be due to the accumulation of pus or necrotic tissue, which is common in cases of acute infections, such as viral or bacterial pharyngitis. However, it is also possible that this is simply a result of mucus accumulation, especially if you have been experiencing dryness in your throat due to mouth breathing, which can occur in individuals with nasal allergies.

The fact that you do not have significant throat symptoms, aside from occasional dryness, is a positive sign. It suggests that while there may be some degree of inflammation or hyperplasia, it is not currently causing major issues. Your physician's assessment of mild nasal allergies aligns with this, as allergic reactions can lead to post-nasal drip, which may irritate the throat and contribute to the appearance of lymphoid hyperplasia.

As for treatment, it largely depends on the underlying cause of the lymphoid hyperplasia. If it is related to allergies, managing your allergic symptoms through antihistamines or avoiding known allergens may help reduce the inflammation. Staying hydrated and using a humidifier in your living space can also alleviate throat dryness. If the condition is due to an infection, supportive care such as rest, hydration, and possibly the use of over-the-counter pain relievers or throat lozenges may be recommended.
In cases where lymphoid hyperplasia is persistent or accompanied by more severe symptoms, further investigation may be warranted. This could include imaging studies or a referral to an ENT specialist for a more detailed examination. However, based on your description and the assessment by your family physician, it seems that close monitoring may be sufficient at this time.

In summary, lymphoid hyperplasia in the throat is often a benign condition that reflects the immune system's response to various stimuli. While it can be associated with infections or allergies, the absence of significant symptoms is reassuring. Treatment should focus on addressing any underlying causes, such as allergies or infections, and maintaining throat comfort. If symptoms worsen or new symptoms develop, further evaluation would be advisable.

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